Completeness of Intervention Reporting of Clinical Trials Published in Highly Ranked Obesity Journals

Obesity ◽  
2020 ◽  
Author(s):  
Shelby Lynn Rauh ◽  
D’Arcy Turner ◽  
Sam Jellison ◽  
David B. Allison ◽  
Colony Fugate ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Intervention Reporting

Quality of Intervention Reporting in Randomized Clinical Trials Published in Urology Journals

2020 ◽  
Vol 77 (3) ◽  
pp. 296-298 ◽  
Author(s):  
Bradley S. Johnson ◽  
Ian Fladie ◽  
Sam Jellison ◽  
Megan McMurray ◽  
Vikram Narayan ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Intervention Reporting

scholarly journals Consensus on the exercise and dosage variables of an exercise training programme for chronic non-specific neck pain: protocol for an international e-Delphi study

BMJ Open ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. e037656
Author(s):  
Jonathan Price ◽  
Alison Rushton ◽  
Vasileios Tyros ◽  
Nicola R Heneghan
Keyword(s):  
Clinical Trials ◽  
Exercise Training ◽  
Neck Pain ◽  
Delphi Study ◽  
A Priori ◽  
Training Programme ◽  
Ethical Approval ◽  
Strongly Agree ◽  
Training Programmes ◽  
Intervention Reporting

IntroductionClinical guidelines and systematic reviews recommend exercise in the management of chronic non-specific neck pain. Although exercise training programmes that consist of both motor control exercise and exercises for the superficial cervical muscles (segmental exercises) are effective, the exercise variables including dosage vary considerably across trials or are poorly reported. This study aims to gain expert consensus on these exercise variables so that they can be described clearly using intervention reporting checklists to inform clinical practice and future clinical trials.Methods and analysisThis protocol for an international Delphi study is informed by the Guidance on Conducting and REporting DElphi Studies recommendations and published to ensure quality, rigour and transparency. The study will consist of three rounds using anonymous online questionnaires. Expert exercise professionals (physiotherapists, strength and conditioning coaches and so on) and academics in neck pain management will be identified through literature searches, peer referral and social media calls for expression of interest. In round 1, participants will answer open-ended questions informed by intervention and exercise reporting checklists. Responses will be analysed thematically by two independent reviewers. In round 2, participants will rate their level of agreement with statements generated from round 1 and previous clinical trials using a 5-point Likert scale where 1=strongly disagree and 5=strongly agree. In round 3, participants will re-rate their agreement with statements that achieved consensus in round 2. Statements reaching consensus among participants must meet progressively increased a priori criteria at rounds 2 and 3, measured using descriptive statistics: median, IQR and percentage agreement. Inferential statistics will be used to evaluate measures of agreement between participants (Kendall’s coefficient of concordance) and stability between rounds (Wilcoxon rank-sum test). Statements achieving consensus in round 3 will provide expert recommendations of the key exercise and dosage variables in the management of chronic non-specific neck pain.Ethics and disseminationEthical approval was provided by the University of Birmingham Ethics Committee (Ref:ERN_19–1857). Results will be disseminated through peer-reviewed publications and conference presentations.

Evaluation of intervention reporting in published emergency medicine clinical trials

2020 ◽  
Vol 38 (6) ◽  
pp. 1171-1177 ◽  
Author(s):  
Ian A. Fladie ◽  
Drayton Rorah ◽  
Jonathan Pollard ◽  
Samuel Jellison ◽  
Lehana Thabane ◽  
...  
Keyword(s):  
Emergency Medicine ◽  
Clinical Trials ◽  
Intervention Reporting

Localization of Gallium-67 in Peritoneal Cells by Electron Microscopic Autoradiography

1973 ◽  
Vol 31 ◽  
pp. 404-405
Author(s):  
D. C. Swartzendruber ◽  
Norma L. Idoyaga-Vargas
Keyword(s):  
Clinical Trials ◽  
Soft Tissue ◽  
Tumor Tissue ◽  
Soft Tissue Tumors ◽  
Clinical Usefulness ◽  
Electron Microscopic ◽  
Normal Cells ◽  
Electron Microscopic Autoradiography ◽  
Peritoneal Cells ◽  
Gallium 67

The radionuclide gallium-67 (67Ga) localizes preferentially but not specifically in many human and experimental soft-tissue tumors. Because of this localization, 67Ga is used in clinical trials to detect humar. cancers by external scintiscanning methods. However, the fact that 67Ga does not localize specifically in tumors requires for its eventual clinical usefulness a fuller understanding of the mechanisms that control its deposition in both malignant and normal cells. We have previously reported that 67Ga localizes in lysosomal-like bodies, notably, although not exclusively, in macrophages of the spocytaneous AKR thymoma. Further studies on the uptake of 67Ga by macrophages are needed to determine whether there are factors related to malignancy that might alter the localization of 67Ga in these cells and thus provide clues to discovering the mechanism of 67Ga localization in tumor tissue.

Rome I versus Rome II; Overlap in patients enrolled in tegaserod phase III clinical trials for irritable bowel syndrome (IBS)

2001 ◽  
Vol 120 (5) ◽  
pp. A284-A284
Author(s):  
B NAULT ◽  
S SUE ◽  
J HEGGLAND ◽  
S GOHARI ◽  
G LIGOZIO ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Irritable Bowel Syndrome ◽  
Phase Iii ◽  
Phase Iii Clinical Trials ◽  
Irritable Bowel ◽  
Rome I

Clinical trials screening: An opportunity to increase medical care access

2001 ◽  
Vol 120 (5) ◽  
pp. A410-A410
Author(s):  
T KOVASC ◽  
R ALTMAN ◽  
R JUTABHA ◽  
G OHNING
Keyword(s):  
Clinical Trials ◽  
Medical Care ◽  
Care Access
Sign in / Sign up

Export Citation Format

Share Document