Hepatitis B virus pre-S2
 mutant large surface protein inhibits DNA double-strand break repair and leads to genome instability in hepatocarcinogenesis

Yi-Hsuan Hsieh; Yu-Ying Chang; Ih-Jen Su; Chia-Jui Yen; Yi-Ru Liu; Ren-Jei Liu; Wen-Chuan Hsieh; Hung-Wen Tsai; Lily Hui-Ching Wang; Wenya Huang

doi:10.1002/path.4531

Hepatitis B virus pre-S2 mutant large surface protein inhibits DNA double-strand break repair and leads to genome instability in hepatocarcinogenesis

The Journal of Pathology ◽

10.1002/path.4531 ◽

2015 ◽

Vol 236 (3) ◽

pp. 337-347 ◽

Cited By ~ 24

Author(s):

Yi-Hsuan Hsieh ◽

Yu-Ying Chang ◽

Ih-Jen Su ◽

Chia-Jui Yen ◽

Yi-Ru Liu ◽

...

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Genome Instability ◽

Surface Protein ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

B Virus ◽

Break Repair

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Elevated double-strand break repair protein RAD50 predicts poor prognosis in hepatitis B virus-related hepatocellular carcinoma: A study based on Chinese high-risk cohorts

Journal of Cancer ◽

10.7150/jca.46703 ◽

2020 ◽

Vol 11 (20) ◽

pp. 5941-5952

Author(s):

Wangrui Liu ◽

Wenhao Xu ◽

Yuyan Chen ◽

Liugen Gu ◽

Xiaolei Sun ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Hepatitis B Virus ◽

High Risk ◽

Hepatitis B ◽

Poor Prognosis ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Repair Protein ◽

B Virus

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Faculty Opinions recommendation of Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017512.204275 ◽

2004 ◽

Author(s):

Michael B Yaffe

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Break Repair

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Faculty Opinions recommendation of The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10202956.12871066 ◽

2011 ◽

Author(s):

Claire Wyman

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Break Repair

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Faculty Opinions recommendation of The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10202956.11019054 ◽

2011 ◽

Author(s):

Hao Wu ◽

Jixi Li

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Break Repair

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Faculty Opinions recommendation of Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1089242.542442 ◽

2007 ◽

Author(s):

Stephen Jackson

Keyword(s):

Chromatin Structure ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Structure Modulation ◽

Break Repair

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Faculty Opinions recommendation of Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1104438.560671 ◽

2008 ◽

Author(s):

Carlos Telleria

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Nonhomologous End Joining ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair

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Faculty Opinions recommendation of A role for small RNAs in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14263986.790202827 ◽

2012 ◽

Author(s):

Traci Hall

Keyword(s):

Small Rnas ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Break Repair

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Faculty Opinions recommendation of A role for small RNAs in DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14263986.15779121 ◽

2012 ◽

Author(s):

Luc DesGroseillers

Keyword(s):

Small Rnas ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Break Repair

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Faculty Opinions recommendation of Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717988297.793472681 ◽

2013 ◽

Author(s):

Yamini Dalal

Keyword(s):

Chromatin Remodeling ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Break Repair

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Faculty Opinions recommendation of Mitosis inhibits DNA double-strand break repair to guard against telomere fusions.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718319148.793496827 ◽

2014 ◽

Author(s):

Fabrizio d'Adda di Fagagna ◽

Francesca Rossiello

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

Dna Double Strand Break ◽

Break Repair

Download Full-text