De-escalation of therapy for pediatric medulloblastoma: Trade-offs between quality of life and survival

2014 ◽  
Vol 61 (7) ◽  
pp. 1300-1304 ◽  
Author(s):  
Natalie Henrich ◽  
Carlo A. Marra ◽  
Louise Gastonguay ◽  
Donald Mabbott ◽  
David Malkin ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Trade Offs ◽  
Pediatric Medulloblastoma

Societal preferences in the treatment of pediatric medulloblastoma: Balancing risk of death and quality of life

2016 ◽  
Vol 64 (6) ◽  
pp. e26340 ◽  
Author(s):  
Amir Khakban ◽  
Tima Mohammadi ◽  
Larry D. Lynd ◽  
Don Mabbott ◽  
Eric Bouffet ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Of Death ◽  
Pediatric Medulloblastoma ◽  
Societal Preferences

scholarly journals Design trade-offs in cultures of participation: empowering end users to improve their quality of life

2019 ◽  
Vol 39 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Gerhard Fischer ◽  
Daniela Fogli ◽  
Anders Mørch ◽  
Antonio Piccinno ◽  
Stefano Valtolina
Keyword(s):  
Quality Of Life ◽  
End Users ◽  
Trade Offs

Combining components of quality of life to increase precision and evaluate trade-offs

2001 ◽  
Vol 20 (21) ◽  
pp. 3231-3249 ◽  
Author(s):  
T. Lumley ◽  
R. J. Simes ◽  
V. Gebski ◽  
H. M. Hudson
Keyword(s):  
Quality Of Life ◽  
Trade Offs

scholarly journals Using Decision Analysis to Understand the Indications for Unilateral Hand Transplantation

Hand ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. 450-455 ◽  
Author(s):  
Brett McClelland ◽  
Christine B. Novak ◽  
Steven Hanna ◽  
Steven J. McCabe
Keyword(s):  
Quality Of Life ◽  
Decision Tree ◽  
Decision Analysis ◽  
Upper Extremity ◽  
Functional Recovery ◽  
High Probability ◽  
Improve Quality ◽  
Hand Transplantation ◽  
Trade Offs

Background: Upper extremity transplantation has been performed to improve quality of life, the benefit which must be traded off for the risk created by life-long immunosuppression. We believe the process of decision analysis is well suited to improve our understanding of these trade-offs. Method: We created a decision tree to include a branch point to illustrate the expected recovery of useful function in the transplant, using the best estimates for utility and probability that exist. Results: Our model revealed that when the probability of achieving a good result, graded as Chen level one or two is greater than 73%, transplantation is preferred over no transplantation. The decision is sensitive to the probability of major complications and the utility of a transplanted limb with minimal function. Conclusions: The results of this analysis show that under some circumstances given a high probability of satisfactory functional recovery, unilateral hand transplantation can be justified.

scholarly journals Trade-Offs in Quality-of-Life Assessment Between the Modified Rankin Scale and Neuro-QoL Measures

2020 ◽  
Vol 23 (10) ◽  
pp. 1366-1372
Author(s):  
Robert L. Askew ◽  
Carmen E. Capo-Lugo ◽  
Rajbeer Sangha ◽  
Andrew Naidech ◽  
Shyam Prabhakaran
Keyword(s):  
Quality Of Life ◽  
Life Assessment ◽  
Modified Rankin Scale ◽  
Quality Of Life Assessment ◽  
Trade Offs
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