scholarly journals Increased Risk for Ipsilateral Breast Tumor Recurrence in Invasive Lobular Carcinoma after Accelerated Partial Breast Irradiation Brachytherapy

2021 ◽  
Author(s):  
Matthew N. Mills ◽  
Nicholas W. Russo ◽  
Matthew Fahey ◽  
Ronica H. Nanda ◽  
Sunny Raiker ◽  
...  
Keyword(s):  
Invasive Lobular Carcinoma ◽  
Breast Tumor ◽  
Tumor Recurrence ◽  
Lobular Carcinoma ◽  
Ipsilateral Breast Tumor Recurrence ◽  
Accelerated Partial Breast Irradiation ◽  
Partial Breast Irradiation ◽  
Breast Irradiation ◽  
Ipsilateral Breast ◽  
Increased Risk

Outcome after ipsilateral breast tumor recurrence in patients who receive accelerated partial breast irradiation

Cancer ◽  
2012 ◽  
Vol 118 (17) ◽  
pp. 4126-4131 ◽  
Author(s):  
Chirag Shah ◽  
Frank Vicini ◽  
Martin Keisch ◽  
Henry Kuerer ◽  
Peter Beitsch ◽  
...  
Keyword(s):  
Breast Tumor ◽  
Tumor Recurrence ◽  
Ipsilateral Breast Tumor Recurrence ◽  
Accelerated Partial Breast Irradiation ◽  
Partial Breast Irradiation ◽  
Breast Irradiation ◽  
Ipsilateral Breast

Outcome after Mastectomy for Ipsilateral Breast Tumor Recurrence after Breast Conserving Surgery

2010 ◽  
Vol 76 (8) ◽  
pp. 829-834 ◽  
Author(s):  
H. Randall Beard ◽  
Emily F. Cantrell ◽  
Gregory B. Russell ◽  
Marissa Howard-Mcnatt ◽  
Perry Shen ◽  
...  
Keyword(s):  
Breast Tumor ◽  
Tumor Recurrence ◽  
Ductal Carcinoma ◽  
Ipsilateral Breast Tumor Recurrence ◽  
Breast Conserving Surgery ◽  
Breast Cancer Patients ◽  
Ipsilateral Breast ◽  
Increased Risk ◽  
Group A

Ipsilateral breast tumor recurrence (IBTR) is a risk after breast conserving surgery, and is traditionally treated with mastectomy. Given the limited literature on outcome after mastectomy for IBTR, we evaluated our long-term data for this group. A retrospective review was conducted using a database of 2101 breast cancer patients at a single institution. Fifty-nine patients underwent breast conserving surgery and experienced an IBTR. Exclusion criteria included repeat lumpectomy or metastatic disease before mastectomy. Patients presented with invasive ductal (58%), invasive lobular (7%), other invasive (11%), or ductal carcinoma in situ (24%). Initial tumors were Tis (24%), T1 (42%), T2 (20%), T3 (2%), or not recorded (12%). IBTR lesions were Tis (20%), T1 (46%), T2 (25%), or T3 (9%). Median follow-up after mastectomy was 4.6 years. Thirteen patients (22%) had post-mastectomy recurrence (PMR), which decreased overall survival ( P = 0.002). PMR was more common with larger IBTR tumors ( P = 0.03), specifically IBTR ≥ T2 ( P = 0.003). Eighty-five per cent of PMR occurred within 2 years of mastectomy. Mastectomy for IBTR remains effective treatment for most patients, but the risk of PMR remains. Patients with IBTR tumors >2 cm have an increased risk of PMR. Strict follow-up should be routine, especially during the first 24 months.

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