The optimum property concept?part II the relative order in failure property maxima with increasing filler levels

1984 ◽  
Vol 5 (4) ◽  
pp. 339-346 ◽  
Author(s):  
F. K. Lautenschlaeger
1998 ◽  
Vol 88 (3) ◽  
pp. 744-750 ◽  
Author(s):  
Vivian Y. Hou ◽  
Carol A. Hirshman ◽  
Charles W. Emala

Background Neuromuscular relaxants such as pancuronium bind to M2 and M3 muscarinic receptors as antagonists. Blockade of muscarinic receptors in atria of the M2 subtype mediates tachycardia. In the lung, blockade of M2 receptors on parasympathetic nerves potentiates vagally induced bronchospasm, whereas blockade of M3 receptors on bronchial smooth muscle inhibits bronchospasm. The current study was designed to quantify the affinity of a series of neuromuscular relaxants for the M2 and M3 muscarinic receptors, which were individually stably transfected in Chinese hamster ovary cell lines. Methods Competitive radioligand binding assays determined the relative binding affinities of the neuromuscular relaxants pancuronium, succinylcholine, mivacurium, doxacurium, atracurium, rocuronium, gallamine, and pipecuronium for the muscarinic receptor in the presence of a muscarinic receptor antagonist (3H-QNB) in membranes prepared from cells individually expressing either the M2 or M3 muscarinic receptor. Results All muscle relaxants evaluated displaced 3H-QNB from muscarinic receptors. The relative order of potency for the M2 muscarinic receptor (highest to lowest) was pancuronium, gallamine, rocuronium, atracurium, pipecuronium, doxacurium, mivacurium, and succinylcholine. The relative order of potency for the M3 muscarinic receptor (highest to lowest) was pancuronium, atracurium, pipecuronium, rocuronium, mivacurium, gallamine, succinylcholine, and doxacurium. Conclusions All neuromuscular relaxants studied had affinities for the M2 and M3 muscarinic receptor, but only pancuronium and gallamine had affinities within the range of concentrations achieved with clinical use. The high affinities of gallamine and pancuronium for the M2 muscarinic receptor are consistent with a mechanism of M2 receptor blockade in relaxant-induced tachycardia.


2013 ◽  
Vol 36 (2) ◽  
pp. 201-228 ◽  
Author(s):  
Piet Mertens

This study explores formal criteria for the classification of adverbs in French. Distributional analysis tests whether adverbs appear in particular morpho-syntactic contexts, including syntactic constructions. It analyses combinations of adverbs, and their relative order in particular syntactic contexts. Finally it tests whether using adverbs in these positions imposes prosodic restrictions. These criteria result in a classification which is compatible with those found in major studies on this topic.


1968 ◽  
Vol 46 (6) ◽  
pp. 987-993 ◽  
Author(s):  
J. P. Guertin ◽  
M. Onyszchuk

Tensimetric titrations at −78° of silicon tetrafluoride with ethylene oxide, trimethylene oxide, tetrahydrofuran, tetrahydropyran, and dimethyl ether prove the formation of only 1:2 complexes, SiF4•2-(ether). All are unstable at 25° and either dissociate completely, as do SiF4•2(CH2)4O, SiF4•2(CH2)5O, and SiF4•2(CH3)2O, or decompose into SiF4 and a polymethylene oxide polymer, as do SiF4•2(CH2)2O and SiF4•2(CH2)3O. Silicon tetrafluoride does not coordinate with 1,4-dioxane in the range −94 to 25° and less than 1 atm pressure. Condensed phase heats of dissociation of SiF4•2(ether) complexes follow the order (CH2)3O > (CH2)4O > (CH2)5O ≥ (CH2)2O > (CH3)2O, which suggests that this is the relative order of basicities towards SiF4.


2021 ◽  
Author(s):  
Shichao Kan ◽  
Yigang Cen ◽  
Yang Li ◽  
Vladimir Mladenovic ◽  
Zhihai He

2018 ◽  
Vol 31 (8) ◽  
pp. 969-976 ◽  
Author(s):  
Wang Chunbo ◽  
Jiang Haifu ◽  
Tian Dongbo ◽  
Qin Wei ◽  
Chen Chunhai ◽  
...  

The differences among polymers containing silicon or phosphorus, 20% polyhedral oligomeric silsesquioxane polyimide (20%-POSS-PI), 30% polysiloxane- block-polyimides (30%-PSX-PI), poly(siloxane imide) homopolymer (PSX-PI), and arylene ether phosphine oxide homopolymer (P-PPO), on mass loss, erosion yield, and surface morphology were elucidated. The tolerance against atomic oxygen (AO) was improved versus Kapton®H after introducing silicon or phosphorus to the polymers. The relative order of the mass loss was PSX-PI < P-PPO < 20%-POSS-PI < 30%-PSX-PI. In contrast, the erosion yields of 30%-PSX-PI, 20%-POSS-PI, and P-PPO decreased by orders of magnitude (PSX-PI declined by about two orders). The surface of Kapton®H was seriously eroded by AO exhibiting a “carpet-like” shape, and the roughness of the surface of Kapton®H became remarkable as the AO fluence increased. PSX-PI, P-PPO, 20%-POSS-PI, and 30%-PSX-PI at an AO fluence of 5.2 × 1020 atoms/cm2 had different surface morphologies, and the relative order of the surface roughness was PSX-PI < 30%-PSX-PI < 20%-POSS-PI < P-PPO. The 30%-PSX-PI and PSX-PI had minor mass losses and a smooth surface. This kind of material might replace inorganic coatings for applications in low earth orbit.


1974 ◽  
Vol 23 (3) ◽  
pp. 335-359 ◽  
Author(s):  
Joan L. Betz ◽  
Jane E. Brown ◽  
Patricia H. Clarke ◽  
Martin Day

SUMMARYMutants ofPseudomonas aeruginosa, which differed in amide growth phenotype from the wild-type strain, were subjected to genetic analysis using the generalized transducing phage F116. The map order of some mutational sites was determined by 3-factor crosses in which a mutation in the linked regulator geneamiRwas used as the outside marker to determine the relative order of mutations in the amidase structural geneamiE. Acetamide-positive transductants were recovered in crosses between amidase-negative strains and strains PhB3(PAC377), V2(PAC353) and V5(PAC356) producing mutant amidases which hydrolyse phenylacetamide and valeramide but not acetamide. Some recombinants carried the mutationamiE16 determining the properties of the mutant B amidase produced by strain B6(PAC351) from which both PhB and V class mutants were derived, while other recombinants produced A amidase determined by the wild-typeamiEgene.


2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Luis Manuel Sánchez Ruiz ◽  
Sanjib Kumar Datta ◽  
Tanmay Biswas ◽  
Golok Kumar Mondal

The relative order of growth gives a quantitative assessment of how different functions scale each other and to what extent they are self-similar in growth. In this paper for any two positive integerspandq, we wish to introduce an alternative definition of relative(p,q)th order which improves the earlier definition of relative(p,q)th order as introduced by Lahiri and Banerjee (2005). Also in this paper we discuss some growth rates of entire functions on the basis of the improved definition of relative(p,q)th order with respect to another entire function and extend some earlier concepts as given by Lahiri and Banerjee (2005), providing some examples of entire functions whose growth rate can accordingly be studied.


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