A review of diffusion MRI of typical white matter development from early childhood to young adulthood

2017 ◽  
Vol 32 (4) ◽  
pp. e3778 ◽  
Author(s):  
Catherine Lebel ◽  
Sarah Treit ◽  
Christian Beaulieu
Keyword(s):  
Early Childhood ◽  
White Matter ◽  
Young Adulthood ◽  
Diffusion Mri ◽  
White Matter Development

White matter development during adolescence as shown by diffusion MRI

2010 ◽  
Vol 72 (1) ◽  
pp. 16-25 ◽  
Author(s):  
Vincent J. Schmithorst ◽  
Weihong Yuan
Keyword(s):  
White Matter ◽  
Diffusion Mri ◽  
White Matter Development

scholarly journals Association between breastfeeding during infancy and white matter microstructure in early childhood

2021 ◽  
Author(s):  
Preeti Kar ◽  
Jess E. Reynolds ◽  
Melody N. Grohs ◽  
Rhonda C. Bell ◽  
Megan Jarman ◽  
...  
Keyword(s):  
Early Childhood ◽  
White Matter ◽  
Diffusion Tensor ◽  
Total Duration ◽  
Sociodemographic Factors ◽  
Typically Developing ◽  
Brain White Matter ◽  
White Matter Microstructure ◽  
White Matter Development ◽  
Exclusive Or

Introduction: Associations between breastfeeding and brain development, in the context of child, perinatal, and sociodemographic variables, remain unclear. This study investigates whether exclusive breastfeeding for the first 6 months and total duration of any breastfeeding are associated with brain white matter microstructure in young children. Methods: This study included a sample of 83 mothers and 85 typically developing children (42 males). Children underwent their first diffusion tensor imaging scan between ages 2.34-6.97 years; some children returned multiple times, providing a total of 331 datasets. Feeding information was collected from the mothers at 3, 6, and 12 months postpartum and at their child's scan to calculate breastfeeding status at 6 months (exclusive or not) as well as total duration of any breastfeeding. Linear regression was used to investigate associations between breastfeeding exclusivity/duration and fractional anisotropy (FA, a measure sensitive to myelination/axonal packing/fibre coherence) for the whole brain and 10 individual white matter tracts. Results: Breastfeeding exclusivity and duration were associated with global and regional white matter microstructure, even after controlling for perinatal and sociodemographic factors. Greater exclusivity was associated with higher FA in females and lower FA in males. Conclusions: These findings suggest white matter differences associated with breastfeeding that differ by sex. These may stem from different trajectories in white matter development between males and females in early childhood and suggest possible long-term white matter differences associated with breastfeeding.

scholarly journals Global and regional white matter development in early childhood

NeuroImage ◽  
2019 ◽  
Vol 196 ◽  
pp. 49-58 ◽  
Author(s):  
Jess E. Reynolds ◽  
Melody N. Grohs ◽  
Deborah Dewey ◽  
Catherine Lebel
Keyword(s):  
Early Childhood ◽  
White Matter ◽  
White Matter Development

scholarly journals Characterizing longitudinal white matter development during early childhood

2014 ◽  
Vol 220 (4) ◽  
pp. 1921-1933 ◽  
Author(s):  
Douglas C. Dean ◽  
Jonathan O’Muircheartaigh ◽  
Holly Dirks ◽  
Nicole Waskiewicz ◽  
Lindsay Walker ◽  
...  
Keyword(s):  
Early Childhood ◽  
White Matter ◽  
White Matter Development

924. Socioeconomic Status in Early Childhood Predicts White Matter Integrity in Young Adulthood

2017 ◽  
Vol 81 (10) ◽  
pp. S373-S374
Author(s):  
Sarah Lichenstein ◽  
Daniel Shaw ◽  
Stephanie Sitnick ◽  
Erika Forbes
Keyword(s):  
Socioeconomic Status ◽  
Early Childhood ◽  
White Matter ◽  
Young Adulthood ◽  
White Matter Integrity

scholarly journals Global and regional white matter development in early childhood

2019 ◽  
Author(s):  
Jess E. Reynolds ◽  
Melody N. Grohs ◽  
Deborah Dewey ◽  
Catherine Lebel
Keyword(s):  
Early Childhood ◽  
White Matter ◽  
Brain Injuries ◽  
Diffusion Tensor ◽  
Developmental Trajectories ◽  
Early Adulthood ◽  
Mean Diffusivity ◽  
Age Related ◽  
White Matter Development ◽  
Age Range

AbstractWhite matter development continues throughout childhood and into early adulthood, but few studies have examined early childhood, and the specific trajectories and regional variation in this age range remain unclear. The aim of this study was to characterize developmental trajectories and sex differences of white matter in typically developing young children. Three hundred and ninety-six diffusion tensor imaging datasets from 120 children (57 male) aged 2-8 years were analyzed using tractography. Fractional anisotropy (FA) increased and mean diffusivity (MD) decreased in all white matter tracts by 5-15% over the 6-year period, likely reflecting increases in myelination and axonal packing. Males showed steeper slopes in a number of brain areas. Overall, early childhood is associated with substantial development of all white matter and appears to be an important period for the development of occipital and limbic connections, which showed the largest changes. This study provides a detailed characterization of age-related white matter changes in early childhood, offering baseline data that can be used to understand cognitive and behavioural development, as well as to identify deviations from normal development in children with various diseases, disorders, or brain injuries.

scholarly journals Investigating white matter development in infancy and early childhood using myelin water faction and relaxation time mapping

NeuroImage ◽  
2012 ◽  
Vol 63 (3) ◽  
pp. 1038-1053 ◽  
Author(s):  
Sean C.L. Deoni ◽  
Douglas C. Dean ◽  
Jonathan O'Muircheartaigh ◽  
Holly Dirks ◽  
Beth A. Jerskey
Keyword(s):  
Early Childhood ◽  
Relaxation Time ◽  
White Matter ◽  
White Matter Development ◽  
Infancy And Early Childhood

scholarly journals A Longitudinal Study of White Matter Development in Relation to Changes in Autism Severity Across Early Childhood

2020 ◽  
Author(s):  
Derek Sayre Andrews ◽  
Joshua K. Lee ◽  
Danielle Jenine Harvey ◽  
Einat Waizbard-Bartov ◽  
Marjorie Solomon ◽  
...  
Keyword(s):  
Early Childhood ◽  
Longitudinal Study ◽  
White Matter ◽  
Autism Severity ◽  
White Matter Development

Clustering of short association white matter fibers calculated from diffusion MRI

2014 ◽  
Author(s):  
C. Roman ◽  
D. Le Bihan ◽  
C. Poupon ◽  
P. Guevara ◽  
A. Lebois ◽  
...  
Keyword(s):  
White Matter ◽  
Diffusion Mri
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