scholarly journals Early sacral neuromodulation ameliorates urinary bladder function and structure in complete spinal cord injury minipigs

2019 ◽  
Vol 39 (2) ◽  
pp. 586-593 ◽  
Author(s):  
Elena E. Keller ◽  
Irina Patras ◽  
Ioan Hutu ◽  
Karin Roider ◽  
Karl‐Dietrich Sievert ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Urinary Bladder ◽  
Sacral Neuromodulation ◽  
Bladder Function ◽  
Cord Injury ◽  
Complete Spinal Cord Injury

Effects of Sacral Neuromodulation on Isolated Urinary Bladder Function in a Rat Model of Spinal Cord Injury

2014 ◽  
Vol 18 (1) ◽  
pp. 67-75 ◽  
Author(s):  
Şükrü Kumsar ◽  
Ulya Keskin ◽  
Alaaddin Akay ◽  
Uğur Taylan Bilgilisoy ◽  
Ş. Remzi Erdem ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Urinary Bladder ◽  
Rat Model ◽  
Sacral Neuromodulation ◽  
Bladder Function ◽  
Cord Injury

C29 Brain activity associated with urinary bladder filling in patiens with a complete spinal cord injury

2013 ◽  
Vol 12 (4) ◽  
pp. e1137, C29a-e1137, C29b
Author(s):  
P. Holý ◽  
J. Krhut ◽  
J. Tintera ◽  
K. Bilková ◽  
R. Zachoval ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Urinary Bladder ◽  
Brain Activity ◽  
Bladder Filling ◽  
Cord Injury ◽  
Complete Spinal Cord Injury

Towards a Structurally Based Constitutive Model of Urinary Bladder Wall Tissue Remodeling After Spinal Cord Injury

2008 ◽  
Author(s):  
Silvia Wognum ◽  
Michael S. Sacks
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Urinary Bladder ◽  
Constitutive Model ◽  
Bladder Wall ◽  
Experimental Studies ◽  
Bladder Function ◽  
Biomechanical Behavior ◽  
Cord Injury ◽  
Underlying Mechanisms

Spinal cord injury (SCI) is accompanied by urologic complications, characterized by two phases (early areflexic phase and late hyperreflexic phase), where the routine function of the urinary bladder of storing urine and voiding becomes compromised. In addition to functional deficiencies, these pathologies are often accompanied by changes in bladder wall tissue morphology and mechanical properties. Our experimental studies have revealed that the bladder wall can undergo rapid remodeling post-SCI (figs.1,2) and exhibits complex biomechanical responses (fig.2B) [1,2,3,4]. These remodeling events will result in profound changes in bladder wall biomechanical behavior (fig.2) and ultimately organ function. The specific alterations in mechanical behavior and functional properties of bladder wall tissue and the underlying mechanisms are not well understood. A multi-phase structural constitutive model of the bladder wall is clearly needed to understand how changes in various tissue components produce observed changes in bladder function.

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