The utility of Ki67 immunostaining, nuclear organizer region counting, and morphology in the assessment of follicular lymphomas

1989 ◽  
Vol 158 (3) ◽  
pp. 189-193 ◽  
Author(s):  
M. L. Cibull ◽  
A. Heryet ◽  
K. C. Gatter ◽  
D. Y. Mason
Keyword(s):  
Organizer Region ◽  
Follicular Lymphomas ◽  
Nuclear Organizer Region

scholarly journals Assessment of proliferative index in different grades of breast cancers using AgNOR (Agyrophilic Nuclear Organizer Region) expression

2018 ◽  
Vol 7 (4) ◽  
pp. 587-592
Author(s):  
Williams Kweku Darkwah ◽  
Gideon Aidoo ◽  
Yanhui Ao ◽  
Kwabena Owusu Danquah ◽  
Ernest Adjei ◽  
...  
Keyword(s):  
Organizer Region ◽  
Breast Cancers ◽  
Proliferative Index ◽  
Nuclear Organizer Region

Nuclear Organizer Region in Establishing Postmortem Interval

2016 ◽  
Vol 16 (1) ◽  
pp. 150
Author(s):  
Charan BK Gowda ◽  
CV Mohan ◽  
S Hemavathi
Keyword(s):  
Organizer Region ◽  
Postmortem Interval ◽  
Nuclear Organizer Region

scholarly journals Proliferative activity of various grades and types of breast carcinoma using AgNOR (Argyrophilic Nuclear Organizer Region) expression and its prognostic significance

All Life ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 375-391
Author(s):  
Williams Kweku Darkwah ◽  
Gideon Aidoo ◽  
Dickson Akoto ◽  
Kadri Alhassan ◽  
Buanya Beryl Adormaa ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Proliferative Activity ◽  
Organizer Region ◽  
Prognostic Significance ◽  
Nuclear Organizer Region

scholarly journals Argyrophilic nuclear organizer region and p73 expression in head and neck squamous cell carcinomas: Teammates or adversaries?

2016 ◽  
Vol 20 (3) ◽  
pp. 427
Author(s):  
SunilPazhayanur Venkateswaran ◽  
LevianaErcylina Nathan ◽  
VimiSunil Mutalik ◽  
NoorHasni Shamsuddin
Keyword(s):  
Head And Neck ◽  
Squamous Cell ◽  
Organizer Region ◽  
Squamous Cell Carcinomas ◽  
Nuclear Organizer Region

Argyrophilic Nuclear Organizer Region Counts and Ki-67 Scores in Human Renal Cell Carcinoma

1991 ◽  
Vol 187 (4) ◽  
pp. 482-486 ◽  
Author(s):  
A. Pich ◽  
G. Valente ◽  
L. Azzoni ◽  
A. Stramignoni ◽  
E. Margaria ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Organizer Region ◽  
Ki 67 ◽  
Human Renal Cell Carcinoma ◽  
Nuclear Organizer Region

scholarly journals Comparative FISH analysis of Senna tora tandem repeats revealed insights into the chromosome dynamics in Senna

2021 ◽  
Vol 43 (3) ◽  
pp. 237-249 ◽  
Author(s):  
Thanh Dat Ta ◽  
Nomar Espinosa Waminal ◽  
Thi Hong Nguyen ◽  
Remnyl Joyce Pellerin ◽  
Hyun Hee Kim
Keyword(s):  
Tandem Repeats ◽  
Chromosomal Rearrangements ◽  
Organizer Region ◽  
Nucleolar Organizer Region ◽  
Nucleolar Organizer ◽  
Pericentromeric Region ◽  
Its2 Sequence ◽  
Fish Analysis ◽  
Chromosomal Distribution ◽  
Chromosome Dynamics

