Efficacy of fesoterodine fumarate (8 mg) in neurogenic detrusor overactivity due to spinal cord lesion or multiple sclerosis: A prospective study

2021 ◽  
Author(s):  
Charalampos Konstantinidis ◽  
Michael Samarinas ◽  
Moira Tzitzika ◽  
Zisis Kratiras ◽  
Georgios Panagiotakopoulos ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Spinal Cord ◽  
Prospective Study ◽  
Detrusor Overactivity ◽  
Spinal Cord Lesion ◽  
Neurogenic Detrusor Overactivity ◽  
A Prospective Study ◽  
Cord Lesion

scholarly journals LBA01-07 EFFICACY OF FESOTERODINE FUMARATE IN NEUROGENIC DETRUSOR OVERACTIVITY DUE TO SPINAL CORD LESION OR MULTIPLE SCLEROSIS – A PROSPECTIVE STUDY

2021 ◽  
Vol 206 (Supplement 3) ◽  
Author(s):  
Charalampos Konstantinidis ◽  
Michael Samarinas ◽  
Charalampos Thomas ◽  
Moira Tzitzika ◽  
Konstantinos Giannitsas ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Spinal Cord ◽  
Prospective Study ◽  
Detrusor Overactivity ◽  
Spinal Cord Lesion ◽  
Neurogenic Detrusor Overactivity ◽  
A Prospective Study ◽  
Cord Lesion

A DTI study of the spinal cord lesion in patients with multiple sclerosis during the follow-up after relapse

2016 ◽  
Vol 116 (2. Vyp. 2) ◽  
pp. 21 ◽  
Author(s):  
S. N. Morozova ◽  
V. V. Bryukhov ◽  
O. V. Trifonova ◽  
E. I. Kremneva ◽  
M. V. Krotenkova
Keyword(s):  
Multiple Sclerosis ◽  
Spinal Cord ◽  
Spinal Cord Lesion ◽  
Cord Lesion

Increasing the sensitivity of MRI for the detection of multiple sclerosis lesions by long axial coverage of the spinal cord: a prospective study in 119 patients

2016 ◽  
Vol 264 (2) ◽  
pp. 341-349 ◽  
Author(s):  
Michael O. Breckwoldt ◽  
Johann Gradl ◽  
Stefan Hähnel ◽  
Thomas Hielscher ◽  
Brigitte Wildemann ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Spinal Cord ◽  
Prospective Study ◽  
A Prospective Study

scholarly journals Grey matter involvement by focal cervical spinal cord lesions is associated with progressive multiple sclerosis

2015 ◽  
Vol 22 (7) ◽  
pp. 910-920 ◽  
Author(s):  
Hugh Kearney ◽  
Katherine A Miszkiel ◽  
Marios C Yiannakas ◽  
Daniel R Altmann ◽  
Olga Ciccarelli ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Spinal Cord ◽  
Grey Matter ◽  
Cervical Spinal Cord ◽  
Spinal Cord Lesion ◽  
Cervical Cord ◽  
Focal Lesions ◽  
Lateral Column ◽  
Cord Lesion

Background: The in vivo relationship of spinal cord lesion features with clinical course and function in multiple sclerosis (MS) is poorly defined. Objective: The objective of this paper is to investigate the associations of spinal cord lesion features on MRI with MS subgroup and disability. Methods: We recruited 120 people: 25 clinically isolated syndrome, 35 relapsing–remitting (RR), 30 secondary progressive (SP), and 30 primary progressive (PP) MS. Disability was measured using the Expanded Disability Status Scale. We performed 3T axial cervical cord MRI, using 3D-fast-field-echo and phase-sensitive-inversion-recovery sequences. Both focal lesions and diffuse abnormalities were recorded. Focal lesions were classified according to the number of white matter (WM) columns involved and whether they extended to grey matter (GM). Results: The proportion of patients with focal lesions involving at least two WM columns and extending to GM was higher in SPMS than in RRMS ( p = 0.03) and PPMS ( p = 0.015). Diffuse abnormalities were more common in both PPMS and SPMS, compared with RRMS (OR 6.1 ( p = 0.002) and 5.7 ( p = 0.003), respectively). The number of lesions per patient involving both the lateral column and extending to GM was independently associated with disability ( p < 0.001). Conclusions: More extensive focal cord lesions, extension of lesions to GM, and diffuse abnormalities are associated with progressive MS and disability.

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