The response of small blood vessels in rat skin and skeletal muscle to repeated application of histamine: A chemical, topographical and electron microscopic study

1985 ◽  
Vol 146 (4) ◽  
pp. 291-299 ◽  
Author(s):  
Gayle M. Jones ◽  
John V. Hurley
Keyword(s):  
Skeletal Muscle ◽  
Blood Vessels ◽  
Microscopic Study ◽  
Electron Microscopic Study ◽  
Repeated Application ◽  
Rat Skin ◽  
Electron Microscopic

scholarly journals THE ULTRASTRUCTURE OF THE Z DISC IN SKELETAL MUSCLE

1962 ◽  
Vol 13 (2) ◽  
pp. 323-335 ◽  
Author(s):  
G. G. Knappeis ◽  
F. Carlsen
Keyword(s):  
Skeletal Muscle ◽  
Microscopic Study ◽  
Electron Microscopic Study ◽  
Cross Sections ◽  
Electron Microscopic ◽  
Structural Arrangement ◽  
Special Regard ◽  
Pass Through

This electron microscopic study deals with the structure of the Z disc of frog's skeletal muscle, with special regard to the I filaments—whether they pass through the Z disc or terminate at it. In most longitudinal sections the I filaments terminate as rod-like projections on either side of the Z disc, one I filament on one side lying between two I filaments on the opposite side. This indicates that the I filaments are not continuous through the Z disc. The rod-like projections are often seen to consist of filaments (denoted as Z filaments) which meet at an angle. In cross-sections through the Z region the I filaments and Z filaments form tetragonal patterns. The I filaments are situated in the corners of the squares; the oblique Z filaments form the sides of squares. The tetragonal pattern formed by the Z filaments is rotated 45 degrees with respect to the tetragons formed by the I filaments on both sides of Z. This structural arrangement is interpreted to indicate that each I filament on one side of the Z disc faces the center of the space between four I filaments on the opposite side of Z and that the interconnection is formed by four Z filaments.

A HISTOCHEMICAL AND ELECTRON MICROSCOPIC STUDY OF SKELETAL MUSCLE IN A CASE OF POMPE'S DISEASE (GLYCOGENOSIS II)

PEDIATRICS ◽  
1966 ◽  
Vol 37 (2) ◽  
pp. 249-259
Author(s):  
Robert Darrell Cardiff
Keyword(s):  
Skeletal Muscle ◽  
Microscopic Study ◽  
Electron Microscopic Study ◽  
Striated Muscle ◽  
Electron Microscopic ◽  
Pompe’S Disease ◽  
Pompe's Disease ◽  
Microscopic Studies ◽  
Alpha Glucosidase ◽  
Glycogenosis Ii

1. A case of Pompe's disease (glycogenosis II) without biochemically or histochemically demonstrable alpha-glucosidase activity is described. 2. Histochemical studies of skeletal muscle suggested that the glycogen is frequently stored as an acid mucopolysaccharide. 3. Electron microscopic studies revealed that the major glycogen deposits in most tissue were within membrane-limited sacs. Striated muscle was an exception because major deposits were frequently extrasaccular. 4. The findings in this case are discussed in relation to current concepts of Pompe's disease. In view of the extrasaccular glycogen deposits in skeletal muscle, it is suggested that an extralysosomal factor plays a significant role in the pathogenesis of Pompe's disease.

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