A prospective observational study of IVC filters in pediatric patients

2008 ◽  
Vol 51 (4) ◽  
pp. 517-520 ◽  
Author(s):  
Leslie Raffini ◽  
Anne Marie Cahill ◽  
Jeffrey Hellinger ◽  
Catherine Manno
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Pediatric Patients ◽  
Ivc Filters

scholarly journals Hypocalcemia following Neridronate Administration in Pediatric Patients with Osteogenesis Imperfecta: A Prospective Observational Study

2020 ◽  
Vol 09 (02) ◽  
pp. 093-100 ◽  
Author(s):  
Evelina Maines ◽  
Elisa Tadiotto ◽  
Grazia Morandi ◽  
Michela Fedrizzi ◽  
Rossella Gaudino ◽  
...  
Keyword(s):  
Vitamin D ◽  
Observational Study ◽  
Osteogenesis Imperfecta ◽  
Prospective Observational Study ◽  
Pediatric Patients ◽  
Pediatric Population ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Vitamin D Levels ◽  
D Values

AbstractThe use of intravenous bisphosphonates has been linked to hypocalcemia both in children and adults with osteogenesis imperfecta (OI). The aims of this study were: (1) to investigate the incidence of hypocalcemia in the first 48 hours (T48) after neridronate infusion in a pediatric population with OI and (2) to assess any correlation between the baseline values of calcium, vitamin D (25-hydroxyvitamin D) and bone turnover markers, and the postinfusion calcium values. We conducted a prospective observational study on 37 pediatric patients. All patients were treated with a single infusion of neridronate at a dose of 1 to 2 mg/kg. The study provided two postinfusion reassessments: 24 hours (T24) and T48 after neridronate administration. Hypocalcemia was observed in 11% of patients at T24 and in 50% of patients at T48 from neridronate infusion. We observed a positive linear correlation between the baseline vitamin D values and postinfusion calcium values, both at baseline and at T24 and T48. Hypocalcemia was mild and asymptomatic in all cases. Postinfusion calcium levels were related to baseline vitamin D levels. Consequently, low vitamin D levels should be considered a significant risk factor for hypocalcemia and should be carefully investigated and treated before neridronate infusion.

scholarly journals Off-Label Medicine Use in Pediatric Inpatients: A Prospective Observational Study at a Tertiary Care Hospital in India

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Mohd Masnoon Saiyed ◽  
Tarachand Lalwani ◽  
Devang Rana
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Pediatric Patients ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Quality Data ◽  
Care Hospital ◽  
Off Label Use ◽  
Off Label ◽  
Label Use

Background. In the absence of standard pediatric prescribing information, clinicians often use medicines in an off-label way. Many studies have been published across the globe reporting different rates of off-label use. There is currently no study based on Indian drug formulary.Methods. The prospective observational study included pediatric patients in ages between 0 and 12 years admitted in a tertiary care hospital. Off-label use was assessed using the National Formulary of India (NFI). Predictors of off-label use were determined by logistic regression.Results. Of the 1645 medications prescribed, 1152 (70%) were off-label based on 14 possible off-label categories. Off-label medicines were mainly due to dose difference and use in restricted age limits as indicated in NFI. Respiratory medicines (82%), anti-infectives (73%), and nervous system medicines (53%) had higher off-label use. Important predictors of off-label prescribing were pediatric patients in age of 0 to 2 years (OR 1.68, 95% CI;P<0.001) and hospital stay of six to 10 days (OR 1.91, 95% CI;P<0.001).Conclusion. Off-label prescribing is common among pediatric patients. There is need to generate more quality data on the safety and efficacy of off-label medicines to rationalize pediatric pharmacotherapy.

scholarly journals Treatment outcome and associated factors of bacterial meningitis at pediatric wards of southwestern Ethiopian hospital: a prospective observational study

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Firomsa Bekele ◽  
Anuwar Ahmed ◽  
Abas Kedir ◽  
Tadesse Sheleme
Keyword(s):  
Treatment Outcome ◽  
Bacterial Meningitis ◽  
Observational Study ◽  
General Hospital ◽  
Prospective Observational Study ◽  
Pediatric Patients ◽  
Acute Bacterial Meningitis ◽  
Good Treatment Outcome ◽  
Poor Treatment ◽  
Poor Treatment Outcome

