The efficacy of botulinum toxin A and sacral neuromodulation in the management of interstitial cystitis (IC)/bladder pain syndrome (BPS), what do we know? ICI-RS 2017 think thank, Bristol

2018 ◽  
Vol 37 (S4) ◽  
pp. S99-S107 ◽  
Author(s):  
Mohammad S. Rahnama'i ◽  
Tom Marcelissen ◽  
Apostolos Apostolidis ◽  
Nikolaus Veit-Rubin ◽  
Brigitte Schurch ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Interstitial Cystitis ◽  
Sacral Neuromodulation ◽  
Botulinum Toxin A ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Toxin A ◽  
Bladder Pain

642 INTRA-TRIGONAL INJECTION OF BOTULINUM TOXIN A IN PATIENTS WITH REFRACTORY BLADDER PAIN SYNDROME/INTERSTITIAL CYSTITIS: LONG TERM RESULTS

2010 ◽  
Vol 9 (2) ◽  
pp. 213
Author(s):  
R.M.C.A. Pinto ◽  
T.A. Lopes ◽  
A.S. Silva ◽  
Silva J.F. Alturas ◽  
C.P. Martins Da Silva ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Interstitial Cystitis ◽  
Botulinum Toxin A ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Long Term Results ◽  
Toxin A ◽  
Bladder Pain

scholarly journals Botulinum Toxin A for Bladder Pain Syndrome/Interstitial Cystitis

Toxins ◽  
2016 ◽  
Vol 8 (7) ◽  
pp. 201 ◽  
Author(s):  
Bin Chiu ◽  
Huai-Ching Tai ◽  
Shiu-Dong Chung ◽  
Lori Birder
Keyword(s):  
Botulinum Toxin ◽  
Interstitial Cystitis ◽  
Botulinum Toxin A ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Toxin A ◽  
Bladder Pain

Trigonal Injection of Botulinum Toxin A in Patients with Refractory Bladder Pain Syndrome/Interstitial Cystitis

2010 ◽  
Vol 58 (3) ◽  
pp. 360-365 ◽  
Author(s):  
Rui Pinto ◽  
Tiago Lopes ◽  
Bárbara Frias ◽  
André Silva ◽  
João Alturas Silva ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Interstitial Cystitis ◽  
Botulinum Toxin A ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Toxin A ◽  
Bladder Pain

scholarly journals Using Botulinum Toxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome—Possible Pathomechanisms and Practical Issues

Toxins ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 641 ◽  
Author(s):  
Jia-Fong Jhang
Keyword(s):  
Botulinum Toxin ◽  
Interstitial Cystitis ◽  
Standard Treatment ◽  
Botulinum Toxin A ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Placebo Control ◽  
Toxin A ◽  
Bladder Pain ◽  
Number Of Patients

Treatment for patients with interstitial cystitis/bladder pain syndrome (IC/BPS) is always challenging for urologists. The main mechanism of the botulinum toxin A (BoNT-A) is inhibition of muscle contraction, but the indirect sensory modulation and anti-inflammatory effect in the bladder also play important roles in treating patients with IC/BPS. Although current guidelines consider BoNT-A injection to be a standard treatment, some practical issues remain debatable. Most clinical evidence of this treatment comes from retrospective uncontrolled studies, and only two randomized placebo-control studies with limited patient numbers have been published. Although 100 U BoNT-A is effective for most patients with IC/BPS, the potential efficacy of 200 U BoNT-A has not been evaluated. Both trigone and diffuse body BoNT-A injections are effective and safe for IC/BPS, although comparison studies are lacking. For IC/BPS patients with Hunner’s lesion, the efficacy of BoNT-A injection remains controversial. Most patients with IC/BPS experience symptomatic relapse at six to nine months after a BoNT-A injection, although repeated injections exhibit a persistent therapeutic effect in long-term follow-up. Further randomized placebo-controlled studies with a larger number of patients are needed to support BoNT-A as standard treatment for patients with IC/BPS.

MP29-18 BOTULINUM TOXIN A BLADDER INJECTION IN THE TREATMENT OF BLADDER PAIN SYNDROME/IC: TRYING TO STANDARDIZE THE TECHNIQUE

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Cristina Gutiérrez ◽  
Carlos Errando ◽  
Nicolas Nervo ◽  
Pedro Araño ◽  
Humberto Villavicencio
Keyword(s):  
Botulinum Toxin ◽  
Botulinum Toxin A ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Toxin A ◽  
Bladder Pain

INTRA-TRIGONAL INJECTION OF BOTULINUM TOXIN A IN PATIENTS WITH BLADDER PAIN SYNDROME - RESULTS AT 9-MONTHS FOLLOW-UP

2009 ◽  
Vol 181 (4S) ◽  
pp. 20-20 ◽  
Author(s):  
Rui A Pinto ◽  
André Silva ◽  
Tiago Lopes ◽  
João F Silva ◽  
Carlos M Silva ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Botulinum Toxin A ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Toxin A ◽  
Bladder Pain
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