Long-term follow-up of survivors of childhood cancer in the UK

2004 ◽  
Vol 42 (2) ◽  
pp. 161-168 ◽  
Author(s):  
Aliki Taylor ◽  
Mike Hawkins ◽  
Annie Griffiths ◽  
Helena Davies ◽  
Carolyn Douglas ◽  
...  
Keyword(s):  
Childhood Cancer ◽  
Long Term Follow Up ◽  
The Uk ◽  
Survivors Of Childhood Cancer

Long term follow-up of survivors of childhood cancer: summary of updated SIGN guidance

BMJ ◽  
2013 ◽  
Vol 346 (mar27 1) ◽  
pp. f1190-f1190 ◽  
Author(s):  
W. H. B. Wallace ◽  
L. Thompson ◽  
R. A. Anderson ◽  
Keyword(s):  
Childhood Cancer ◽  
Long Term Follow Up ◽  
Survivors Of Childhood Cancer

scholarly journals Use of Chronic Prescription Medications and Prevalence of Polypharmacy in Survivors of Childhood Cancer

2021 ◽  
Vol 11 ◽  
Author(s):  
Celeste L. Y. Ewig ◽  
Yi Man Cheng ◽  
Hoi Shan Li ◽  
Jasper Chak Ling Wong ◽  
Alex Hong Yu Cho ◽  
...  
Keyword(s):  
Childhood Cancer ◽  
Medication Use ◽  
Cns Tumors ◽  
Chronic Medication ◽  
Factors Associated ◽  
Cranial Radiation ◽  
Long Term Follow Up ◽  
Survivors Of Childhood Cancer

BackgroundAs survivors of childhood cancer age, development of cancer treatment-related chronic health conditions often occur. This study aimed to describe the pattern of chronic prescription medication use and identify factors associated with polypharmacy among survivors of childhood cancer.MethodsThis was a retrospective study conducted at the pediatric oncology long-term follow-up clinic in Hong Kong. Eligible subjects included survivors who were (1) diagnosed with cancer before 18 years old, (2) were at least 3 years post-cancer diagnosis and had completed treatment for at least 30 days, and (3) receiving long-term follow-up care at the study site between 2015 and 2018. Dispensing records of eligible survivors were reviewed to identify medications taken daily for ≥30 days or used on an “as needed” basis for ≥6 months cumulatively within the past 12-month period. Polypharmacy was defined as the concurrent use of ≥5 chronic medications. Multivariable log-binomial modeling was conducted to identify treatment and clinical factors associated with medication use pattern and polypharmacy.ResultsThis study included 625 survivors (mean current age = 17.9 years, standard deviation [SD] = 7.2 years) who were 9.2 [5.2] years post-treatment. Approximately one-third (n = 219, 35.0%) of survivors were prescribed at least one chronic medication. Frequently prescribed medication classes include systemic antihistamines (26.5%), sex hormones (19.2%), and thyroid replacement therapy (16.0%). Overall prevalence of polypharmacy was 5.3% (n = 33). A higher rate of polypharmacy was found in survivors of CNS tumors (13.6%) than in survivors of hematological malignancies (4.3%) and other solid tumors (5.3%) (P = .0051). Higher medication burden was also observed in survivors who had undergone cranial radiation (RR = 6.31; 95% CI = 2.75–14.49) or hematopoietic stem-cell transplantation (HSCT) (RR = 3.53; 95% CI = 1.59–7.83).ConclusionAlthough polypharmacy was observed in a minority of included survivors of childhood cancer, chronic medication use was common. Special attention should be paid to survivors of CNS tumors and survivors who have undergone HSCT or cranial radiation. These individuals should be monitored closely for drug–drug interactions and adverse health outcomes that may result from multiple chronic medications, particularly during hospitalization in an acute care setting.

scholarly journals Health problems in survivors of childhood cancer: the need for international collaboration in long-term follow-up care

2013 ◽  
Vol 9 (11) ◽  
pp. 1667-1670 ◽  
Author(s):  
Renée L Mulder ◽  
Melissa M Hudson ◽  
Roderick Skinner ◽  
Leontien CM Kremer
Keyword(s):  
Childhood Cancer ◽  
International Collaboration ◽  
Health Problems ◽  
Follow Up Care ◽  
Long Term Follow Up ◽  
Survivors Of Childhood Cancer

A review of long-term follow-up for survivors of childhood cancer

2007 ◽  
Vol 43 (12) ◽  
pp. 1781-1790 ◽  
Author(s):  
Helen Aslett ◽  
Gill Levitt ◽  
Alison Richardson ◽  
Faith Gibson
Keyword(s):  
Childhood Cancer ◽  
Long Term Follow Up ◽  
Survivors Of Childhood Cancer
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