scholarly journals T2mapping provides multiple approaches for the characterization of muscle involvement in neuromuscular diseases: a cross-sectional study of lower leg muscles in 5-15-year-old boys with Duchenne muscular dystrophy

2012 ◽  
Vol 26 (3) ◽  
pp. 320-328 ◽  
Author(s):  
Ishu Arpan ◽  
Sean C. Forbes ◽  
Donovan J. Lott ◽  
Claudia R. Senesac ◽  
Michael J. Daniels ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Neuromuscular Diseases ◽  
Lower Leg ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Muscle Involvement ◽  
Leg Muscles

scholarly journals The burden of Duchenne muscular dystrophy: An international, cross-sectional study

Neurology ◽  
2014 ◽  
Vol 83 (6) ◽  
pp. 529-536 ◽  
Author(s):  
E. Landfeldt ◽  
P. Lindgren ◽  
C. F. Bell ◽  
C. Schmitt ◽  
M. Guglieri ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Evaluation of speed-accuracy trade-off in a computer task to identify motor difficulties in individuals with Duchenne Muscular Dystrophy - A cross-sectional study

2020 ◽  
Vol 96 ◽  
pp. 103541
Author(s):  
Talita Dias da Silva ◽  
Denise Cardoso Ribeiro-Papa ◽  
Shelly Coe ◽  
Silvia Regina Pinheiro Malheiros ◽  
Thais Massetti ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Trade Off ◽  
Motor Difficulties ◽  
Speed Accuracy

scholarly journals Influence of Different Types of Corticosteroids on Heart Rate Variability of Individuals with Duchenne Muscular Dystrophy—A Pilot Cross Sectional Study

Life ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 752
Author(s):  
Rodrigo Martins Dias ◽  
Rosangela Akemi Hoshi ◽  
Luiz Carlos Marques Vanderlei ◽  
Carlos Bandeira de Mello Monteiro ◽  
Mayra Priscila Boscolo Alvarez ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Cross Sectional Study ◽  
Control Group ◽  
Autonomic Modulation ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cardiac Autonomic Modulation

Individuals with Duchenne Muscular Dystrophy (DMD) have an impairment of cardiac autonomic function categorized by parasympathetic reduction and sympathetic predominance. The objective of this study was to assess the cardiac autonomic modulation of individuals with DMD undergoing therapy with Prednisone/Prednisolone and Deflazacort and compare with individuals with DMD without the use of these medications and a typically developed control group. Methods: A cross-sectional study was completed, wherein 40 boys were evaluated. The four treatment groups were: Deflazacort; Prednisone/Prednisolone; no corticoid use; and typical development. Heart Rate Variability (HRV) was investigated via linear indices (Time Domain and Frequency Domain) and non-linear indices Results: The results of this study revealed that individuals with DMD undertaking pharmacotherapies with Prednisolone demonstrated HRV comparable to the Control Typically Developed (CTD) group. In contrast, individuals with DMD undergoing pharmacotherapies with Deflazacort achieved lower HRV, akin to individuals with DMD without any medications, as demonstrated in the metrics: RMSSD; LF (n.u.), HF (n.u.), LF/HF; SD1, α1, and α1/α2, and a significant effect for SD1/SD2; %DET and Ratio; Shannon Entropy, 0 V%, 2 LV% and 2 ULV%. Conclusions: Corticosteroids have the potential to affect the cardiac autonomic modulation in adolescents with DMD. The use of Prednisone/Prednisolone appears to promote improved responses in terms of sympathovagal activity as opposed to Deflazacort.

scholarly journals Health-related quality of life in patients with Duchenne muscular dystrophy: a multinational, cross-sectional study

2015 ◽  
Vol 58 (5) ◽  
pp. 508-515 ◽  
Author(s):  
Erik Landfeldt ◽  
Peter Lindgren ◽  
Christopher F Bell ◽  
Michela Guglieri ◽  
Volker Straub ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Sectional Study ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related
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