Neurotrophin-4/5, brain-derived neurotrophic factor, and neurotrophin-3 promote survival of cultured vestibular ganglion neurons and protect them against neurotoxicity of ototoxins

1995 ◽  
Vol 28 (3) ◽  
pp. 330-340 ◽  
Author(s):  
J. Lisa Zheng ◽  
Randall R. Stewart ◽  
Wei-Qiang Gao
Keyword(s):  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Vestibular Ganglion ◽  
Neurotrophin 3 ◽  
Ganglion Neurons

In vivo effects of neurotrophin-3 during sensory neurogenesis

Development ◽  
1996 ◽  
Vol 122 (1) ◽  
pp. 301-307 ◽  
Author(s):  
M. Ockel ◽  
G.R. Lewin ◽  
Y.A. Barde
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Dorsal Root Ganglion Neurons ◽  
Sensory Ganglia ◽  
Nerve Growth ◽  
Neurotrophin 3 ◽  
Ganglion Neurons ◽  
Sensory Neurogenesis

The neurotrophins nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 are structurally related proteins regulating the number of neurons in peripheral ganglia of the nervous system. Increased levels of nerve growth factor or of brain-derived neurotrophic factor selectively prevent normally occurring neuronal death, while the targeted elimination of all three genes decreases neuronal numbers. As previous studies indicated that the lack of neurotrophin-3 affects sensory ganglia already during gangliogenesis, the levels of this neurotrophin were increased during selected periods of chick development. We found that early, but not late, applications of neurotrophin-3 lead to a marked decrease in neuronal numbers in peripheral sensory ganglia. This decrease is not seen with BDNF and does not selectively affect subtypes of dorsal root ganglion neurons. It is accompanied by, and might result from, a decrease in the number of proliferating neuroblasts in sensory ganglia of treated embryos.

Brain-Derived Neurotrophic Factor and Neurotrophin-3 Support the Survival and Neuritogenesis Response of Developing Cochleovestibular Ganglion Neurons

1993 ◽  
Vol 159 (1) ◽  
pp. 266-275 ◽  
Author(s):  
Matias A. Avila ◽  
Isabel Varela-Nieto ◽  
Guillermo Romero ◽  
Jose M. Mato ◽  
Fernando Giraldez ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Neurotrophin 3 ◽  
Ganglion Neurons

Poster #113 BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF), NEUROTROPHIN 3 (NTF3), NEUROTROPHIN 4 (NTF4) AND GLIAL-DERIVED NEUROTROPHIC FACTOR (GDNF) SERUM LEVELS IN SCHIZOPHRENIA

2012 ◽  
Vol 136 ◽  
pp. S132-S133
Author(s):  
Anna Leszczynska-Rodziewicz ◽  
Maria Skibinska ◽  
Pawel Kapelski ◽  
Aleksandra Rajewska-Rager ◽  
Joanna Pawlak ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Serum Levels ◽  
Brain Derived Neurotrophic Factor ◽  
Neurotrophin 3 ◽  
Glial Derived Neurotrophic Factor

Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 levels in human amniotic fluid

1999 ◽  
Vol 181 (5) ◽  
pp. 1225-1230 ◽  
Author(s):  
Christine E. Marx ◽  
Brandon J. Vance ◽  
L.Fredrik Jarskog ◽  
Nancy C. Chescheir ◽  
John H. Gilmore
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Amniotic Fluid ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Human Amniotic Fluid ◽  
Nerve Growth ◽  
Neurotrophin 3
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