Development of papillary renal cell tumours is associated with loss of Y-chromosome-specific DNA sequences

1994 ◽  
Vol 173 (1) ◽  
pp. 39-44 ◽  
Author(s):  
Gyula Kovacs ◽  
Kalman Tory ◽  
Angela Kovacs
Keyword(s):  
Y Chromosome ◽  
Dna Sequences ◽  
Renal Cell ◽  
Renal Cell Tumours

scholarly journals Duplication and overexpression of the mutant allele of the MET proto-oncogene in multiple hereditary papillary renal cell tumours

Oncogene ◽  
1998 ◽  
Vol 17 (6) ◽  
pp. 733-739 ◽  
Author(s):  
Joachim Fischer ◽  
Gabriele Palmedo ◽  
Rolf von Knobloch ◽  
Peter Bugert ◽  
Thomas Prayer-Galetti ◽  
...  
Keyword(s):  
Renal Cell ◽  
Mutant Allele ◽  
Renal Cell Tumours

Identification of sex in hop (Humulus lupulus) using molecular markers

Genome ◽  
1997 ◽  
Vol 40 (3) ◽  
pp. 357-361 ◽  
Author(s):  
Andreas Polley ◽  
Martin W. Ganal ◽  
Elisabeth Seigner
Keyword(s):  
Molecular Markers ◽  
Y Chromosome ◽  
Dna Sequences ◽  
Sex Chromosome ◽  
Rapid Identification ◽  
Humulus Lupulus ◽  
Specific Product ◽  
Male And Female ◽  
Cultivated Plant ◽  
Male Specific

The rapid identification of sex in the dioecious hop (Humulus lupulus) is important for the breeding of this cultivated plant because only unfertilized flowers of the female plants are used as an ingredient in the production of beer. It is thought that a sex-chromosome mechanism controls the development of male or female plants. We have compared pools of male and female plants derived from a hop cross to identify molecular markers associated with the Y or male-specific chromosome. Of 900 functional RAPD primers, 32 revealed fragments specific for male plants that were absent in female plants of this cross. Subsequently, the 32 positive primers were tested on unrelated male and female plants. Three of these 32 primers were specific for the Y chromosome in all lines. The Y-specific product derived from one of these primers (OPJ9) was of low copy in hybridization experiments and predominantly present in male plants. Primers developed from the DNA sequence of this product provide a marker for rapid sex identification in crosses of hop by means of PCR.Key words: chromosomes, RAPD, sex-specific DNA sequences, plant breeding, Y chromosome.

Nuclear maspin detection in renal cell tumours: possible diagnostic role and correlation with p53 status

2006 ◽  
Vol 49 (3) ◽  
pp. 274-282 ◽  
Author(s):  
S Blandamura ◽  
L Giacomelli ◽  
G Leo ◽  
P Segato ◽  
V Ninfo
Keyword(s):  
Renal Cell ◽  
Diagnostic Role ◽  
P53 Status ◽  
Renal Cell Tumours

Molecular Cytogenetic Analysis of Karyotype and Y Chromosome Conservation in Species of the Genus Talpa (Insectivora)

2020 ◽  
Vol 160 (5) ◽  
pp. 264-271
Author(s):  
Juana Gutierrez ◽  
Gael Aleix-Mata ◽  
Juan A. Marchal ◽  
María Arroyo ◽  
Riccardo Castiglia ◽  
...  
Keyword(s):  
Sequence Analysis ◽  
Y Chromosome ◽  
Repetitive Dna ◽  
Dna Sequences ◽  
Chromosome Painting ◽  
Chromosomal Mapping ◽  
Repeated Dna ◽  
Molecular Cytogenetic ◽  
Y Chromosomes ◽  
Cytogenetic Analyses

The Talpidae family has a highly stable karyotype. Most of the chromosome studies in this mammal group, however, employed classical cytogenetic techniques. Molecular cytogenetic analyses are still scarce and, for example, no repeated DNA sequences have been described to date. In this work, we used sequence analysis, chromosomal mapping of a LINE1 retroelement sequence, as well as chromosome painting with a whole Y chromosome probe of T. occidentalis to compare the karyotypes of 3 species of the genus Talpa (T. occidentalis, T. romana, and T. aquitania). Our results demonstrate that in Talpa genomes LINE1 sequences are widely distributed on all chromosomes but are enriched in pericentromeric C-band-positive regions. In addition, these LINE1 accumulate on the Y chromosomes of the 3 Talpa species regardless of their euchromatic or heterochromatic condition. Chromosome painting shows that the Y chromosomes in these 3 species are highly conserved. Interestingly, they share sequences with heterochromatic blocks on chromosome pairs 14 and 16 and, to a lesser degree, with the pericentromeric regions of other autosomes. Together, our analyses demonstrate that the repetitive DNA content of chromosomes from Talpa species is highly conserved.

Mapping the human Y chromosome

1988 ◽  
Vol 322 (1208) ◽  
pp. 125-131 ◽  
Keyword(s):  
Y Chromosome ◽  
Dna Sequences ◽  
Physical Map ◽  
Sex Reversal ◽  
Chromosomal Anomalies ◽  
Deletion Mapping ◽  
Molecular Analyses ◽  
Large Size ◽  
Definition Of ◽  
Human Y Chromosome

This paper reviews past and present trends in mapping the human Y chromosome. So far, mapping has essentially used a combination of cytogenetic and molecular analyses of Y-chromosomal anomalies and sex reversal syndromes. This deletion mapping culminated recently in the isolation of the putative sex-determining locus TDF . With the availability of new separation and cloning techniques suited for large size fragments (over 100 kilobases), the next step will consist rather in the establishment of a physical map of fragments of known physical sizes. This may allow the definition of several variants of the human Y chromosome differing by the order or location of DNA sequences along the molecule.

Pathological classification of renal cell tumours

2020 ◽  
Author(s):  
Lukasz Adamczyk ◽  
Paidamwoyo Gwiti ◽  
Jon Oxley
Keyword(s):  
Renal Cell ◽  
Pathological Classification ◽  
Renal Cell Tumours

Breakage of the human Y-chromosome short arm between two blocks of tandemly repeated DNA sequences

Genomics ◽  
1989 ◽  
Vol 5 (1) ◽  
pp. 153-156 ◽  
Author(s):  
Ulrich Müller ◽  
Marc Lalande ◽  
Timothy A. Donlon ◽  
Michael W. Heartlein
Keyword(s):  
Y Chromosome ◽  
Dna Sequences ◽  
Repeated Dna ◽  
Repeated Dna Sequences ◽  
Human Y Chromosome ◽  
Tandemly Repeated Dna

Analysis ofras DNA sequences in rat renal cell carcinoma

1991 ◽  
Vol 4 (5) ◽  
pp. 350-353 ◽  
Author(s):  
Leslie Recio ◽  
Steven C. Lane ◽  
Julie Ginsler ◽  
Cheryl Walker
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Dna Sequences ◽  
Renal Cell
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