scholarly journals Rapid single scan ramped hybrid‐encoding for bicomponent T2* mapping in a human knee joint: A feasibility study

2020 ◽  
Vol 33 (11) ◽  
Author(s):  
Hyungseok Jang ◽  
Alan B. McMillan ◽  
Yajun Ma ◽  
Saeed Jerban ◽  
Eric Y. Chang ◽  
...  
Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1476
Author(s):  
Oliver Said ◽  
Justus Schock ◽  
Daniel Benjamin Abrar ◽  
Philipp Schad ◽  
Christiane Kuhl ◽  
...  

Stress MRI brings together mechanical loading and MRI in the functional assessment of cartilage and meniscus, yet lacks basic scientific validation. This study assessed the response-to-loading patterns of cartilage and meniscus incurred by standardized compartmental varus and valgus loading of the human knee joint. Eight human cadaveric knee joints underwent imaging by morphologic (i.e., proton density-weighted fat-saturated and 3D water-selective) and quantitative (i.e., T1ρ and T2 mapping) sequences, both unloaded and loaded to 73.5 N, 147.1 N, and 220.6 N of compartmental pressurization. After manual segmentation of cartilage and meniscus, morphometric measures and T2 and T1ρ relaxation times were quantified. CT-based analysis of joint alignment and histologic and biomechanical tissue measures served as references. Under loading, we observed significant decreases in cartilage thickness (p < 0.001 (repeated measures ANOVA)) and T1ρ relaxation times (p = 0.001; medial meniscus, lateral tibia; (Friedman test)), significant increases in T2 relaxation times (p ≤ 0.004; medial femur, lateral tibia; (Friedman test)), and adaptive joint motion. In conclusion, varus and valgus stress MRI induces meaningful changes in cartilage and meniscus secondary to compartmental loading that may be assessed by cartilage morphometric measures as well as T2 and T1ρ mapping as imaging surrogates of tissue functionality.


2018 ◽  
Vol 00 (1) ◽  
pp. 109-118
Author(s):  
Enas Y. Abdullah ◽  
◽  
Naktal Moid Edan ◽  
Athraa N. Kadhim ◽  
◽  
...  

1985 ◽  
Vol 18 (7) ◽  
pp. 541
Author(s):  
Ph. Edixhoven ◽  
R. Huiskes ◽  
Th.J.G. van Rens ◽  
T.J.J.H. Slooff

2014 ◽  
Vol 15 (5) ◽  
pp. 7250-7265 ◽  
Author(s):  
Congming Zhang ◽  
Xiaochun Wei ◽  
Chongwei Chen ◽  
Kun Cao ◽  
Yongping Li ◽  
...  

2019 ◽  
Vol 11 (1) ◽  
pp. 27-30
Author(s):  
Gábor Péter Balassa

Abstract The necessity for the knee prosthesis is confirmed by the large increase in the number of patients suffering from arthrosis, which is a present-day disease. Despite this need, there doesn’t exist an optimal knee prosthesis. Nowadays the development of the knee prostheses is progressing. It is very difficult to define the required geometry with traditional methods, because the movement conditions to be created by the prostheses should be similar to the movements of the human knee. During previous research the biomechanical research team of the Szent István University occupied with experimental measurements of the healthy human knee joint movement. In this paper I would like to introduce a method of prosthesis geometry development. As a result, a knee prosthesis geometry has been created which is approaching the movement form of the real human knee joint.


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