Does traditional pharmacotherapy augment behavioral modification in the treatment of nocturia?

2021 ◽  
Author(s):  
Connelly D. Miller ◽  
Thomas F. Monaghan ◽  
Dennis J. Robins ◽  
Jeffrey P. Weiss
Keyword(s):  
Behavioral Modification

Prevention of Urinary Incontinence by Behavioral Modification Program: A Randomized, Controlled Trial Among Older Women in the Community

2004 ◽  
Vol 171 (3) ◽  
pp. 1165-1171 ◽  
Author(s):  
ANANIAS C. DIOKNO ◽  
CAROLYN M. SAMPSELLE ◽  
A. REGULA HERZOG ◽  
T.E. RAGHUNATHAN ◽  
SANDRA HINES ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Urinary Incontinence ◽  
Older Women ◽  
Controlled Trial ◽  
Behavioral Modification ◽  
Randomized Controlled

1963 EFFECT OF SYSTEMATIZED BEHAVIORAL MODIFICATION PROGRAM FOR NOCTURIA: A PROSPECTIVE STUDY

2011 ◽  
Vol 185 (4S) ◽  
Author(s):  
Sung Yong Cho ◽  
Sang Lim Lee ◽  
Sun Ho Min ◽  
Soo Woong Kim ◽  
Jae-Seung Paick ◽  
...  
Keyword(s):  
Prospective Study ◽  
Behavioral Modification ◽  
A Prospective Study

Dissociation of Appetitive Overexpectation and Extinction in the Infralimbic Cortex

2018 ◽  
Vol 29 (9) ◽  
pp. 3687-3701 ◽  
Author(s):  
Belinda P P Lay ◽  
Melissa Nicolosi ◽  
Alexandra A Usypchuk ◽  
Guillem R Esber ◽  
Mihaela D Iordanova
Keyword(s):  
Behavioral Change ◽  
Reward Learning ◽  
Behavioral Modification ◽  
Test Drug ◽  
Infralimbic Cortex ◽  
Stimulus Response ◽  
Conditioned Responses ◽  
Conditioned Responding ◽  
Drug Free

Abstract Behavioral change is paramount to adaptive behavior. Two ways to achieve alterations in previously established behavior are extinction and overexpectation. The infralimbic (IL) portion of the medial prefrontal cortex controls the inhibition of previously established aversive behavioral responses in extinction. The role of the IL cortex in behavioral modification in appetitive Pavlovian associations remains poorly understood. Here, we seek to determine if the IL cortex modulates overexpectation and extinction of reward learning. Using overexpectation or extinction to achieve a reduction in behavior, the present findings uncover a dissociable role for the IL cortex in these paradigms. Pharmacologically inactivating the IL cortex left overexpectation intact. In contrast, pre-training manipulations in the IL cortex prior to extinction facilitated the reduction in conditioned responding but led to a disrupted extinction retrieval on test drug-free. Additional studies confirmed that this effect is restricted to the IL and not dependent on the dorsally-located prelimbic cortex. Together, these results show that the IL cortex underlies extinction but not overexpectation-driven reduction in behavior, which may be due to regulating the expression of conditioned responses influenced by stimulus–response associations rather than stimulus–stimulus associations.

scholarly journals Nocturia: consequences, classification, and management

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 1627 ◽  
Author(s):  
Noam D. Fine ◽  
Jeffrey P. Weiss ◽  
Alan J. Wein
Keyword(s):  
Medical Therapy ◽  
Bladder Capacity ◽  
Individual Case ◽  
Systemic Diseases ◽  
Behavioral Modification ◽  
Nocturnal Polyuria ◽  
Quality Of Sleep ◽  
Limited Efficacy ◽  
Appropriate Therapy

Nocturia is a widespread condition that can negatively impact quality of sleep and overall health. This condition is multifactorial in nature and is best approached through the analysis of frequency volume charts. Through these charts, clinicians may classify each individual case of nocturia into one of four distinct categories: global polyuria, nocturnal polyuria, reduced bladder capacity, and mixed. Treatments should then be tailored to each individual based upon the category of their nocturia. In some cases, appropriate therapy will consist of behavioral modification techniques or addressing underlying systemic diseases. In other cases, medical therapy may be necessary, but, to date, medications have shown limited efficacy at treating nocturia.

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