scholarly journals Gastrocnemius muscle architecture and achilles tendon properties influence walking distance in claudicants with peripheral arterial disease

2016 ◽  
Vol 53 (5) ◽  
pp. 733-741 ◽  
Author(s):  
Stephanie Louise King ◽  
Natalie Vanicek ◽  
Thomas Daniel O'brien
Keyword(s):  
Peripheral Arterial Disease ◽  
Achilles Tendon ◽  
Gastrocnemius Muscle ◽  
Arterial Disease ◽  
Muscle Architecture ◽  
Walking Distance ◽  
Peripheral Arterial ◽  
Tendon Properties

scholarly journals Heat therapy vs. supervised exercise therapy for peripheral arterial disease: a 12-wk randomized, controlled trial

2019 ◽  
Vol 316 (6) ◽  
pp. H1495-H1506 ◽  
Author(s):  
Ashley P. Akerman ◽  
Kate N. Thomas ◽  
Andre M. van Rij ◽  
E. Dianne Body ◽  
Mesfer Alfadhel ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Peripheral Arterial Disease ◽  
Water Immersion ◽  
Ankle Brachial Index ◽  
Arterial Disease ◽  
Hot Water ◽  
Walking Distance ◽  
Supervised Exercise ◽  
Heat Therapy ◽  
Peripheral Arterial

Peripheral arterial disease (PAD) is characterized by lower limb atherosclerosis impairing blood supply and causing walking-induced leg pain or claudication. Adherence to traditional exercise training programs is poor due to these symptoms despite exercise being a mainstay of conservative treatment. Heat therapy improves many cardiovascular health outcomes, so this study tested if this was a viable alternative cardiovascular therapy for PAD patients. Volunteers with PAD were randomized to 12 wk of heat ( n = 11; mean age 76 ± 8 yr, BMI 28.7 ± 3.5 kg/m2, 4 females) or exercise ( n = 11; 74 ± 10 yr, 28.5 ± 6.8 kg/m2, 3 females). Heat involved spa bathing at ∼39°C, 3–5 days/wk for ≤30 min, followed by ≤30 min of callisthenics. Exercise involved ≤90 min of supervised walking and gym-based exercise, 1–2 days/wk. Following the interventions, total walking distance during a 6-min walk test increased (from ∼350 m) by 41 m (95% CI: [13, 69], P = 0.006) regardless of group, and pain-free walking distance increased (from ∼170 m) by 43 m ([22, 63], P < 0.001). Systolic blood pressure was reduced more following heat (−7 mmHg, [−4, −10], P < 0.001) than following exercise (−3 mmHg, [0, −6], P = 0.078), and diastolic and mean arterial pressure decreased by 4 mmHg in both groups ( P = 0.002). There were no significant changes in blood volume, ankle-brachial index, or measures of vascular health. There were no differences in the improvement in functional or blood pressure outcomes between heat and exercise in individuals with PAD. NEW & NOTEWORTHY Heat therapy via hot-water immersion and supervised exercise both improved walking distance and resting blood pressure in peripheral arterial disease (PAD) patients over 12 wk. Adherence to heat therapy was excellent, and the heat intervention was well tolerated. The results of the current study indicate that heat therapy can improve functional ability and has potential as an effective cardiovascular conditioning tool for individuals with PAD. Listen to this article's corresponding podcast at https://ajpheart.podbean.com/e/heat-therapy-vs-exercise-in-peripheral-arterial-disease/ .

scholarly journals Symptoms of Intermittent Claudication and Decreased Walking Tolerance in Patients Suffering from Peripheral Arterial Disease can be Improved with a Simple Herbal Supplement

2020 ◽  
pp. 1-5
Author(s):  
Ping-Chung Leung ◽  
Chook Ping ◽  
Kwok Chi Yui Timothy ◽  
Ping-Chung Leung ◽  
Woo Kam Sang ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Placebo Group ◽  
Treatment Group ◽  
Peripheral Arterial Disease ◽  
Cardiovascular Health ◽  
Arterial Disease ◽  
Walking Distance ◽  
Care Practice ◽  
Pragmatic Clinical Trials ◽  
Peripheral Arterial

