Rare malignant pediatric tumors registered in the German Childhood Cancer Registry 2001-2010

2014 ◽  
Vol 61 (7) ◽  
pp. 1202-1209 ◽  
Author(s):  
Ines B. Brecht ◽  
Claudia Bremensdorfer ◽  
Dominik T. Schneider ◽  
Michael C. Frühwald ◽  
Sonja Offenmüller ◽  
...  
Keyword(s):  
Childhood Cancer ◽  
Cancer Registry ◽  
Pediatric Tumors ◽  
German Childhood Cancer Registry

Neuroblastoma metastatic to the central nervous system: Survival analyses from the German Childhood Cancer Registry and the literature.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 10555-10555
Author(s):  
Frank Berthold ◽  
Marc Hömberg ◽  
Ole Baadsgaard
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Childhood Cancer ◽  
Cancer Registry ◽  
Natural Course ◽  
Curative Intent ◽  
Term Survival ◽  
The Central Nervous System ◽  
Inclusive Analysis ◽  
German Childhood Cancer Registry

10555 Background: Therapeutic innovation has resulted in an overall decline in childhood neuroblastoma (NB) mortality; however, metastatic NB to the central nervous system (CNS NB), which has emerged as a sanctuary site for NB metastases, remains difficult to treat and is typically fatal. The objective of this study was to describe the natural course of CNS NB. Methods: Data were sourced from a custom query of the German Childhood Cancer Registry (GCCR) and from the literature. Survival statistics were prepared from a diverse, thus generalizable, pool of CNS NB patients. Data are presented as secondary event-free and overall survival (EFS and OS) after diagnosis of first CNS recurrence from initial high-risk NB. Results: The GCCR query identified 85 patients with CNS NB diagnosed from 1990–2010, including 57 with isolated CNS disease. The median (95% confidence) EFS and OS times were 2.6 (1.5–3.8) and 4.7 (2.1–7.2) months, respectively, for all CNS NB patients, and 2.8 (1.4–4.1) and 6.8 (2.1–11.5) months, respectively, for isolated CNS NB patients. Secondary OS at 12, 18, and 36 months was 29.4%, 18.8%, and 8.2%, respectively, for all CNS NB patients, and 35.1%, 22.8%, and 12.3%, respectively, for isolated CNS NB patients. Thirteen publications were selected with 83 patients treated from 1979–2013. In addition to an inclusive analysis, a restricted analysis was performed, excluding patients who did not receive therapy with curative intent, to assess survival after therapeutic intervention. Median OS (95% confidence) was 5.6 (3.0–8.0) and 8.7 (5.8–11.0) months in the inclusive and restricted analyses, respectively. The proportion of patients surviving 12, 18, and 36 months at reporting were 24%, 12%, and 3.6%, respectively, for the inclusive population, and 33%, 17%, and 5%, respectively, for the restricted population. Conclusions: An assessment of the natural course of CNS NB from two sources arrived at similar conclusions with respect to overall and long-term survival. In general, median secondary OS is < 6 months and < 10% of patients survive 36 months. The findings were consistent across geographic regions and have not changed appreciably in 4 decades.

The Cohort of Long-term Survivors at the German Childhood Cancer Registry

2008 ◽  
Vol 220 (06) ◽  
pp. 371-377 ◽  
Author(s):  
D. Debling ◽  
C. Spix ◽  
M. Blettner ◽  
J. Michaelis ◽  
P. Kaatsch
Keyword(s):  
Childhood Cancer ◽  
Cancer Registry ◽  
Long Term Survivors ◽  
German Childhood Cancer Registry

Strategy for Long-Term Surveillance at the German Childhood Cancer Registry - an Update

2011 ◽  
Vol 223 (03) ◽  
pp. 159-164 ◽  
Author(s):  
D. Grabow ◽  
C. Spix ◽  
M. Blettner ◽  
P. Kaatsch
Keyword(s):  
Childhood Cancer ◽  
Cancer Registry ◽  
German Childhood Cancer Registry

scholarly journals Cancer patterns among children of Turkish descent in Germany: A study at the German Childhood Cancer Registry

2008 ◽  
Vol 8 (1) ◽  
Author(s):  
Jacob Spallek ◽  
Claudia Spix ◽  
Hajo Zeeb ◽  
Peter Kaatsch ◽  
Oliver Razum
Keyword(s):  
Childhood Cancer ◽  
Cancer Registry ◽  
German Childhood Cancer Registry

scholarly journals Implementing Yogyakarta Pediatric Cancer Registry for 16 years

2019 ◽  
Vol 59 (4) ◽  
pp. 188-94
Author(s):  
Sri Mulatsih ◽  
Adnina Hariningrum ◽  
Ignatius Purwanto ◽  
Rizki Oktasari
Keyword(s):  
Childhood Cancer ◽  
Cancer Registry ◽  
Pediatric Cancer ◽  
Lymphoblastic Leukemia ◽  
Myeloproliferative Disorders ◽  
Cancer Registries ◽  
Clinical Aspects ◽  
Cancer Registry Data ◽  
Kaplan Meier ◽  
Standard Risk

Background A hospital-based cancer registry can be used as a guide to decision-making. Considering the limited cancer registry data in the population, the Yogyakarta Pediatric Cancer Registry (YPCR) is one of the pioneers of hospital-based pediatric cancer registries in Indonesia. The YPCR was started in 2000 in Dr. Sardjito Hospital. Objective To describe the characteristics of childhood cancer and the outcomes by analyzing overall survival (OS) and event-free survival (EFS) based on data from Yogyakarta Pediatric Cancer Registry. Methods Data were collected from the YPCR for the period of 2000 to 2016. Childhood cancers were classified into 12 groups based on the 3rd edition International Classification for Childhood Cancer (ICCC). Incidence, frequency, and distribution of cases were grouped by sex, age, and patients’ place of residence. Incidence was further analyzed using SPSS software. Kaplan-Meier test was used to analyze OS and EFS. Results Within the study period, 2,441 children aged 0-18 years were diagnosed with cancer. The highest incidence was found in the 1-5-year age group. The most common diagnoses found were leukemia, myeloproliferative disorders, and myelodysplastic disease (58%); lymphoma and reticuloendothelial neoplasm (8%); retinoblastoma (6%); soft tissue and other extra-osseous sarcomas (5%); as well as neuroblastoma and other peripheral nervous cell tumors (5%). The OSs of acute lymphoblastic leukemia (ALL), high risk ALL (HR-ALL), and standard risk (SR-ALL) were 31.8%, 18.5%, and 43.9%, respectively. The EFSs of ALL, HR-ALL, and SR-ALL were 23.9%, 14.7%, and 32.4%, respectively. For solid tumors, the OS was 13.7% and EFS was 6.4%. Conclusion The number of new cases of childhood cancer has increased in the last few years. The Yogyakarta Pediatric Cancer Registry (YPCR), which serves as a hospital-based pediatric cancer registry, has an important role to evaluate clinical and non-clinical aspects of childhood cancer.

scholarly journals Overall and Event Free Survival of Childhood Cancer in India in the 21st century: Report from a Hospital Based Cancer Registry

2018 ◽  
Vol 3 (3) ◽  
pp. S13
Author(s):  
Ramandeep Arora ◽  
Arun Adhana ◽  
Rashi Tripathi ◽  
Prachi Jain ◽  
Mansi Sachdev
Keyword(s):  
Childhood Cancer ◽  
Cancer Registry ◽  
21St Century ◽  
Event Free Survival ◽  
Free Survival
Sign in / Sign up

Export Citation Format

Share Document