scholarly journals Systematic review of gastrostomy complications and outcomes in pediatric cancer and bone marrow transplant

2021 ◽  
Author(s):  
James Evans ◽  
Breeana Gardiner ◽  
Dan Green ◽  
Faith Gibson ◽  
Graeme O'Connor ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Pediatric Cancer ◽  
Marrow Transplant ◽  
Gastrostomy Complications

scholarly journals Systematic review of gastrostomy complications and outcomes in pediatric cancer and bone marrow transplant

2021 ◽  
Author(s):  
James Evans ◽  
Breeana Gardiner ◽  
Dan Green ◽  
Faith Gibson ◽  
Graeme O'Connor ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bone Marrow ◽  
Nutritional Status ◽  
Bone Marrow Transplant ◽  
Pediatric Cancer ◽  
Marrow Transplant ◽  
Nutrition Support ◽  
Disease States ◽  
Pediatric Cancer Patients ◽  
Gastrostomy Complications

Nutrition support is essential in children with cancer, including those undergoing bone marrow transplant (BMT), to reduce the risk of malnutrition and associated deleterious outcomes. Enteral nutrition is more commonly provided via nasogastric than gastrostomy tubes due to safety concerns with the latter in immunocompromised children. This systematic review investigated the incidence and type of complications and outcomes in pediatric cancer patients fed by gastrostomy. Across studies, 54.6% of children developed ≥1 complication, of which 76.6% were classified as minor, 23.4% major. The most frequent complications included inflammation (52% of episodes), infection (42.1%), leakage (22.3%) and granuloma (21%). Evidence regarding infection rates in cancer/BMT patients compared with other disease states was inconclusive. Gastrostomy feeding was associated with improvement or stabilization of nutritional status in 77-92.7% of children. Gastrostomy feeding in this population is safe and effective in stabilizing or improving nutritional status throughout treatment. Complications are frequent but mostly minor.

Quantitative evaluation of post-bone marrow transplant engraftment status using fluorescent-labeled variable number of tandem repeats

2000 ◽  
Vol 05 (2) ◽  
pp. 129-138
Author(s):  
Robert A. Luhm ◽  
Daniel B. Bellissimo ◽  
Arejas J. Uzgiris ◽  
William R. Drobyski ◽  
Martin J. Hessner
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Quantitative Evaluation ◽  
Tandem Repeats ◽  
Marrow Transplant ◽  
Variable Number
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