scholarly journals Monitoring the efficacy of omega-3 supplementation on liver steatosis and carotid intima-media thickness: a pilot study

2017 ◽  
Vol 3 (2) ◽  
pp. 201-211 ◽  
Author(s):  
M. -C. Lacasse ◽  
A. Tang ◽  
J. Dubois ◽  
F. Alvarez ◽  
S. Spahis ◽  
...  
Keyword(s):  
Pilot Study ◽  
Liver Steatosis ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Omega 3 ◽  
Media Thickness

Abstract P301: Association of Toenail Cadmium Levels with Measures of Sub-Clinical Atherosclerosis: The Coronary Artery Risk Development in Young Adults (CARDIA) Trace Element Study

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Pengcheng Xun ◽  
Kiang Liu ◽  
Steve Morris ◽  
Martha Daviglus ◽  
Catherine Loria ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Coronary Artery ◽  
Body Mass ◽  
Smoking Status ◽  
Experimental Studies ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Omega 3 ◽  
Media Thickness ◽  
Cd Exposure

Background: Experimental studies have suggested that cadmium (Cd) exposure is a potential risk factor for early atherosclerosis and cardiovascular diseases as it can disrupt integrity of the endothelial cell layer. However, longitudinal data in humans relating Cd levels to sub-clinical atherosclerosis are lacking. Methods: 2589 participants from the CARDIA Study, aged 20-32 years in 1987 (baseline) with up to 18 years of follow-up were included in the analyses to examine prospectively the associations of toenail Cd concentrations with carotid intima-media thickness (CIMT) and coronary artery calcium score (CAC score). Toenail clippings were collected in 1987 and Cd was assessed by instrumental neutron-activation analysis. Common (c), bulb (b), and internal (i) CIMTs were measured in 2005 and CAC score in 2000 and 2005. CAC presence (score, >0 Agatston units) and CAC progression (incident CAC in 2005 or increase in CAC score by ≥10 Agatston units) were defined based on CAC score. General linear regression or logistic regression was used as appropriate. Results: Median Cd levels were 0.003, 0.006, 0.012 and 0.039 μ g/g from 1 st - 4 th quartile. We observed a positive linear relation of Cd levels with cCIMT, but not bCIMT and iCIMT ( Table 1 ). Null associations between Cd levels and CAC progression [Q 4 vs . Q 1 : OR=1.11 (95% CI: 0.73, 1.68); P trend =0.14] or presence of CAC [Q 4 vs . Q 1 : OR=1.05 (0.73, 1.53); P trend =0.56] were documented. Conclusions: In this young adult cohort, toenail Cd levels were positively associated with cCIMT, but not bCIMT, iCIMT and CAC score. Further studies are needed to determine whether there is an atherosclerotic mechanism linking Cd exposure to the risk of cardiovascular disease. Table 1 Multivariable-adjusted carotid intima-media thickness (mm) by toenail cadmium levels No. of participants Quartile of toenail cadmium levels P trend Q1 Q2 Q3 Q4 cCIMT 2587 0.781 (0.773-0.790) 0.784 (0.776-0.793) 0.789 (0.781-0.798) 0.791 (0.781-0.798) 0.03 bCIMT 2527 1.010 (0.990-0.1.031) 1.002 (0.982-1.022) 0.981 (0.962-1.001) 1.001 (0.980-1.022) 0.17 iCIMT 2436 0.787 (0.772-0.802) 0.790 (0.776-0.804) 0.784 (0.770-0.798) 0.778 (0.763-0.793) 0.86 Data are geometric means (95%CIs) adjusted for age, gender, race, study center, body mass index, physical activity, education, smoking status, alcohol consumption, systolic blood pressure, LDL/HDL, HOMA, body mass index, long-chain omega-3 polyunsaturated fatty acids intake with toenail zinc, chromium, lead and mass weight. cCIMT : common carotid intima-media thickness; bCIMT : bulb carotid intima-media thickness; iCIMT : internal carotid intima-media thickness.

Increased carotid intima media thickness is associated with prolactin levels in subjects with untreated prolactinoma: a pilot study

Pituitary ◽  
2013 ◽  
Vol 17 (3) ◽  
pp. 232-239 ◽  
Author(s):  
Xiao-Bing Jiang ◽  
Cui-Ling Li ◽  
Dong-Sheng He ◽  
Zhi-Gang Mao ◽  
Dong-Hong Liu ◽  
...  
Keyword(s):  
Pilot Study ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness

scholarly journals Liraglutide decreases carotid intima-media thickness in patients with type 2 diabetes: 8-month prospective pilot study

2014 ◽  
Vol 13 (1) ◽  
pp. 49 ◽  
Author(s):  
Manfredi Rizzo ◽  
Manisha Chandalia ◽  
Angelo Patti ◽  
Vittoria Di Bartolo ◽  
Ali A Rizvi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Pilot Study ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Prospective Pilot Study ◽  
Media Thickness

scholarly journals Carotid intima media thickness in patients with sporadic idiopathic hypoparathyroidism: a pilot study

2012 ◽  
Vol 59 (7) ◽  
pp. 555-559 ◽  
Author(s):  
Yashdeep Gupta ◽  
Sanjay Kumar Bhadada ◽  
Viral N Shah ◽  
Vimal Upreti ◽  
Anil Bhansali ◽  
...  
Keyword(s):  
Pilot Study ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness
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