scholarly journals Is screening for abnormal ECG patterns justified in long-term follow-up of childhood cancer survivors treated with anthracyclines?

2016 ◽  
Vol 64 (3) ◽  
pp. e26243 ◽  
Author(s):  
Milanthy S. Pourier ◽  
Annelies M. C. Mavinkurve-Groothuis ◽  
Jacqueline Loonen ◽  
Jos P. M. Bökkerink ◽  
Nel Roeleveld ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Long Term Follow Up

scholarly journals Determining transition readiness in Swiss childhood cancer survivors – a feasibility study

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Maria Otth ◽  
Patrick Wechsler ◽  
Sibylle Denzler ◽  
Henrik Koehler ◽  
Katrin Scheinemann
Keyword(s):  
Health Care ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Self Management ◽  
Transition Readiness ◽  
Long Term Follow Up ◽  
Time Point

Abstract Background The successful transition of childhood cancer survivors (CCSs) from pediatric to adult long-term follow-up care is a critical phase, and determining the right time point can be challenging. We assessed the feasibility of the use of existing transition readiness tools in the context of the Swiss health care system, assessed partly transition readiness in Swiss CCSs, and compared our findings with Canadian CCSs for which these tools were originally developed. Methods We officially translated the Cancer Worry Scale (CWS) and Self-Management Skill Scale (SMSS) into German and integrated them into this cross-sectional study. We included CCSs attending the long-term follow-up (LTFU) clinic in the Division of Oncology-Hematology, Department of Pediatrics, Kantonsspital Aarau. We used descriptive statistics to describe transition readiness. Results We randomly recruited 50 CCSs aged ≥18 years at participation. The CCSs had a median CWS score of 62 (interquartile range 55–71), indicating a moderate level of cancer-related worry. Despite high self-management skills, some answers showed a dependency of CCSs on their parents. Our experience shows that the CWS and SMSS are easy for Swiss CCSs to use, understand, and complete. The interpretation of the results must take differences in health care systems between countries into account. Conclusions The translated CWS and SMSS are appropriate additional measures to assess transition readiness in CCSs. These scales can be used longitudinally to find the individual time point for transition and the completion by CCSs enables the health care team to individualize the transition process and to support the CCSs according to their individual needs.

The views of European clinicians on guidelines for long-term follow-up of childhood cancer survivors

2014 ◽  
Vol 62 (2) ◽  
pp. 322-328 ◽  
Author(s):  
Morven C. Brown ◽  
Gillian A. Levitt ◽  
Eva Frey ◽  
Edit Bárdi ◽  
Riccardo Haupt ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Long Term Follow Up

scholarly journals QOS-25A STUDY OF CHILDHOOD CANCER SURVIVORS' ENGAGEMENT WITH LONG-TERM FOLLOW-UP CARE

2016 ◽  
Vol 18 (suppl 3) ◽  
pp. iii150.4-iii150
Author(s):  
Nicky Thorp ◽  
Katherine Knighting ◽  
Lucy Bray ◽  
James Hayden ◽  
Laura Elder ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Follow Up Care ◽  
Long Term Follow Up

scholarly journals Risk stratification of childhood cancer survivors necessary for evidence-based clinical long-term follow-up

2017 ◽  
Vol 117 (11) ◽  
pp. 1723-1731 ◽  
Author(s):  
Clare Frobisher ◽  
◽  
Adam Glaser ◽  
Gill A Levitt ◽  
David J Cutter ◽  
...  
Keyword(s):  
Risk Stratification ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Evidence Based ◽  
Long Term Follow Up

The impact of long-term follow-up care for childhood cancer survivors: A systematic review

2017 ◽  
Vol 114 ◽  
pp. 131-138 ◽  
Author(s):  
Christina Signorelli ◽  
Claire E. Wakefield ◽  
Joanna E. Fardell ◽  
W. Hamish B. Wallace ◽  
Eden G. Robertson ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Follow Up Care ◽  
Long Term Follow Up ◽  
The Impact

Long-term follow-up of childhood cancer survivors in the Murcia Region: Preferences and attitudes of Primary Care professionals

2015 ◽  
Vol 83 (4) ◽  
pp. 264-271 ◽  
Author(s):  
A. Cárceles-Álvarez ◽  
J.A. Ortega-García ◽  
J.L. Fuster-Soler ◽  
G.A. Rivera-Pagán ◽  
M. Bermúdez-Cortés ◽  
...  
Keyword(s):  
Primary Care ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Long Term Follow Up ◽  
Primary Care Professionals

Characteristics of childhood cancer survivors who attend long-term follow-up (LTFU) clinic.

