scholarly journals High-resolution human cervical spinal cord imaging at 7 T

2011 ◽  
Vol 25 (7) ◽  
pp. 891-899 ◽  
Author(s):  
E. E. Sigmund ◽  
G. A. Suero ◽  
C. Hu ◽  
K. McGorty ◽  
D. K. Sodickson ◽  
...  
Keyword(s):  
Spinal Cord ◽  
High Resolution ◽  
Cervical Spinal Cord ◽  
Spinal Cord Imaging

scholarly journals Comparison of Three-Dimensional Micro-CT Angiography of Cervical Spinal Cord between Two Contrast Agents

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Yapu Liu ◽  
Qi Liu ◽  
Zhou Yang ◽  
Junyu Lin ◽  
Xiuhua Wu ◽  
...  
Keyword(s):  
Spinal Cord ◽  
High Resolution ◽  
Contrast Agents ◽  
Lead Oxide ◽  
Barium Sulfate ◽  
Cervical Spinal Cord ◽  
Sulfate Group ◽  
Micro Ct ◽  
Low Resolution ◽  
Oxide Group

Purpose. Barium sulfate and lead oxide are commonly used for angiographic studies, but there is no report on the comparison of two contrast agents in angiography of cervical spinal cord. This study was aimed to compare the microvascular architecture of cervical spinal cord in rats after angiography with the barium sulfate agent to the lead oxide agent. Methods. Twelve adult Sprague-Dawley rats were randomly divided into the barium sulfate group (n=6) and the lead oxide group (n=6). Each rat was perfused under the same protocol using either two contrast agents. The angiography was evaluated with the vascular number at different ranks. The cervical spinal cord samples were scanned using micro-CT with low resolution and high resolution. The microvascular parameters, including ratio of vascular volume to tissue volume (VV/TV), vascular number (V.N), diameter (V.Dm), separation (V.Sp), connectivity density (Conn.D), structure model index (SMI), percentage, and volume of vessels at different diameters were measured. Results. The perfusion was better in the barium sulfate group, with more blood vessel trees of rank II and III visible compared to the lead oxide group. Low-resolution micro-CT analysis showed no difference in microvascular parameters except SMI between the two groups. High-resolution micro-CT analysis results showed that V.N and Conn.D of barium sulfate group were 60% and 290% more than those of the lead oxide group; however, V.Sp was 41% less than the lead oxide group. The percentage of vessels with diameter of 10 μm and 20 μm, and the volume of vessels with diameter of less than 100 μm was higher in the barium sulfate group than in the lead oxide group. The SMI index in the barium sulfate group was higher than that in the lead oxide group at both low resolution and high resolution. Conclusions. Compared with lead oxide, barium sulfate is more suitable for perfusion of cervical spinal cord microvessels, and cheap and nontoxic with high resolution.

scholarly journals Magnetic resonance imaging of the cervical spinal cord in multiple sclerosis at 7T

2015 ◽  
Vol 22 (3) ◽  
pp. 320-328 ◽  
Author(s):  
Adrienne N Dula ◽  
Siddharama Pawate ◽  
Richard D Dortch ◽  
Robert L Barry ◽  
Kristen M George-Durrett ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Spinal Cord ◽  
White Matter ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Healthy Volunteers ◽  
Cervical Spinal Cord ◽  
Resonance Imaging ◽  
Lower Field

Background: The clinical course of multiple sclerosis (MS) is mainly attributable to cervical and upper thoracic spinal cord dysfunction. High-resolution, 7T anatomical imaging of the cervical spinal cord is presented. Image contrast between gray/white matter and lesions surpasses conventional, clinical T1- and T2-weighted sequences at lower field strengths. Objective: To study the spinal cord of healthy controls and patients with MS using magnetic resonance imaging at 7T. Methods: Axial (C2–C5) T1- and T2*-weighted and sagittal T2*-/spin-density-weighted images were acquired at 7T in 13 healthy volunteers (age 22–40 years), and 15 clinically diagnosed MS patients (age 19–53 years, Extended Disability Status Scale, (EDSS) 0–3) in addition to clinical 3T scans. In healthy volunteers, a high-resolution multi-echo gradient echo scan was obtained over the same geometry at 3T. Evaluation included signal and contrast to noise ratios and lesion counts for healthy and patient volunteers, respectively. Results/conclusion: High-resolution images at 7T exceeded resolutions reported at lower field strengths. Gray and white matter were sharply demarcated and MS lesions were more readily visualized at 7T compared to clinical acquisitions, with lesions apparent at both fields. Nerve roots were clearly visualized. White matter lesion counts averaged 4.7 vs 3.1 (52% increase) per patient at 7T vs 3T, respectively ( p=0.05).

Eight-channel decoupled array for cervical spinal cord imaging at 3T: six-channel posterior and two-channel anterior array coil

2016 ◽  
Vol 46B (2) ◽  
pp. 90-99 ◽  
Author(s):  
Nabraj Sapkota ◽  
Bijaya Thapa ◽  
YouJung Lee ◽  
Taeho Kim ◽  
Erica F. Bisson ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Array Coil ◽  
Spinal Cord Imaging

scholarly journals Nineteen-channel receive array and four-channel transmit array coil for cervical spinal cord imaging at 7T

2014 ◽  
Vol 72 (1) ◽  
pp. spcone-spcone
Author(s):  
Wei Zhao ◽  
Julien Cohen-Adad ◽  
Jonathan R. Polimeni ◽  
Boris Keil ◽  
Bastien Guerin ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Receive Array ◽  
Array Coil ◽  
Spinal Cord Imaging

scholarly journals Visualization of the Cervical Spinal Cord with FDG and High-Resolution PET

1998 ◽  
Vol 22 (3) ◽  
pp. 487-491 ◽  
Author(s):  
Yoko Kamoto ◽  
Norihiro Sadato ◽  
Yoshiharu Yonekura ◽  
Tatsuro Tsuchida ◽  
Hidemasa Uematsu ◽  
...  
Keyword(s):  
Spinal Cord ◽  
High Resolution ◽  
Cervical Spinal Cord
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