A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium

Alexandra P. Zorzi; Mark Bernstein; Yvan Samson; Donna A. Wall; Sunil Desai; Darcy Nicksy; Nancy Wainman; Elizabeth Eisenhauer; Sylvain Baruchel

doi:10.1002/pbc.24694

A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium

Pediatric Blood & Cancer ◽

10.1002/pbc.24694 ◽

2013 ◽

Vol 60 (11) ◽

pp. 1868-1874 ◽

Cited By ~ 22

Author(s):

Alexandra P. Zorzi ◽

Mark Bernstein ◽

Yvan Samson ◽

Donna A. Wall ◽

Sunil Desai ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Pediatric Patients ◽

Deacetylase Inhibitor

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Faculty of 1000 evaluation for A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.718050520.793482822 ◽

2013 ◽

Author(s):

Burton Eisenberg

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Pediatric Patients ◽

Deacetylase Inhibitor

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Faculty of 1000 evaluation for A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.718050520.793482405 ◽

2013 ◽

Author(s):

Daniel Indelicato

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Pediatric Patients ◽

Deacetylase Inhibitor

Download Full-text

Faculty of 1000 evaluation for A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.718050520.793483440 ◽

2013 ◽

Author(s):

Antoine Italiano

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Pediatric Patients ◽

Deacetylase Inhibitor

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344 A Phase I Study of Histone Deacetylase Inhibitor, SB939, in Pediatric Patients with Refractory Solid Tumors

European Journal of Cancer ◽

10.1016/s0959-8049(12)72142-1 ◽

2012 ◽

Vol 48 ◽

pp. 105

Author(s):

A.P. Zorzi ◽

M. Bernstein ◽

Y. Samson ◽

D.A. Wall ◽

S. Desai ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Pediatric Patients ◽

Deacetylase Inhibitor

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A Phase I Study of Quisinostat (JNJ-26481585), an Oral Hydroxamate Histone Deacetylase Inhibitor with Evidence of Target Modulation and Antitumor Activity, in Patients with Advanced Solid Tumors

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-13-0312 ◽

2013 ◽

Vol 19 (15) ◽

pp. 4262-4272 ◽

Cited By ~ 63

Author(s):

Balaji Venugopal ◽

Richard Baird ◽

Rebecca S. Kristeleit ◽

Ruth Plummer ◽

Richard Cowan ◽

...

Keyword(s):

Antitumor Activity ◽

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Advanced Solid Tumors ◽

Deacetylase Inhibitor

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Phase I study of chidamide (CS055/HBI-8000), a new histone deacetylase inhibitor, in patients with advanced solid tumors and lymphomas

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-012-1847-5 ◽

2012 ◽

Vol 69 (6) ◽

pp. 1413-1422 ◽

Cited By ~ 51

Author(s):

Mei Dong ◽

Zhi-Qiang Ning ◽

Pu-Yuan Xing ◽

Jia-Lian Xu ◽

Hai-Xiang Cao ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Advanced Solid Tumors ◽

Deacetylase Inhibitor

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Abstract 1172: Phase I study of histone deacetylase inhibitor belinostat in combination with warfarin in patients with solid tumors or hematological malignancies.

10.1158/1538-7445.am2013-1172 ◽

2013 ◽

Cited By ~ 2

Author(s):

Neeraj Agarwal ◽

Mark L. Wade ◽

Julia Batten ◽

Cynthia Davidson ◽

Show-Li Sun ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Hematological Malignancies ◽

Deacetylase Inhibitor

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First-in-human, Pharmacokinetic and Pharmacodynamic Phase I Study of Resminostat, an Oral Histone Deacetylase Inhibitor, in Patients with Advanced Solid Tumors

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-13-0735 ◽

2013 ◽

Vol 19 (19) ◽

pp. 5494-5504 ◽

Cited By ~ 34

Author(s):

André T. Brunetto ◽

Joo Ern Ang ◽

Rohit Lal ◽

David Olmos ◽

L. Rhoda Molife ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Advanced Solid Tumors ◽

Deacetylase Inhibitor ◽

Human Pharmacokinetic

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586 Phase I study of pan-histone deacetylase inhibitor abexinostat in combination with cisplatin in patients with advanced solid tumors

European Journal of Cancer ◽

10.1016/s0959-8049(14)70712-9 ◽

2014 ◽

Vol 50 ◽

pp. 189

Author(s):

M. Campone ◽

N. Isambert ◽

R. Sabatier ◽

H. Castanie ◽

S. Zanetta ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Advanced Solid Tumors ◽

Deacetylase Inhibitor

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Phase I study of the histone deacetylase inhibitor entinostat in combination with 13-cis retinoic acid in patients with solid tumours

British Journal of Cancer ◽

10.1038/bjc.2011.527 ◽

2011 ◽

Vol 106 (1) ◽

pp. 77-84 ◽

Cited By ~ 101

Author(s):

R Pili ◽

B Salumbides ◽

M Zhao ◽

S Altiok ◽

D Qian ◽

...

Keyword(s):

Retinoic Acid ◽

Phase I ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Solid Tumours ◽

Deacetylase Inhibitor

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