Mass spectrometry of the triethylsilyl, tri-n-propylsilyl and tri-n-butylsilyl derivatives of some alcohols, steroids and cannabinoids

1977 ◽  
Vol 12 (7) ◽  
pp. 473-474 ◽  
Author(s):  
D. J. Harvey
Keyword(s):  
Mass Spectrometry ◽  
Derivatives Of

Capillary electrophoresis tandem mass spectrometry of bromine-containing charged derivatives of peptides

2007 ◽  
Vol 1159 (1-2) ◽  
pp. 119-124 ◽  
Author(s):  
Györgyi Ferenc ◽  
Petra Pádár ◽  
Tamás Janáky ◽  
Zoltán Szabó ◽  
Gábor K. Tóth ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Capillary Electrophoresis ◽  
Tandem Mass Spectrometry ◽  
Tandem Mass ◽  
Derivatives Of

scholarly journals Rearrangement of spiroderivatives of 1,3-benzo(naphtho)dioxin-4(1)-ones as a new method of synthesis of xanthene bromo derivatives

2021 ◽  
pp. 73-77
Author(s):  
A.V. Kovtun ◽  
◽  
S.A. Varenichenko ◽  
E.V. Zaliznaya ◽  
A.V. Mazepa ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
13C Nmr ◽  
Bromine Atom ◽  
Sodium Perchlorate ◽  
Building Blocks ◽  
Dimethylamino Group ◽  
1H And 13C Nmr ◽  
Molecular Building Blocks ◽  
Derivatives Of ◽  
Fold Excess

We have proposed a method for the synthesis of previously unknown bromo xanthenes using the reagent PBr3/DMF as a rearrangement initiator. Bromo derivatives of xanthenes in the form of organic perchlorates were prepared by reacting the corresponding benzo(naphtho)dioxin-4(1)-ones with a three-fold excess of Vilsmeier-Haack PBr3/DMF reagent at 1100C for 2 hours, followed by the addition of sodium perchlorate. The conditions for the synthesis of formyl derivatives of xanthenes under conditions of acid hydrolysis were selected. The structure of the compounds was confirmed by 1H and 13C NMR spectral data and mass spectrometry. Preliminary studies showed that it is possible to selectively replace the dimethylamino group and the bromine atom with various nucleophiles in bromo derivatives of xanthenes, which opens up wide possibilities for the synthesis of low-molecular building blocks and dyes.

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