Clear-cell adenofibroma can be a clonal precursor for clear-cell adenocarcinoma of the ovary: a possible alternative ovarian clear-cell carcinogenic pathway

2008 ◽  
pp. n/a-n/a ◽  
Author(s):  
S Yamamoto ◽  
H Tsuda ◽  
M Takano ◽  
K Hase ◽  
S Tamai ◽  
...  
Keyword(s):  
Clear Cell ◽  
Clear Cell Adenocarcinoma ◽  
Adenocarcinoma Of The Ovary ◽  
Clear Cell Adenofibroma

Ovarian Clear Cell Adenofibroma of Low Malignant Potential Developing Into Clear Cell Adenocarcinoma

2018 ◽  
Vol 26 (6) ◽  
pp. 578-580
Author(s):  
Zhiwei Yin ◽  
Stephen Peters ◽  
Ravi Chokshi ◽  
Debra Heller
Keyword(s):  
Clear Cell ◽  
Malignant Potential ◽  
Clear Cell Adenocarcinoma ◽  
Precursor Lesion ◽  
Borderline Tumors ◽  
Low Malignant Potential ◽  
Adenocarcinoma Of The Ovary ◽  
Clear Cell Adenofibroma

Ovarian clear cell adenofibroma is uncommon, and borderline clear cell adenofibroma (low malignant potential) is extremely rare. Borderline clear cell adenofibromas may represent the precursor lesion of clear cell adenocarcinoma of the ovary, but this has not been established. We present a case of a woman in her mid-50s with a clear cell adenofibroma ranging from benign to borderline to frankly invasive. While some clear cell adenocarcinomas are thought to arise from endometriosis, this range of findings supports the theory that some ovarian clear cell adenocarcinomas originate from borderline tumors.

Establishment of a New Cell Line (TAYA) of Clear Cell Adenocarcinoma of the Ovary and Its Radiosensitivity

Oncology ◽  
2002 ◽  
Vol 62 (2) ◽  
pp. 180-184 ◽  
Author(s):  
Yasushi Saga ◽  
Mitsuaki Suzuki ◽  
Shizuo Machida ◽  
Michitaka Ohwada ◽  
Ikuo Sato
Keyword(s):  
Cell Line ◽  
Clear Cell ◽  
Clear Cell Adenocarcinoma ◽  
New Cell Line ◽  
Adenocarcinoma Of The Ovary

Low Expression of S100P Is Associated With Poor Prognosis in Patients With Clear Cell Adenocarcinoma of the Ovary

2015 ◽  
Vol 25 (9) ◽  
pp. 1582-1586 ◽  
Author(s):  
Yasushi Umezaki ◽  
Masahiro Ito ◽  
Masahiro Nakashima ◽  
Yumi Mihara ◽  
Hirokazu Kurohama ◽  
...  
Keyword(s):  
Cancer Progression ◽  
Poor Prognosis ◽  
Clear Cell ◽  
Acquired Resistance ◽  
Rank Test ◽  
Clear Cell Adenocarcinoma ◽  
Positive Staining ◽  
Ovarian Clear Cell Adenocarcinoma ◽  
Kaplan Meier ◽  
Adenocarcinoma Of The Ovary

ObjectiveThe S100P protein stimulates cell proliferation and survival, thereby contributing to cancer progression. The purposes of this study were to evaluate S100P expression in ovarian clear cell adenocarcinoma and to determine whether S100P expression was correlated with the clinicopathological features or prognoses of patients with clear cell adenocarcinoma.MethodsWe examined S100P expression in 30 ovarian clear cell adenocarcinoma specimens using immunohistochemistry analysis. The Kaplan-Meier method was used for analysis of overall survival, and comparisons were made based on the log-rank test.ResultsNegative staining for nuclear S100P was associated with a poor prognosis as compared with that of positive staining for nuclear S100P in specimens from patients with clear cell adenocarcinoma.ConclusionsThese data suggested that S100P may serve as an independent prognostic factor and marker for acquired resistance to chemotherapeutic drugs in clear cell adenocarcinoma.

scholarly journals Effect of ARID1A/BAF250a expression on carcinogenesis and clinicopathological factors in pure-type clear cell adenocarcinoma of the ovary

2016 ◽  
Vol 5 (4) ◽  
pp. 395-401 ◽  
Author(s):  
Masafumi Kato ◽  
Masashi Takano ◽  
Morikazu Miyamoto ◽  
Naoki Sasaki ◽  
Tomoko Goto ◽  
...  
Keyword(s):  
Clear Cell ◽  
Clear Cell Adenocarcinoma ◽  
Clinicopathological Factors ◽  
Pure Type ◽  
Adenocarcinoma Of The Ovary
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