Introduction: We have developed an innovative herbal formula containing two herbs of popular use for the supplementation of cardiovascular health. Three clinical trials, viz. on patients with coronary arterial obstruction, hypertension, and post-menopausal borderline hyperlipidaemia, have been done, all showing promising results detected in ultrasonography as diminished intima media thickness (IMT), a surrogate marker recommended for clinical trials related to cardiovascular health. 49+49 patients with known peripheral arterial disease (PAD) were treated with twin formula or placebo group for 24 weeks. Assessment using ultrasonography showed thinning down of the carotid intima (2.67%) only in the treatment group. Maximal walking distance also increased by 21.8% in the treatment group compared with 7.2% in the placebo group (p=0.499). Discussion: The positive results in the PAD study as well as in the other studies done previously demonstrated the effectiveness of the twin formula in the maintenance of cardiovascular health. It is safe and offers direct protection of the internal environment of the artery while at the same time carries the multiple roles of anti-inflammation, anti-oxygenation and anti-fibrosis, as were shown in in vitro and animal bioactivity studies. Conclusion and Outlook: The twin formula offers a good example of evidence-based medicinal supplements with specific functions. Its developmental process also offers a more comprehensive way to test traditional wisdom and practice through pragmatic clinical trials in the attempt to properly introduce it to modern health care practice.

scholarly journals Supervised Cycling Training Improves Erythrocyte Rheology in Individuals With Peripheral Arterial Disease

2022 ◽  
Vol 12 ◽  
Author(s):  
Chih-Chin Hsu ◽  
Yu-Ting Lin ◽  
Tieh-Cheng Fu ◽  
Shu-Chun Huang ◽  
Cheng-Hsien Lin ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Aerobic Capacity ◽  
Short Form ◽  
Ankle Brachial Index ◽  
Arterial Disease ◽  
Walking Distance ◽  
Supervised Exercise ◽  
Sf 36 ◽  
Peripheral Arterial ◽  
Cycling Training

Peripheral arterial disease (PAD) results in insufficient flow to lower extremities. Aerobic exercise provides health benefits for individuals with PAD, but basic science behind it is still debated. Twenty-one PAD patients aged about 70 years with female/male as 7/14 were recruited. Among them, 11 were randomized to have supervised cycling training (SCT) and 10 to receive general healthcare (GHC) as controls. SCT participants completed 36 sessions of SCT at the first ventilation threshold within 12 weeks and the controls received GHC for 12 weeks. Ankle-brachial index (ABI), 6-min walk test (6MWT), peak oxygen consumption (V˙O2peak), minute ventilation (V˙E), minute carbon dioxide production (V˙CO2), erythrocyte rheology, including the maximal elongation index (EImax) and shear stress at 50% of maximal elongation (SS1/2), and the Short Form-36 (SF-36) questionnaire for quality of life (QoL) were assessed before and 12 weeks after initial visit. SCT significantly decreased the SS1/2 as well as SS1/2 to EImax ratio (SS1/2/EImax) and increased the erythrocyte osmolality in the hypertonic region as well as the area under EI-osmolality curve. The supervised exercise-induced improvement of erythrocyte deformability could contribute to the increased peripheral tissue O2 delivery and was possibly related with increased V˙O2peak. The physiological benefit was associated with significantly increased ABI, 6-min walking distance, cardiorespiratory fitness, and SF-36 score. However, no significant changes in aerobic capacity and erythrocyte rheological properties were observed after 12-week of GHC. In conclusion, SCT improves aerobic capacity by enhancing erythrocyte membrane deformability and consequently promotes QoL in PAD patients.

Treadmill test is limited in elderly patients with peripheral arterial disease

VASA ◽  
2010 ◽  
Vol 39 (3) ◽  
pp. 237-241 ◽  
Author(s):  
Wolosker ◽  
Ritti-Dias ◽  
Câmara ◽  
Garcia ◽  
Jacob-Filho ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Elderly Patients ◽  
Arterial Disease ◽  
Exercise Stress ◽  
Walking Distance ◽  
Stress Tests ◽  
Treadmill Test ◽  
Peripheral Arterial ◽  
Walking Time

Background: To describe the applicability and the performance of the treadmill test in elderly patients with peripheral arterial disease (PAD) and without PAD (non-PAD). Patients and methods: Fifty consecutive PAD and non-PAD elderly patients performed a progressive treadmill test. The proportion of patients who were unable to perform the test and the maximal walking distance were obtained. Results: The proportion of patients who were unable to perform the treadmill test was similar between PAD (16.6 %) and non-PAD patients (12.5 %), P = .57. Maximal walking time for patients who performed the treadmill test was not different between PAD (232 ± 218 s) and non-PAD patients (308 ± 289 s), P = .37. Conclusions: The treadmill test is limited in almost 20 % of elderly patients with PAD and non-PAD. These results highlight the need for other forms of exercise stress tests in order to assess the peripheral limitation of patients with PAD.

Sign in / Sign up

Export Citation Format

Share Document