scholarly journals Effects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial

Obesity ◽  
2016 ◽  
Vol 24 (4) ◽  
pp. 794-804 ◽  
Author(s):  
Jennifer Daubenmier ◽  
Patricia J. Moran ◽  
Jean Kristeller ◽  
Michael Acree ◽  
Peter Bacchetti ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Weight Loss ◽  
Randomized Clinical Trial ◽  
Weight Loss Intervention

Weight Loss Prior to Pregnancy and Early Gestational Glycemia: Prepare, a Randomized Clinical Trial

2021 ◽  
Author(s):  
Erin S Leblanc ◽  
Ning X Smith ◽  
Kimberly K Vesco ◽  
Teresa A Hillier ◽  
Victor J Stevens
Keyword(s):  
Clinical Trial ◽  
Weight Loss ◽  
Gestational Diabetes ◽  
Usual Care ◽  
Randomized Clinical Trial ◽  
Early Pregnancy ◽  
Diabetes Diagnosis ◽  
Weight Loss Intervention ◽  
Positive Effects ◽  
Pregnancy Weight

Abstract Purpose To determine whether pre-pregnancy weight loss improved the early metabolic environment as measured by early gestational diabetes diagnosis. Methods This was a secondary analysis of a pragmatic randomized clinical trial conducted between May 2015 and October 2019 in an integrated health system that encouraged first trimester gestational diabetes screening for high-risk women, including those with obesity. Women aged 18-40 years with BMI ≥27 kg/m 2 who were planning pregnancy were randomized to a behavioral weight loss intervention or usual care. Clinical care decisions and data collection were blind to condition assignment. We compared rates of diagnosis with gestational diabetes in early pregnancy between the groups using logistic regression. Results Of 326 participants, 168 (89 in the intervention and 79 in usual care) had singleton pregnancies during the study period. At baseline, mean age was 31.3±3.5 years and BMI was 34.8±5.8kg/m 2. Fifty-nine (66%) intervention participants and 57 (72%) usual care participants underwent early screening. Among those, intervention participants were 73% less likely to be diagnosed with gestational diabetes than usual care participants (aOR 0.27 [95%; 0.09, 0.80]). There was no difference in diagnosis of gestational diabetes in later pregnancy (aOR 1.08 [0.41, 2.81]). Main Conclusions Participation in a pre-pregnancy weight loss intervention led to lower rates of gestational diabetes diagnosis in early pregnancy. This suggests positive effects of pre-pregnancy weight loss on the early metabolic environment, a critical factor in offspring metabolic risk.

scholarly journals Fresh Start, a postpartum weight loss intervention for diverse low-income women: design and methods for a randomized clinical trial

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Milagros C. Rosal ◽  
Christina F. Haughton ◽  
Barbara B. Estabrook ◽  
Monica L. Wang ◽  
Germán Chiriboga ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Weight Loss ◽  
Randomized Clinical Trial ◽  
Low Income ◽  
Weight Loss Intervention ◽  
Fresh Start ◽  
Postpartum Weight ◽  
Low Income Women ◽  
Design And Methods

scholarly journals Intensive Weight Loss Intervention and Cancer Risk in Adults with Type 2 Diabetes: Analysis of the Look AHEAD Randomized Clinical Trial

Obesity ◽  
2020 ◽  
Vol 28 (9) ◽  
pp. 1678-1686 ◽  
Author(s):  
◽  
Hsin‐Chieh Yeh ◽  
John P. Bantle ◽  
Maria Cassidy‐Begay ◽  
George Blackburn ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Clinical Trial ◽  
Weight Loss ◽  
Cancer Risk ◽  
Randomized Clinical Trial ◽  
Weight Loss Intervention ◽  
Look Ahead ◽  
The Look

Low-carbohydrate diets lead to greater weight loss and better glucose homeostasis than exercise: a randomized clinical trial

2021 ◽  
Vol 15 (3) ◽  
pp. 460-471
Author(s):  
Lingli Cai ◽  
Jun Yin ◽  
Xiaojing Ma ◽  
Yifei Mo ◽  
Cheng Li ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Weight Loss ◽  
Randomized Clinical Trial ◽  
Glucose Homeostasis ◽  
Low Carbohydrate
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