A systematic review and meta‐synthesis of qualitative studies on pelvic organ prolapse for the development of core outcome sets

2020 ◽  
Vol 39 (3) ◽  
pp. 880-889
Author(s):  
Maria Patricia Rada ◽  
Stephanie Jones ◽  
Gabriele Falconi ◽  
Jorge Milhem Haddad ◽  
Cornelia Betschart ◽  
...  
2019 ◽  
Author(s):  
Stergios Doumouchtsis ◽  
Maria Patricia Rada ◽  
Vasilios Pergialiotis ◽  
Gabriele Falconi ◽  
Jorge Milhem Haddad ◽  
...  

Abstract Background The high prevalence of symptomatic pelvic organ prolapse (POP) and the women's lifetime risk of requiring surgery, as well as the significant impact of POP on women’s health related quality of life has resulted in a variety of studies on POP interventions. A wide variety of outcomes have been reported across randomized trials evaluating interventions for POP and various outcome measures have been used. Such variation leads to a limited value of research to provide reliable evidence-based data for clinical practice guidance. The development and use of a core outcome set (COS) would help to address these issues ensuring outcomes important to all stakeholders, primarily women with POP. We aim to produce, disseminate and implement a COS for POP. Methods A steering group within the CHORUS, an International Collaboration for Harmonising Outcomes, Research and Standards in Urogynaecology and Women’s Health will guide the development of this COS. Systematic reviews of trials that reported outcomes and outcome measures on interventions for POP will form the basis for the creation of an outcome inventory. Core outcome selection process will be performed using an international, multi-perspective, online Delphi survey. The modified Delphi method encourages stakeholder group agreement towards consensus core outcomes through repeated reflection and rescoring of items. Discussion Dissemination and implementation of the resulting COS within an international context will be promoted. An embedded COS for POP within future studies will most likely be reflected by an increased value of research that provides guidance for clinical practice. The paradigm of the COS development could further inform research priorities in POP treatments, and support clinical guidelines development and better patient care. KEYWORDS: core outcome sets, outcome measures, pelvic organ prolapse, Delphi survey, randomized trials.


2017 ◽  
Vol 124 (10) ◽  
pp. 1481-1489 ◽  
Author(s):  
JMN Duffy ◽  
R Rolph ◽  
C Gale ◽  
M Hirsch ◽  
KS Khan ◽  
...  

2019 ◽  
Vol 14 (2) ◽  
pp. 7-21
Author(s):  
Shishir Paudel ◽  
Anisha Chalise ◽  
Ganesh Dangal ◽  
Tulsi Ram Bhandari ◽  
Gehanath Baral

Aims: This review was done to identify the reported prevalence rate of pelvic organ prolapse among the different world populations. Methods: Systematic review of Pelvic Organ Prolapse (POP) using the PRISMA checklist; PubMed database was searched on reportingthe prevalence of POP and its management measures in January 2020. Medical Subject Headings (MeSH) like "Pelvic Organ Prolapse"OR "Uterine Prolapse" OR “Vaginal Wall Prolapse” OR "Cystocele"AND "Prevalence [key word/s]" were used. Additional articles were identified through the reference list of the retrieved articles. Results: Out of 91 screened articles, 46 full articles were eligible and only 15 satisfied by selection criteria for the systematic review.The methodological score rated for the quality of studies is 4.5±1.7 (range=2-7) out of 8 points. The mean prevalence of POP diagnosis was 40%; with 42.44% in low and lower-middle-income countries,and 35.56%in upper-middle and high-income countries. Increasing age and parity, body mass indexand fetal macrosomia were found to be the significant risk factors irrespective of the country’s economy. Conclusions:The low and lower-income countries have almost twice the burden of prolapse than the countries of the higher economy. The major risk factors associated with prolapse remain common in all countries irrespective of national income or development.  


2020 ◽  
Vol 39 (7) ◽  
pp. 1912-1921
Author(s):  
Suelene Costa Albuquerque Coelho ◽  
Luiz Gustavo Oliveira Brito ◽  
Camila Carvalho Araujo ◽  
Cássia Raquel Teatin Juliato

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