Abstract Background DNA tandem repeats (TRs) are often abundant and occupy discrete regions in eukaryotic genomes. These TRs often cause or generate chromosomal rearrangements, which, in turn, drive chromosome evolution and speciation. Tracing the chromosomal distribution of TRs could therefore provide insights into the chromosome dynamics and speciation among closely related taxa. The basic chromosome number in the genus Senna is 2n = 28, but dysploid species like Senna tora have also been observed. Objective To understand the dynamics of these TRs and their impact on S. tora dysploidization. Methods We performed a comparative fluorescence in situ hybridization (FISH) analysis among nine closely related Senna species and compared the chromosomal distribution of these repeats from a cytotaxonomic perspective by using the ITS1-5.8S-ITS2 sequence to infer phylogenetic relationships. Results Of the nine S. tora TRs, two did not show any FISH signal whereas seven TRs showed similar and contrasting patterns to other Senna species. StoTR01_86, which was localized in the pericentromeric regions in all S. tora, but not at the nucleolar organizer region (NOR) site, was colocalized at the NOR site in all species except in S. siamea. StoTR02_7_tel was mostly localized at chromosome termini, but some species had an interstitial telomeric repeat in a few chromosomes. StoTR05_180 was distributed in the subtelomeric region in most species and was highly amplified in the pericentromeric region in some species. StoTR06_159 was either absent or colocalized in the NOR site in some species, and StoIGS_463, which was localized at the NOR site in S. tora, was either absent or localized at the subtelomeric or pericentromeric regions in other species. Conclusions These data suggest that TRs play important roles in S. tora dysploidy and suggest the involvement of 45S rDNA intergenic spacers in “carrying” repeats during genome reshuffling.

scholarly journals The genomic structure of a human chromosome 22 nucleolar organizer region determined by TAR cloning

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jung-Hyun Kim ◽  
Vladimir N. Noskov ◽  
Aleksey Y. Ogurtsov ◽  
Ramaiah Nagaraja ◽  
Nikolai Petrov ◽  
...  
Keyword(s):  
Genomic Structure ◽  
Organizer Region ◽  
Nucleolar Organizer Region ◽  
Nucleolar Organizer ◽  
Chromosome 21 ◽  
Reference Sequence ◽  
Chromosome 22 ◽  
Rdna Variation ◽  
High Level ◽  
Tar Cloning

AbstractThe rDNA clusters and flanking sequences on human chromosomes 13, 14, 15, 21 and 22 represent large gaps in the current genomic assembly. The organization and the degree of divergence of the human rDNA units within an individual nucleolar organizer region (NOR) are only partially known. To address this lacuna, we previously applied transformation-associated recombination (TAR) cloning to isolate individual rDNA units from chromosome 21. That approach revealed an unexpectedly high level of heterogeneity in human rDNA, raising the possibility of corresponding variations in ribosome dynamics. We have now applied the same strategy to analyze an entire rDNA array end-to-end from a copy of chromosome 22. Sequencing of TAR isolates provided the entire NOR sequence, including proximal and distal junctions that may be involved in nucleolar function. Comparison of the newly sequenced rDNAs to reference sequence for chromosomes 22 and 21 revealed variants that are shared in human rDNA in individuals from different ethnic groups, many of them at high frequency. Analysis infers comparable intra- and inter-individual divergence of rDNA units on the same and different chromosomes, supporting the concerted evolution of rDNA units. The results provide a route to investigate further the role of rDNA variation in nucleolar formation and in the empirical associations of nucleoli with pathology.

Leukemic phase of follicular lymphomas: an atypical presentation

2011 ◽  
Vol 52 (8) ◽  
pp. 1504-1508 ◽  
Author(s):  
Chadi Al-nawakil ◽  
Olivier Kosmider ◽  
Marc-Henri Stern ◽  
Elodie Manié ◽  
ValéRIE Bardet ◽  
...  
Keyword(s):  
Atypical Presentation ◽  
Leukemic Phase ◽  
Follicular Lymphomas
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