scholarly journals HPLC-ESI-QTOF-MS as a Powerful Analytical Tool for Characterising Phenolic Compounds in Olive-leaf Extracts

2012 ◽  
Vol 24 (3) ◽  
pp. 213-223 ◽  
Author(s):  
Rosa Quirantes-Piné ◽  
Jesús Lozano-Sánchez ◽  
Miguel Herrero ◽  
Elena Ibáñez ◽  
Antonio Segura-Carretero ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Analytical Tool ◽  
Olive Leaf ◽  
Leaf Extracts ◽  
Powerful Analytical Tool

Phenolic compounds and antioxidant activity of olive leaf extracts

2011 ◽  
Vol 26 (2) ◽  
pp. 186-189 ◽  
Author(s):  
Vassiliki G. Kontogianni ◽  
Ioannis P. Gerothanassis
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Olive Leaf ◽  
Leaf Extracts

Phenolic compounds and in vitro immunomodulatory properties of three Andalusian olive leaf extracts

2016 ◽  
Vol 22 ◽  
pp. 270-277 ◽  
Author(s):  
Nassima Talhaoui ◽  
Teresa Vezza ◽  
Ana María Gómez-Caravaca ◽  
Alberto Fernández-Gutiérrez ◽  
Julio Gálvez ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Olive Leaf ◽  
Leaf Extracts ◽  
Immunomodulatory Properties

scholarly journals Addition of Olive Leaf Extract to a Mixture of Algae and Extra Virgin Olive Oils Decreases Fatty Acid Oxidation and Synergically Attenuates Age-Induced Hypertension, Sarcopenia and Insulin Resistance in Rats

Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1066
Author(s):  
Daniel González-Hedström ◽  
María de la Fuente-Fernández ◽  
Teresa Priego ◽  
Ana Isabel Martín ◽  
Sara Amor ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Vascular Function ◽  
Virgin Olive Oil ◽  
Serum Levels ◽  
Acid Oxidation ◽  
Antioxidant Compounds ◽  
Mrna Levels ◽  
Omega 3 ◽  
Olive Leaf ◽  
Leaf Extracts

Olive-derived products, such as virgin olive oil (EVOO) and/or olive leaf extracts (OLE), exert anti-inflammatory, insulin-sensitizing and antihypertensive properties and may be useful for stabilizing omega 3 fatty acids (n-3 PUFA) due to their high content in antioxidant compounds. In this study, the addition of OLE 4:0.15 (w/w) to a mixture of algae oil (AO) rich in n-3 PUFA and EVOO (25:75, w/w) prevents peroxides formation after 12 months of storage at 30 °C. Furthermore, the treatment with the oil mixture (2.5 mL/Kg) and OLE (100 mg/Kg) for 24 month old Wistar rats in 21 days improved the lipid profile, increased the HOMA-IR and decreased the serum levels of miRNAs 21 and 146a. Treatment with this new nutraceutical also prevented age-induced insulin resistance in the liver, gastrocnemius and visceral adipose tissue by decreasing the mRNA levels of inflammatory and oxidative stress markers. Oil mixture + OLE also attenuated the age-induced alterations in vascular function and prevented muscle loss by decreasing the expression of sarcopenia-related markers. In conclusion, treatment with a new nutraceutical based on a mixture of EVOO, AO and OLE is a useful strategy for improving the stability of n-3 PUFA in the final product and to attenuate the cardiometabolic and muscular disorders associated with aging.

Antioxidant enriched olive leaf extracts show antiproliferative activity in cellular models of breast cancer

2017 ◽  
Vol 108 ◽  
pp. S92
Author(s):  
María Losada-Echeberría ◽  
Amani Taamalli ◽  
Vicente Micol ◽  
María Herranz-López ◽  
David Arráez-Román ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Antiproliferative Activity ◽  
Olive Leaf ◽  
Leaf Extracts ◽  
Cellular Models

scholarly journals Evaluation of Antioxidant Activity, Total Flavonoids, Tannins and Phenolic Compounds in Psychotria Leaf Extracts

Antioxidants ◽  
2014 ◽  
Vol 3 (4) ◽  
pp. 745-757 ◽  
Author(s):  
Anelise Formagio ◽  
Carla Volobuff ◽  
Matheus Santiago ◽  
Claudia Cardoso ◽  
Maria Vieira ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Total Flavonoids ◽  
Leaf Extracts

scholarly journals Coelenterazine-Dependent Luciferases as a Powerful Analytical Tool for Research and Biomedical Applications

2020 ◽  
Vol 21 (20) ◽  
pp. 7465 ◽  
Author(s):  
Vasilisa V. Krasitskaya ◽  
Eugenia E. Bashmakova ◽  
Ludmila A. Frank
Keyword(s):  
Analytical Methods ◽  
Analytical Tool ◽  
Biological Research ◽  
Research Areas ◽  
Enzyme Substrate ◽  
Highly Sensitive ◽  
Powerful Analytical Tool ◽  
Fundamental Research ◽  
Common Group ◽  
First Time

The functioning of bioluminescent systems in most of the known marine organisms is based on the oxidation reaction of the same substrate—coelenterazine (CTZ), catalyzed by luciferase. Despite the diversity in structures and the functioning mechanisms, these enzymes can be united into a common group called CTZ-dependent luciferases. Among these, there are two sharply different types of the system organization—Ca2+-regulated photoproteins and luciferases themselves that function in accordance with the classical enzyme–substrate kinetics. Along with deep and comprehensive fundamental research on these systems, approaches and methods of their practical use as highly sensitive reporters in analytics have been developed. The research aiming at the creation of artificial luciferases and synthetic CTZ analogues with new unique properties has led to the development of new experimental analytical methods based on them. The commercial availability of many ready-to-use assay systems based on CTZ-dependent luciferases is also important when choosing them by first-time-users. The development of analytical methods based on these bioluminescent systems is currently booming. The bioluminescent systems under consideration were successfully applied in various biological research areas, which confirms them to be a powerful analytical tool. In this review, we consider the main directions, results, and achievements in research involving these luciferases.

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