scholarly journals Efficient Synthesis of the N- (buta-2,3-dienyl)carboxamide of Isopimaric Acid and the Potential of This Compound towards Heterocyclic Derivatives of Diterpenoids

ChemistryOpen ◽  
2018 ◽  
Vol 7 (11) ◽  
pp. 890-901 ◽  
Author(s):  
Marya A. Gromova ◽  
Yurii V. Kharitonov ◽  
Irina Yu. Bagryanskaya ◽  
Elvira E. Shults
Keyword(s):  
Efficient Synthesis ◽  
Isopimaric Acid ◽  
Heterocyclic Derivatives ◽  
Derivatives Of

Heterocyclic derivatives of purines. 5. Nucleophilic substitution in series of imidazo[1,2-f]purine derivatives

1984 ◽  
Vol 20 (3) ◽  
pp. 330-334
Author(s):  
S. N. Garmash ◽  
B. A. Priimenko ◽  
N. A. Klyuev ◽  
N. I. Romanenko ◽  
A. K. Sheinkman
Keyword(s):  
Nucleophilic Substitution ◽  
Purine Derivatives ◽  
Heterocyclic Derivatives ◽  
In Series ◽  
Derivatives Of

Angular condensed heterocyclic derivatives of ?-naphthol

1970 ◽  
Vol 6 (4) ◽  
pp. 513-515
Author(s):  
T. Kh. Gladysheva ◽  
M. V. Gorelik
Keyword(s):  
Heterocyclic Derivatives ◽  
Derivatives Of

scholarly journals Synthesis of bis-Heterocyclic Derivatives of Thiohydantoin

INEOS OPEN ◽  
2021 ◽  
Vol 4 ◽  
Author(s):  
O. N. Gorunova ◽  
◽  
N. A. Bystrova ◽  
K. A. Kochetkov ◽  
◽  
...  
Keyword(s):  
Structural Modification ◽  
Suggested Approach ◽  
Heterocyclic Derivatives ◽  
Derivatives Of

The possibility of structural modification of thiohydantoin derivatives via amidoalkylation under the action of a range of cyclic hemiamidals is demonstrated. The suggested approach provides, in particular, unsymmetrical nitrogen-containing bis-heterocyclic systems with pharmacologically relevant groups that are difficult to obtain by other methods.

scholarly journals Synthesis and Evaluation Antibacterial Activity of Some New Substituted 5-Bromoisatin Containing Five, Six Heterocyclic Ring

2016 ◽  
Vol 13 (2) ◽  
pp. 345-359
Author(s):  
Baghdad Science Journal
Keyword(s):  
Heterocyclic Ring ◽  
Absolute Ethanol ◽  
Synthesis Process ◽  
Triazole Derivatives ◽  
Amide Derivatives ◽  
Heterocyclic Derivatives ◽  
Acid Anhydrides ◽  
Specific Reactions ◽  
Derivatives Of ◽  
Product Compound

This research includes the synthesis of some new different heterocyclic derivatives of 5-Bromoisatin. New sulfonylamide, diazine, oxazole, thiazole and 1,2,3-triazole derivatives of 5-Bromoisatin have been synthesized. The synthesis process started by the reaction of 5-Bromoisatin with different reagents to obtain schiff bases of 5-Bromoisatin intermediate compounds(1, 8, 19) by using glacial acetic acid as a catalyst in three routes. The first route, 5-Bromoisatin reacted with p-aminosulfonylchloride to product compound(1), then converted to sulfonyl amide derivatives(2-7) by the reaction of compound(1) with different substituted primary aromatic amine in absolute ethanol. The second route includes the reaction of 5-Bromoisatin reacted with ethyl glycinate to give 5-bromo-3-(Ethyl imino acetate)-2-oxo indole(8), which undergo react with hydrazine hydrate 80% to obtain hydrazine derivatives(9) that react with different acid anhydrides to obtain diazine derivatives(10-14). Also compound(8) reacts with urea and thiourea to give compounds(15,16) which undergo cyclization with p-bromophenacylbromide in absolute ethanol as a solvent to obtain oxazole (17) and thiazole (18), respectively. The third route included the reaction of 5-Bromoisatin with p-phenylenediamine in ethanol to obtain compound(19) which is converted to new substitutes 1,2,3-triazole derivatives(22,23) by diazotation of compound(19) and treating the resulted salt(20) with sodium azid, then acetylaceton or ethylacetoacetate, respectively. Newly synthesized compounds were identified by spectral methods. (FTIR, 1H-NMR, 13C-NMR) and measurements of some of its physical properties and also some specific reactions. Furthermore the effects of the synthesized compounds were studied on some strains of bacteria.

scholarly journals The reactivity of aromatic and heterocyclic derivatives of hydrazine. Vіі. The acid-base properties of substituted 5,7-dichloro-9-hydrazine acridine

2016 ◽  
Vol 0 (1(85)) ◽  
pp. 12-14
Author(s):  
A. O. Deviatkina ◽  
O. M. Svechnikova ◽  
S. V. Kolisnyk ◽  
N. P. Kobzar ◽  
A. F. Vinnyk
Keyword(s):  
Acid Base ◽  
Heterocyclic Derivatives ◽  
Derivatives Of ◽  
Base Properties

Synthesis, characterization and antimicrobial study via new heterocyclic derivatives of trimethoprim

2018 ◽  
Vol 33 (9) ◽  
pp. 1277-1283 ◽  
Author(s):  
Ayad M. R. Raauf ◽  
Rafah F. Al-Smaism ◽  
Khalida A. Thejeel ◽  
Hala Ayad M. Rasheed
Keyword(s):  
Antimicrobial Study ◽  
Heterocyclic Derivatives ◽  
Derivatives Of
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