Antibiotic use during infectious episodes in the first 6 months of anticancer treatment-A Swedish cohort study of children aged 7-16 years

2017 ◽  
Vol 64 (7) ◽  
pp. e26397 ◽  
Author(s):  
M. af Sandeberg ◽  
E. Johansson ◽  
L. Wettergren ◽  
O. Björk ◽  
O. Hertting ◽  
...  
Keyword(s):  
Cohort Study ◽  
Antibiotic Use ◽  
Anticancer Treatment ◽  
Swedish Cohort

Variation in antibiotic use across intensive care units (ICU): A population-based cohort study in Ontario, Canada

2020 ◽  
Vol 41 (9) ◽  
pp. 1035-1041
Author(s):  
Erika Y. Lee ◽  
Michael E. Detsky ◽  
Jin Ma ◽  
Chaim M. Bell ◽  
Andrew M. Morris
Keyword(s):  
Cohort Study ◽  
Intensive Care ◽  
Intensive Care Units ◽  
Ventilatory Support ◽  
Severity Of Illness ◽  
Antibiotic Use ◽  
Patient Factors ◽  
Days Of Therapy ◽  
Level 3 ◽  
Level 2

AbstractObjectives:Antibiotics are commonly used in intensive care units (ICUs), yet differences in antibiotic use across ICUs are unknown. Herein, we studied antibiotic use across ICUs and examined factors that contributed to variation.Methods:We conducted a retrospective cohort study using data from Ontario’s Critical Care Information System (CCIS), which included 201 adult ICUs and 2,013,397 patient days from January 2012 to June 2016. Antibiotic use was measured in days of therapy (DOT) per 1,000 patient days. ICU factors included ability to provide ventilator support (level 3) or not (level 2), ICU type (medical-surgical or other), and academic status. Patient factors included severity of illness using multiple-organ dysfunction score (MODS), ventilatory support, and central venous catheter (CVC) use. We analyzed the effect of these factors on variation in antibiotic use.Results:Overall, 269,351 patients (56%) received antibiotics during their ICU stay. The mean antibiotic use was 624 (range 3–1460) DOT per 1,000 patient days. Antibiotic use was significantly higher in medical-surgical ICUs compared to other ICUs (697 vs 410 DOT per 1,000 patient days; P < .0001) and in level 3 ICUs compared to level 2 ICUs (751 vs 513 DOT per 1,000 patient days; P < .0001). Higher antibiotic use was associated with higher severity of illness and intensity of treatment. ICU and patient factors explained 47% of the variation in antibiotic use across ICUs.Conclusions:Antibiotic use varies widely across ICUs, which is partially associated with ICUs and patient characteristics. These differences highlight the importance of antimicrobial stewardship to ensure appropriate use of antibiotics in ICU patients.

Intercountry adopted children as young adults--A Swedish cohort study.

2003 ◽  
Vol 73 (2) ◽  
pp. 190-202 ◽  
Author(s):  
Frank Lindblad ◽  
Anders Hjern ◽  
B. Vinnerljung
Keyword(s):  
Young Adults ◽  
Cohort Study ◽  
Adopted Children ◽  
Swedish Cohort

scholarly journals Risk of suicide after suicide attempt according to coexisting psychiatric disorder: Swedish cohort study with long term follow-up

BMJ ◽  
2008 ◽  
Vol 337 (nov18 3) ◽  
pp. a2205-a2205 ◽  
Author(s):  
D. Tidemalm ◽  
N. Langstrom ◽  
P. Lichtenstein ◽  
B. Runeson
Keyword(s):  
Cohort Study ◽  
Suicide Attempt ◽  
Psychiatric Disorder ◽  
Long Term Follow Up ◽  
Swedish Cohort

scholarly journals Primary Care Consultations after Hospitalisation for Pneumonia: A Large Population-based Cohort Study

2020 ◽  
pp. BJGP.2020.0890
Author(s):  
Vadsala Baskaran ◽  
Fiona Pearce ◽  
Rowan H Harwood ◽  
Tricia McKeever ◽  
Wei Shen Lim
Keyword(s):  
Primary Care ◽  
Cohort Study ◽  
Large Population ◽  
Significant Proportion ◽  
Antibiotic Use ◽  
Population Based ◽  
Practice Research ◽  
Clinical Practice Research Datalink ◽  
Respiratory Disorder ◽  
The Impact

Background: Up to 70% of patients report ongoing symptoms four weeks after hospitalisation for pneumonia, and the impact on primary care is poorly understood. Aim: To investigate the frequency of primary care consultations after hospitalisation for pneumonia, and the reasons for consultation. Design: Population-based cohort study. Setting: UK primary care database of anonymised medical records (Clinical Practice Research Datalink, CPRD) linked to Hospital Episode Statistics (HES), England. Methods: Adults with the first ICD-10 code for pneumonia (J12-J18) recorded in HES between July 2002-June 2017 were included. Primary care consultation within 30 days of discharge was identified as the recording of any medical Read code (excluding administration-related codes) in CPRD. Competing-risks regression analyses were conducted to determine the predictors of consultation and antibiotic use at consultation; death and readmission were competing events. Reasons for consultation were examined. Results: Of 56,396 adults, 55.9% (n=31,542) consulted primary care within 30 days of discharge. The rate of consultation was highest within 7 days (4.7 per 100 person-days). The strongest predictor for consultation was a higher number of primary care consultations in the year prior to index admission (adjusted sHR 8.98, 95% CI 6.42-12.55). The commonest reason for consultation was for a respiratory disorder (40.7%, n=12,840), 12% for pneumonia specifically. At consultation, 31.1% (n=9,823) received further antibiotics. Penicillins (41.6%, n=5,753) and macrolides (21.9%, n=3,029) were the commonest antibiotics prescribed. Conclusion: Following hospitalisation for pneumonia, a significant proportion of patients consulted primary care within 30 days, highlighting the morbidity experienced by patients during recovery from pneumonia.

scholarly journals Cancer incidence in female laboratory employees: extended follow-up of a Swedish cohort study

2017 ◽  
Vol 74 (11) ◽  
pp. 823-826 ◽  
Author(s):  
Per Gustavsson ◽  
Tomas Andersson ◽  
Annika Gustavsson ◽  
Christina Reuterwall
Keyword(s):  
Cohort Study ◽  
Cancer Incidence ◽  
Swedish Cohort ◽  
Female Laboratory

scholarly journals Corrigendum to “Long-term mortality and morbidity among 30-day survivors after in-hospital cardiac arrests−A Swedish cohort study” [Resuscitation 124 (2018) 76–79]

Resuscitation ◽  
2018 ◽  
Vol 125 ◽  
pp. 144-148 ◽  
Author(s):  
Mahta Memar ◽  
Sammy-Jo Geara ◽  
Patrik Hjalmarsson ◽  
Anna Allberg ◽  
Mathilde Bouzereau ◽  
...  
Keyword(s):  
Cohort Study ◽  
Mortality And Morbidity ◽  
Swedish Cohort ◽  
Long Term Mortality
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