2011 ◽  
Vol 29 (15_suppl) ◽  
pp. 9566-9566
Author(s):  
K. Devine ◽  
J. R. Andolina ◽  
N. Murray ◽  
G. R. Morrow ◽  
O. J. Sahler
Keyword(s):  
Cancer Survivors ◽  
Childhood Cancer ◽  
Childhood Cancer Survivors ◽  
Long Term Follow Up

Impact of using volumetric dosimetry to screen childhood cancer survivors for radiation-related late effects.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 12066-12066
Author(s):  
Sally Cohen-Cutler ◽  
Cameron Kaplan ◽  
Arthur Olch ◽  
Kenneth Wong ◽  
Jemily Malvar ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Childhood Cancer ◽  
Late Effects ◽  
Pure Tone ◽  
Childhood Cancer Survivors ◽  
Cancer Type ◽  
Screening Practices ◽  
Long Term Follow Up

12066 Background: Late effects screening guidelines for survivors of childhood cancer treated with radiation therapy currently use irradiated regions (IR) rather than volumetric dosimetry (VD), which more precisely identifies organs-at-risk (OAR). We recently showed that VD reduced mean number of recommended screening diagnostic imaging studies and procedures by 37.0% per patient (p<0.001).1 Here we have incorporated chemotherapy and refined volumetric dosimetry dose thresholds. Methods: This was a cross-sectional cohort study of patients (n=132) treated for cancer using computerized tomography-planned irradiation at Children’s Hospital Los Angeles from 2000-2016. For each patient, both VD and IR methods were used to determine radiation exposure to the cochlea, heart, lung, breast, and colon. Dose thresholds for VD were based on those supplied in the Children’s Oncology Group (COG) Long-Term Follow-Up Guidelines. Relevant chemotherapy exposures were recorded. Under each method, COG Long-Term Follow-Up Guidelines were applied to determine potential chemotherapy- and radiation-related late effects and their correlative screening practices (complete audiologic evaluation, pure tone audiometry, mammogram, breast MRI, echocardiogram, pulmonary functions test, and/or colonoscopy). Identified OAR were compared using Exact McNemar’s test. Total numbers of screening practices were computed using VD and IR and compared. Results: Median age at end of treatment was 10.6 years (range 1.4-20.4). The most frequent cancer type was brain tumor (45%), followed by bone and soft tissue tumor (39%) and leukemia/lymphoma (16%). Head/brain was the most commonly irradiated region (61%), followed by abdomen (22%). Anthracyclines were received by 25% of patients at < 250 mg/m2 and by 16% at ≥ 250 mg/m2. With use of VD, fewer patients were flagged for screening for each organ of interest: cochlea (-21.3%, p<0.001), heart (-22.5%, p<0.001), lung (-13.8%, p=0.219), breast (-25%, p=0.625), colon (-51.9%, p<0.001). Over the lifetime of this cohort, use of VD resulted in recommendations for 1,333 fewer pure tone audiometric tests (-21.5%), 9 fewer complete audiologic evaluations (-16.1%), 4 fewer pulmonary function tests (-13.8%), 112 fewer mammograms (-25.0%) and breast MRIs (-25.0%), 349 fewer echocardiograms (-16.1%), and 275 fewer colonoscopies (-51.9%). Conclusions: Use of VD rather than IR significantly reduces guideline-based screening for radiation-related late effects in long-term childhood cancer survivors. This work forms the basis for a comparative cost-effectiveness analysis of these two approaches. (1) Cohen-Cutler et al, Cancer Medicine, 2020.

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