Towards compartment size estimationin vivobased on double wave vector diffusion weighting

2011 ◽  
Vol 24 (10) ◽  
pp. 1422-1432 ◽  
Author(s):  
Martin A. Koch ◽  
Jürgen Finsterbusch
2015 ◽  
Vol 1 (1) ◽  
pp. 240-244 ◽  
Author(s):  
Patricia Ulloa ◽  
Viktor Wottschel ◽  
Martin A. Koch

AbstractThe use of two independent diffusion periods between excitation and acquisition, known as double wave vector (DWV) diffusion-weighting or double diffusion encoding, was proven to yield structural information that it is otherwise not easily available in vivo. Comparing the signal difference between relative diffusion gradient orientations, the antiparallel-parallel and the parallel-perpendicular differences yield information on pore size and shape, respectively. However, results in vivo provided larger pore sizes than expected for axons in the corticospinal tract. This study exploits DWV sensitivity to pore shape and aims to obtain information on the extracellular contributions to the DWV pore size results presented here. The in vivo DWV experiments resulted in a positive parallel-perpendicular difference which is consistent with an irregularly shaped pore dominating the origin of the signal.


Author(s):  
H. S. Kim ◽  
S. S. Sheinin

The importance of image simulation in interpreting experimental lattice images is well established. Normally, in carrying out the required theoretical calculations, only zero order Laue zone reflections are taken into account. In this paper we assess the conditions for which this procedure is valid and indicate circumstances in which higher order Laue zone reflections may be important. Our work is based on an analysis of the requirements for obtaining structure images i.e. images directly related to the projected potential. In the considerations to follow, the Bloch wave formulation of the dynamical theory has been used.The intensity in a lattice image can be obtained from the total wave function at the image plane is given by: where ϕg(z) is the diffracted beam amplitide given by In these equations,the z direction is perpendicular to the entrance surface, g is a reciprocal lattice vector, the Cg(i) are Fourier coefficients in the expression for a Bloch wave, b(i), X(i) is the Bloch wave excitation coefficient, ϒ(i)=k(i)-K, k(i) is a Bloch wave vector, K is the electron wave vector after correction for the mean inner potential of the crystal, T(q) and D(q) are the transfer function and damping function respectively, q is a scattering vector and the summation is over i=l,N where N is the number of beams taken into account.


2021 ◽  
Vol 126 (8) ◽  
Author(s):  
Wenguo Zhu ◽  
Huadan Zheng ◽  
Yongchun Zhong ◽  
Jianhui Yu ◽  
Zhe Chen

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