The impact of plasma brain‐derived neurotrophic factor concentration and weight gain after kidney transplantation

2018 ◽  
Vol 42 (1) ◽  
pp. 82-86
Author(s):  
Chen Lai ◽  
Ansley G. Stanfill ◽  
Xuemin Zhang ◽  
Ann K. Cashion
Keyword(s):  
Kidney Transplantation ◽  
Weight Gain ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
The Impact ◽  
Factor Concentration

Decreased serum brain-derived neurotrophic factor concentration in young nonobese subjects with low insulin sensitivity

2011 ◽  
Vol 44 (10-11) ◽  
pp. 817-820 ◽  
Author(s):  
Monika Karczewska-Kupczewska ◽  
Marek Strączkowski ◽  
Agnieszka Adamska ◽  
Agnieszka Nikołajuk ◽  
Elżbieta Otziomek ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Factor Concentration

Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reduces energy intake

2007 ◽  
Vol 293 (3) ◽  
pp. R1003-R1012 ◽  
Author(s):  
ChuanFeng Wang ◽  
Eric Bomberg ◽  
Charles Billington ◽  
Allen Levine ◽  
Catherine M. Kotz
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Paraventricular Nucleus ◽  
Neurotrophic Factor ◽  
Body Weight Gain ◽  
Brain Derived Neurotrophic Factor ◽  
Brain Regions ◽  
Hypothalamic Paraventricular Nucleus ◽  
Bdnf Mrna ◽  
Hypothalamic Arcuate Nucleus

Recent studies show that brain-derived neurotrophic factor (BDNF) decreases feeding and body weight after peripheral and ventricular administration. BDNF mRNA and protein, and its receptor tyrosine kinase B (TrkB) are widely distributed in the hypothalamus and other brain regions. However, there are few reports on specific brain sites of actions for BDNF. We evaluated the effect of BDNF in the hypothalamic paraventricular nucleus (PVN) on feeding. BDNF injected unilaterally or bilaterally into the PVN of food-deprived and nondeprived rats significantly decreased feeding and body weight gain within the 0- to 24-h and 24- to 48-h postinjection intervals. Effective doses producing inhibition of feeding behavior did not establish a conditioned taste aversion. PVN BDNF significantly decreased PVN neuropeptide Y (NPY)-induced feeding at 1, 2, and 4 h following injection. BDNF administration in the PVN abolished food-restriction-induced NPY gene expression in the hypothalamic arcuate nucleus. In conclusion, BDNF in the PVN significantly decreases food intake and body weight gain, suggesting that the PVN is an important site of action for BDNF in its effects on energy metabolism. Furthermore, BDNF appears to interact with NPY in its anorectic actions, although a direct effect on NPY remains to be established.

scholarly journals The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met

2010 ◽  
Vol 214 (1) ◽  
pp. 319-328 ◽  
Author(s):  
Bernet M. Elzinga ◽  
Marc L. Molendijk ◽  
Richard C. Oude Voshaar ◽  
Boudewijn A. A. Bus ◽  
Jos Prickaerts ◽  
...  
Keyword(s):  
Childhood Abuse ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
The Impact ◽  
Moderating Role

The role of brain-derived neurotrophic factor (BDNF) gene variants in antipsychotic response and antipsychotic-induced weight gain

2012 ◽  
Vol 39 (1) ◽  
pp. 96-101 ◽  
Author(s):  
Gwyneth C.M. Zai ◽  
Clement C.H. Zai ◽  
Nabilah I. Chowdhury ◽  
Arun K. Tiwari ◽  
Renan P. Souza ◽  
...  
Keyword(s):  
Weight Gain ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Gene Variants ◽  
Bdnf Gene

scholarly journals The impact of dietary tarragon (Artemisia dracunculus) on serum apelin, brain-derived neurotrophic factor, cardiac troponin concentrations and histopathology of liver tissue in laying hens housed at different stocking densities

2020 ◽  
Vol 65 (No. 6) ◽  
pp. 269-279
Author(s):  
B Bayraktar ◽  
E Tekce ◽  
H Kaya ◽  
M Karaalp ◽  
E Turunc
Keyword(s):  
Blood Vessels ◽  
Neurotrophic Factor ◽  
Cardiac Troponin ◽  
Stocking Density ◽  
Brain Derived Neurotrophic Factor ◽  
Egg Laying ◽  
Stress Factors ◽  
Negative Consequences ◽  
Artemisia Dracunculus ◽  
The Impact

Due to its association with several other stress factors (poultry house gases, inadequate ventilation, heat, cold and poor hygiene), the high stocking density is a major stress factor that adversely affects the health and performance of poultry and the quality of the poultry products. Therefore, this experimental study was aimed at analysing the impact of different doses of dietary tarragon (Artemisia dracunculus) on the serum apelin, plasma brain-derived neurotrophic factor (p-BDNF), and cardiac troponin I (cTnI) concentrations, and the correlation between these indicators in laying hens housed at different stocking densities. The aim of this study is to investigate the effects of adding tarragon in different ratios to laying hen rations in the 2<sup>nd</sup> ovulation period on the cTnI, apelin, and BDNF hormone concentrations and the liver histopathology. The experiment was carried out over a period of eight weeks, with 192 Lohman Brown commercial hybrids at 50 weeks of age. Eight groups (four replicates each), composed of laying hens of equal body weight, which were housed at stocking densities of 580 cm<sup>2</sup>/hen and 810 cm<sup>2</sup>/hen and received 0, 1, 5 and 10 mmol/kg of tarragon (Artemisia dracunculus) in the feed, were established. At the end of the trial, 96 of the housed egg-laying hens (3 birds in each subgroup, a total of 12 birds in each group) were randomly selected and blood samples were taken from the vena subcutanea ulnaris. The samples collected were analysed for the apelin, p-BDNF, and cTnI contents. The analysis results demonstrated that tarragon supplementation had no effect on the serum apelin, p-BDNF and cTnI concentrations (P &gt; 0.05). The Sub-Groups ST1, ST1.2, and ST6 presented with severe hyperaemia of the sinusoidal, portal and acinar blood vessels, whilst the hyperaemia of these blood vessels was moderate in Sub-Group ST12. Apelin, BDNF, and cTnI can act as protective factors against negative consequences of stress (e.g., stocking density or heat stress).

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