Risk of subsequent colorectal cancers after a solid tumor in childhood: Effects of radiation therapy and chemotherapy

2018 ◽  
Vol 66 (2) ◽  
pp. e27495 ◽  
Author(s):  
Rodrigue S. Allodji ◽  
Nadia Haddy ◽  
Giao Vu-Bezin ◽  
Agnès Dumas ◽  
Brice Fresneau ◽  
...  
Author(s):  
Rodrigue S. Allodji ◽  
Boris Schwartz ◽  
Cristina Veres ◽  
Nadia Haddy ◽  
Carole Rubino ◽  
...  

1976 ◽  
Vol 127 (6) ◽  
pp. 935-939 ◽  
Author(s):  
AA De Smet ◽  
LR Kuhns ◽  
JV Fayos ◽  
JF Holt

2005 ◽  
Vol 1 (1) ◽  
pp. 187
Author(s):  
R.M. Valeri ◽  
K. Vahtsevanos ◽  
E. Aslanidou ◽  
A. Ntomouchtsis ◽  
Z. Teieioudis ◽  
...  

2019 ◽  
Vol 39 (12) ◽  
Author(s):  
Yonghu Xu ◽  
Zihan Zhang ◽  
Guofeng Xu

Abstract Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. Outcome for children with high-risk NB remains unsatisfactory. Accumulating evidence suggests that tripartite motif (TRIM) family proteins express diversely in various human cancers and act as regulators of oncoproteins or tumor suppressor proteins. This review summarizes the TRIM proteins involving in NB and the underlying molecular mechanisms. We expect these new insights will provide important implications for the treatment of NB by targeting TRIM proteins.


Author(s):  
O. Sukhina ◽  
◽  
K. Nemaltsova ◽  
O. Panov ◽  
◽  
...  

Radiation therapy for malignant tumors of the female genital area, even with the use of modern radiotherapy equipment and dosimetric planning, causes the development of local radiation changes. An approach involving methods of general and local exposure is used in their treatment. One of the most promising directions is the creation of optimal combinations of medicines (in the form of ointments, gels, aerosols, suppositories, etc.), which have a therapeutic effect on the inflammatory process. The article reflects the clinical course and stage of occurrence of late radiation reactions of the skin, vaginal/cervix mucosa, bladder, and intestines, as well as the features of their treatment. Literary data and own practical experience in the treatment of radiation complications are presented. When reviewing the topic under study, it could be concluded that the leading cause of the development of local radiation damage is the errors in the planning and implementation of radiation therapy, when high absorbed doses that exceed the tolerance of healthy tissues are used. Another reason for this is the poor accounting for dose distribution of ionizing radiation in tissues, the presence of concomitant diseases in patients, and the underestimation of the long-term effects of radiation. Key words: female genital organs, radiation damage, radiodermatitis, radioepitheliitis, radiation rectitis, radiation cystitis.


Sign in / Sign up

Export Citation Format

Share Document