Improved gradient waveforms for oscillating gradient spin‐echo (OGSE) diffusion tensor imaging

2020 ◽  
Vol 34 (2) ◽  
Author(s):  
Franciszek Hennel ◽  
Eric Seth Michael ◽  
Klaas P. Pruessmann
2017 ◽  
Vol 27 (3) ◽  
pp. 193-201 ◽  
Author(s):  
Fabian Hilbert ◽  
Tobias Wech ◽  
Henning Neubauer ◽  
Simon Veldhoen ◽  
Thorsten Alexander Bley ◽  
...  

Author(s):  
Christian T Stoeck ◽  
Constantin von Deuster ◽  
Martin Genet ◽  
David Atkinson ◽  
Sebastian Kozerke

2014 ◽  
Vol 41 (3) ◽  
pp. 624-632 ◽  
Author(s):  
Brian Noehren ◽  
Anders Andersen ◽  
Thorsten Feiweier ◽  
Bruce Damon ◽  
Peter Hardy

2020 ◽  
Vol 19 (2) ◽  
pp. 159-165
Author(s):  
Takayuki Sakai ◽  
Yasuchika Aoki ◽  
Atsuya Watanabe ◽  
Masami Yoneyama ◽  
Shigehiro Ochi ◽  
...  

Author(s):  
Christian T Stoeck ◽  
Constantin von Deuster ◽  
Nikola Cesarovic ◽  
Martin Genet ◽  
Maximilian Y Emmert ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Valentina Mazzoli ◽  
Kevin Moulin ◽  
Feliks Kogan ◽  
Brian A. Hargreaves ◽  
Garry E. Gold

Diffusion tensor imaging (DTI) measures water diffusion in skeletal muscle tissue and allows for muscle assessment in a broad range of neuromuscular diseases. However, current DTI measurements, typically performed using pulsed gradient spin echo (PGSE) diffusion encoding, are limited to the assessment of non-contracted musculature, therefore providing limited insight into muscle contraction mechanisms and contraction abnormalities. In this study, we propose the use of an oscillating gradient spin echo (OGSE) diffusion encoding strategy for DTI measurements to mitigate the effect of signal voids in contracted muscle and to obtain reliable diffusivity values. Two OGSE sequences with encoding frequencies of 25 and 50 Hz were tested in the lower leg of five healthy volunteers with relaxed musculature and during active dorsiflexion and plantarflexion, and compared with a conventional PGSE approach. A significant reduction of areas of signal voids using OGSE compared with PGSE was observed in the tibialis anterior for the scans obtained in active dorsiflexion and in the soleus during active plantarflexion. The use of PGSE sequences led to unrealistically elevated axial diffusivity values in the tibialis anterior during dorsiflexion and in the soleus during plantarflexion, while the corresponding values obtained using the OGSE sequences were significantly reduced. Similar findings were seen for radial diffusivity, with significantly higher diffusivity measured in plantarflexion in the soleus muscle using the PGSE sequence. Our preliminary results indicate that DTI with OGSE diffusion encoding is feasible in human musculature and allows to quantitatively assess diffusion properties in actively contracting skeletal muscle. OGSE holds great potential to assess microstructural changes occurring in the skeletal muscle during contraction, and for non-invasive assessment of contraction abnormalities in patients with muscle diseases.


2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Jun-Ya Kaimori ◽  
Yoshitaka Isaka ◽  
Masaki Hatanaka ◽  
Satoko Yamamoto ◽  
Naotsugu Ichimaru ◽  
...  

NeuroImage ◽  
2008 ◽  
Vol 42 (4) ◽  
pp. 1451-1462 ◽  
Author(s):  
Minzhi Gui ◽  
Huiling Peng ◽  
John D. Carew ◽  
Maciej S. Lesniak ◽  
Konstantinos Arfanakis

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