Influence of intrinsic noise generated by a thermotesting device on thermal sensory detection and thermal pain detection thresholds

2009 ◽  
Vol 40 (2) ◽  
pp. 257-263 ◽  
Author(s):  
G. Pavlaković ◽  
K. Züchner ◽  
A. Zapf ◽  
C.G. Bachmann ◽  
B.M. Graf ◽  
...  
2001 ◽  
Vol 24 (10) ◽  
pp. 1339-1345 ◽  
Author(s):  
Petra M. Meier ◽  
Charles B. Berde ◽  
James DiCanzio ◽  
David Zurakowski ◽  
Navil F. Sethna

2007 ◽  
Vol 107 (2) ◽  
pp. 298-304 ◽  
Author(s):  
Eske K. Aasvang ◽  
Bo Møhl ◽  
Henrik Kehlet

Background Sexual dysfunction due to ejaculatory and genital pain after groin hernia surgery may occur in approximately 2.5% of patients. However, the specific psychosexological and neurophysiologic characteristics have not been described, thereby precluding assessment of pathogenic mechanisms and treatment strategies. Methods Ten patients with severe pain-related sexual dysfunction and ejaculatory pain were assessed in detail by quantitative sensory testing and interviewed by a psychologist specialized in evaluating sexual functional disorders and were compared with a control group of 20 patients with chronic pain after groin hernia repair but without sexual dysfunction, to identify sensory changes associated with ejaculatory pain. Results Quantitative sensory testing showed significantly higher thermal and mechanical detection thresholds and lowered mechanical pain detection thresholds in both groups compared with the nonpainful side. Pressure pain detection threshold and tolerance were significantly lower in the ejaculatory pain group compared with the control group. 'The maximum pain was specifically located at the external inguinal annulus in all ejaculatory pain patients, but not in controls. The psychosexual interview revealed no major psychosexual disturbances and concluded that the pain was of somatic origin. All patients with ejaculatory pain had experienced major negative life changes and deterioration in their overall quality of life and sexual function as a result of the hernia operation. Conclusions Postherniotomy ejaculatory pain and pain-related sexual dysfunction is a specific chronic pain state that may be caused by pathology involving the vas deferens and/or nerve damage. Therapeutic strategies should therefore include neuropathic pain treatment and/or surgical exploration.


2020 ◽  
Vol 10 (18) ◽  
pp. 6531
Author(s):  
Mizuho Sumitani ◽  
Michihiro Osumi ◽  
Hiroaki Abe ◽  
Kenji Azuma ◽  
Rikuhei Tsuchida ◽  
...  

People perceive the mind in two dimensions: intellectual and affective. Advances in artificial intelligence enable people to perceive the intellectual mind of a robot through their semantic interactions. Conversely, it has been still controversial whether a robot has an affective mind of its own without any intellectual actions or semantic interactions. We investigated pain experiences when observing three different facial expressions of a virtual agent modeling affective minds (i.e., painful, unhappy, and neutral). The cold pain detection threshold of 19 healthy subjects was measured as they watched a black screen, then changes in their cold pain detection thresholds were evaluated as they watched the facial expressions. Subjects were asked to rate the pain intensity from the respective facial expressions. Changes of cold pain detection thresholds were compared and adjusted by the respective pain intensities. Only when watching the painful expression of a virtual agent did, the cold pain detection threshold increase significantly. By directly evaluating intuitive pain responses when observing facial expressions of a virtual agent, we found that we ‘share’ empathic neural responses, which can be intuitively emerge, according to observed pain intensity with a robot (a virtual agent).


1994 ◽  
Vol 2 (1) ◽  
pp. 95-106 ◽  
Author(s):  
Kenneth A. Perkins ◽  
James E. Grobe ◽  
Richard L. Stiller ◽  
Annette Scierka ◽  
Jennifer Goettler ◽  
...  
Keyword(s):  

Neurology ◽  
1993 ◽  
Vol 43 (8) ◽  
pp. 1500-1500 ◽  
Author(s):  
P. J. Dyck ◽  
I. Zimmerman ◽  
D. A. Gillen ◽  
D. Johnson ◽  
J. L. Karnes ◽  
...  

Gut ◽  
1997 ◽  
Vol 41 (6) ◽  
pp. 753-757 ◽  
Author(s):  
A M Drewes ◽  
L Arendt-Nielsen ◽  
J H Jensen ◽  
J B Hansen ◽  
H B Krarup ◽  
...  

Background—Abdominal pain is often variable in intensity and difficult to characterise due to its referred pain pattern. Clinical pain is furthermore confounded by various emotional and cognitive factors.Aims—To develop and apply an experimental model to induce localised gastric pain.Subjects—Twelve healthy male volunteers.Methods—Stimulating electrodes were mounted on a biopsy forceps and electric stimuli were delivered during gastroscopy. Single, five repeated, and continuous stimuli were given at four locations in the stomach. Pain detection thresholds and pain intensities were assessed together with localisation of the referred pain area.Results—Pain detection thresholds were higher in the prepyloric region compared with those obtained at the lesser and greater curvature. Increasing stimulus intensity resulted in augmented pain perception and repeated stimuli elicited pain at a lower stimulus intensity than single stimuli. Continuous stimuli evoked constant (33%), increasing (33%), or decreasing (33%) pain. The localisation of referred pain varied considerably in the subjects.Conclusions—The model seems relevant to study basic pain mechanisms elicited by localised stimuli in the stomach. The experimental data support the premise that a gastric focus should always be suspected in patients referred with different kinds of abdominal pain.


Cephalalgia ◽  
1996 ◽  
Vol 16 (3) ◽  
pp. 175-182 ◽  
Author(s):  
R Jensen ◽  
J Olesen

To elucidate possible myofascial mechanisms of tension-type headache, the effect of 30 min of sustained tooth clenching (10% of maximal EMG-signal) was studied in 58 patients with tension-type headache and in 30 age- and sex-matched controls. Pericranial tenderness, mechanical and thermal pain detection and tolerance thresholds and FMG levels were recorded before and after the clenching procedure. Within 24 h, 69% of patients and 17% of controls developed a tension-type headache. Shortly after clenching, tenderness was increased in the group who subsequently developed headache, whereas tenderness was stable in the group of patients who remained headache free. Mechanical pain thresholds evaluated by pressure algometry remained unchanged in the group which developed headache, whereas thresholds increased in the group which did not develop headache Thermal pain detection and tolerance thresholds remained unchanged in both groups. These findings indicate that, though there may be several different mechanisms of tension-type headache, one of them is sustained muscle contraction. A peripheral mechanism of tension-type headache is therefore possible, whereas a secondary segmental central sensitization seems to be involved in subjects with frequent, tension-type headache. Finally, the increase in pressure pain thresholds in patients who did not develop headache suggested that clenching activated their antinociceptive system, whereas those developing headache were, unable to do so.


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