Abstract Background Meningitis is a common infectious cause of morbidity and mortality in pediatric age-groups. Acute bacterial meningitis is considered a medical emergency, because it is a life-threatening infection that requires immediate treatment. Therefore the study was aimed to assess the magnitude and predictors of poor treatment outcome among pediatric patients admitted to Bedele General Hospital. Methods A prospective observational study was conducted at pediatric wards of Bedele General Hospital from February 12, 2020 to August 11, 2020. Lumbar puncture, in the absence of contraindications, was performed under aseptic conditions for all patients with suspected bacterial meningitis to collect cerebrospinal fluid specimen. Multivariable logistic regression was used to determine the predictors of poor treatment outcome. Result Of the 196 pediatric patients involved, 112(57.1%) were male and the mean and standard deviation of their age was 6.09 ± 4.46. Regarding to their clinical profile, a total of 101(51.5%) were completely immunized and 115(58.7%) were given corticosteroid during their treatment. In our study the most frequently occurred clinical manifestation of meningitis was fever 164(83.67%), neck rigidity149 (76.02%), and irritability 122(62.24%). Regarding to their pharmacotherapy, the most commonly prescribed antibiotics were Ampicillin 104(24.82%), and Gentamycin 102(24.34%). The magnitude of good treatment outcome was 132(67.35%) whereas 64(32.65%) were poorly controlled. The presence of comorbidity (AOR = 3.64, 95CI%:1.83–7.23,P = < 0.001),corticosteroid use (AOR = 2.37, 95CI%:1.17–4.81,P = 0.017) and oxygen administration (AOR = 3.12, 95CI%: 1.34–7.25, P = 0.008) was a predictor of meningitis treatment outcome. Conclusion The treatment outcome of meningitis was good in of two-third of the patients. It was found that the presence of comorbidity, the administration of oxygen and use of corticosteroid was predictors of the treatment outcomes of bacterial meningitis in children. Therefore, in patients with these factors, appropriate meningitis treatment should be encouraged and locally applicable treatment guidelines should be prepared to improve patient outcome. Finally, the meningitis patients should be given corticosteroid and oxygen as treatment and special attention should be given for patients having co-morbidities.

scholarly journals TO ASSESS THE ACCURACY OF CLINICAL PALLOR IN PEDIATRIC PATIENTS DIAGNOSED OF ANEMIA IN NORTH BIHAR REGION: AN OBSERVATIONAL STUDY.

2020 ◽  
Vol 4 (8) ◽  
Author(s):  
Satyendra Paswan ◽  
Nagendra Prasad Gupta ◽  
Shaantanu Kumar
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Pediatric Patients ◽  
Moderate Degree ◽  
Severe Anemia ◽  
Clinical Criteria ◽  
Medical College ◽  
Moderate Anemia

Aim: to assess the accuracy of clinical pallor in pediatric patients diagnosed of anemia. Material and Methods: The present prospective observational study was conducted in the Department of Pediatrics Darbhanga Medical College and Hospital, Darbhanga, Bihar, India from August 2019 to March 2020 among 200 anemic children attained the age between 6 months to 5 years. Blood was drawn by venepuncture and hemoglobin estimation was done by cyanmethemoglobin method. Anemia was diagnosed when hemoglobin was less than 11g/dl. Results: anemia is less common among infants aged below 12 months. The moderate anemia was best detected by using palm pallor or pallor of the nail beds (sensitivity 92-95%), while conjunctival pallor was least useful (sensitivity 82%).   Conclusion: This study demonstrates that clinical criteria can be used to identify children with anemia of moderate degree who need treatment with iron. Moderate anemia is associated with morbidity that may progress to severe anemia and death unless prevented by treatment with iron. Keywords: Anemia, Accuracy, Pallor, Infants

Adverse Drug Reactions in Hospitalized Pediatric Patients: A Prospective Observational Study

2016 ◽  
Vol 83 (5) ◽  
pp. 414-419 ◽  
Author(s):  
J. Kurian ◽  
J. Mathew ◽  
K. Sowjanya ◽  
K. R. K. Chaitanya ◽  
M. Ramesh ◽  
...  
Keyword(s):  
Observational Study ◽  
Adverse Drug Reactions ◽  
Prospective Observational Study ◽  
Pediatric Patients ◽  
Drug Reactions

Bispectral Index monitoring of propofol anesthesia in pediatric patients with hydrocephalus. A prospective observational study

2014 ◽  
Vol 24 (11) ◽  
pp. 1190-1192 ◽  
Author(s):  
Ashraf A. Dahaba ◽  
Han Lin ◽  
Xue Fei Ye ◽  
Jian Lin ◽  
Nu Zhang ◽  
...  
Keyword(s):  
Observational Study ◽  
Bispectral Index ◽  
Prospective Observational Study ◽  
Pediatric Patients ◽  
Bispectral Index Monitoring
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