Smoking, Binge Drinking, and Drug Use Among Childhood Cancer Survivors: A Meta-Analysis

2016 ◽  
Vol 63 (7) ◽  
pp. 1254-1263 ◽  
Author(s):  
Stacey Marjerrison ◽  
Eleanor Hendershot ◽  
Brianna Empringham ◽  
Paul C. Nathan
Keyword(s):  
Drug Use ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Binge Drinking ◽  
Meta Analysis ◽  
Childhood Cancer Survivors

scholarly journals Exercise Interventions and Cardiovascular Health in Childhood Cancer: A Meta-analysis

2020 ◽  
Vol 41 (03) ◽  
pp. 141-153 ◽  
Author(s):  
Javier S. Morales ◽  
Pedro L. Valenzuela ◽  
Alba M. Herrera-Olivares ◽  
Antonio Baño-Rodrigo ◽  
Adrián Castillo-García ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Meta Analysis ◽  
Childhood Cancer Survivors ◽  
Left Ventricular ◽  
Mean Difference ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Exercise Interventions

AbstractThis study analyzed the effects of physical exercise interventions on cardiovascular endpoints in childhood cancer survivors. Relevant articles were systematically searched in PubMed, CINAHL, and Web of Science databases (since inception to 11th September 2019). We performed a meta-analysis (random effects) to determine the mean difference (expressed together with 95% confidence intervals) between pre- and post-intervention values for those cardiovascular endpoints reported in more than three studies. Twenty-seven studies (of which 16 were controlled studies) comprising 697 participants were included. Only three studies reported adverse events related to exercise interventions. Exercise resulted in an increased performance on the 6-minute walk distance test (mean difference=111 m, 95% confidence interval=39–183, p=0.003) and a non-significant trend (mean difference=1.97 ml∙kg−1∙min−1, 95% confidence interval=−0.12–4.06, p=0.065) for improvement in peak oxygen uptake. Furthermore, left ventricular ejection fraction was preserved after exercise interventions (mean difference=0.29%, 95% confidence interval=−1.41–1.99, p=0.738). In summary, exercise interventions might exert a cardioprotective effect in childhood cancer survivors by improving – or attenuating the decline of – physical capacity and cardiovascular function. Further studies, particularly randomized controlled trials, are needed to confirm these benefits.

Meta-analysis of second cancer risk after radiotherapy among childhood cancer survivors

2011 ◽  
Vol 146 (1-3) ◽  
pp. 263-267 ◽  
Author(s):  
K. Doi ◽  
M. N. Mieno ◽  
Y. Shimada ◽  
H. Yonehara ◽  
S. Yoshinaga
Keyword(s):  
Cancer Risk ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Meta Analysis ◽  
Childhood Cancer Survivors ◽  
Second Cancer ◽  
Second Cancer Risk

Alcohol consumption and binge drinking in young adult childhood cancer survivors

2011 ◽  
Vol 58 (2) ◽  
pp. 256-264 ◽  
Author(s):  
Cornelia E. Rebholz ◽  
Claudia E. Kuehni ◽  
Marie-Pierre F. Strippoli ◽  
Corina S. Rueegg ◽  
Gisela Michel ◽  
...  
Keyword(s):  
Young Adult ◽  
Alcohol Consumption ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Binge Drinking ◽  
Childhood Cancer Survivors

scholarly journals Serum Anti-Müllerian Hormone Levels and Risk of Premature Ovarian Insufficiency in Female Childhood Cancer Survivors: Systematic Review and Network Meta-Analysis

Cancers ◽  
2021 ◽  
Vol 13 (24) ◽  
pp. 6331
Author(s):  
Marco Torella ◽  
Gaetano Riemma ◽  
Pasquale De Franciscis ◽  
Marco La Verde ◽  
Nicola Colacurci
Keyword(s):  
Systematic Review ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Ovarian Reserve ◽  
Meta Analysis ◽  
Childhood Cancer Survivors ◽  
Premature Ovarian Insufficiency ◽  
Control Group ◽  
Ovarian Insufficiency ◽  
Increased Risk

Background: Female childhood cancer survivors (CCS) might have impaired ovarian reserves, especially after alkylating agents or radiotherapy. The purpose of this systematic review and network meta-analysis is to evaluate the role of serum anti-Müllerian hormone (AMH) for ovarian reserve screening and the risk of premature ovarian insufficiency (POI) according to the subtype of childhood cancer. (2) Methods: PRISMA-NMA guidelines were followed. We carried out a network meta-analysis based on a random effects model for mixed multiple treatment comparisons to rank childhood cancers effects on fertility by surface under the cumulative ranking curve (SUCRA). Studies were selected only if they had an age-matched control group. Quality assessment was performed using Newcastle–Ottawa Scale. The co-primary outcomes were mean AMH levels and the incidence of POI. (3) Results: A total of 8 studies (1303 participants) were included. Women treated for a neuroblastoma during infancy were more likely to be ranked first for impaired AMH levels (SUCRA = 65.4%), followed by mixed CCS (SUCRA = 29.6%). The greatest rates of POI were found in neuroblastoma survivors (SUCRA = 42.5%), followed by acute lymphoid leukemia (SUCRA = 26.3%) or any other neoplasia (SUCR A= 20.5%). (4) Conclusions: AMH represents a trustworthy approach for ovarian reserve screening. Direct and indirect comparisons found no differences in mean AMH levels and POI risk between subtypes of CCS and healthy controls. SUCRA analysis showed that female neuroblastoma survivors were more at risk for reduced serum AMH levels and increased risk of POI.

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