Effect of short- and long-term sildenafil treatment on erectile dysfunction in rats with partial bladder outlet obstruction

2014 ◽  
Vol 35 (1) ◽  
pp. 108-114 ◽  
Author(s):  
Serap Gur ◽  
Buket Yurdaarmagan ◽  
Nur Bayatli ◽  
Suresh C. Sikka
2007 ◽  
Vol 26 (7) ◽  
pp. 1043-1049 ◽  
Author(s):  
Ahmet Guven ◽  
Bulent Onal ◽  
Carmin Kalorin ◽  
Catherine Whitbeck ◽  
Paul Chichester ◽  
...  

2008 ◽  
Vol 102 (11) ◽  
pp. 1651-1657 ◽  
Author(s):  
Serap Gur ◽  
Suresh C. Sikka ◽  
Surabhi Chandra ◽  
Padma Sandeep Koka ◽  
Krishna C. Agrawal ◽  
...  

2021 ◽  
Vol 320 (5) ◽  
pp. F838-F858
Author(s):  
Lipeng Chen ◽  
Linchen Lv ◽  
Lekai Zhang ◽  
Zhengdong Gao ◽  
Yaxiao Liu ◽  
...  

The present study in a rat model showed that oral administration of metformin alleviated inflammation following partial bladder outlet obstruction in the early phase and ameliorated bladder fibrosis as well as bladder dysfunction by long-term treatment. Our study indicated that metformin is a potential drug to inhibit bladder remodeling and alleviate bladder dysfunction. Clinical trials are needed to validate the effect of metformin on the bladder dysfunction and bladder fibrosis in the future.


2005 ◽  
Vol 173 (4S) ◽  
pp. 394-394
Author(s):  
Martha A. Hass ◽  
Robert M. Levin ◽  
William Connors ◽  
Alma Birnboim

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