Assessment of the reliability of central and peripheral fatigue after sustained maximal voluntary contraction of the quadriceps muscle

2007 ◽  
Vol 35 (4) ◽  
pp. 486-495 ◽  
Author(s):  
Nicolas Place ◽  
Nicola A. Maffiuletti ◽  
Alain Martin ◽  
Romuald Lepers
Keyword(s):  
Maximal Voluntary Contraction ◽  
Quadriceps Muscle ◽  
Voluntary Contraction ◽  
Peripheral Fatigue

Fatigued patients with multiple sclerosis have impaired central muscle activation

2009 ◽  
Vol 15 (7) ◽  
pp. 818-827 ◽  
Author(s):  
AK Andreasen ◽  
J Jakobsen ◽  
T Petersen ◽  
H Andersen
Keyword(s):  
Multiple Sclerosis ◽  
Maximal Voluntary Contraction ◽  
Muscle Activation ◽  
Quadriceps Muscle ◽  
Voluntary Contraction ◽  
Central Activation ◽  
Motor Activation ◽  
Fatigue Severity ◽  
The Right ◽  
Peripheral Activation

Background The pathogenesis of fatigue in multiple sclerosis (MS) is poorly understood. Objective To elucidate the role of central motor activation we hypothesized that patients with primary fatigue have impaired central motor function and increased fatigability as compared to secondary fatigued and non-fatigued patients. Methods Sixty patients with relapsing remitting MS and an Expanded Disability Status Scale score ≤ 3.5 were recruited and grouped as fatigued (Fatigue Severity Scale (FSS) ≥ 5.0) or non-fatigued (FSS ≤ 4.0). Nineteen patients were primary fatigued, 20 secondary fatigued and 21 non-fatigued. Maximal voluntary contraction, central activation and peripheral activation were determined by percutaneous twitch interpolation of the right quadriceps muscle. Results Maximal voluntary contraction was similar between groups but did relate to scores of fatigue. Peripheral activation was similar in all groups. Central activation was impaired in both groups of fatigued patients compared to non-fatigued patients being 0.96(0.05) in primary fatigued and 0.96(0.04) in secondary fatigued versus 0.99(0.1) in non-fatigued patients. The impairment of central motor activation was related to degree of fatigue in all patients. During fatiguing exercise there was a similar loss of strength, without any time differences between the three groups. Conclusion We conclude that impaired central motor activation is involved in MS-fatigue.

Central and Peripheral Fatigue in Sustained Maximum Voluntary Contractions of Human Quadriceps Muscle

1978 ◽  
Vol 54 (6) ◽  
pp. 609-614 ◽  
Author(s):  
B. Bigland-Ritchie ◽  
D. A. Jones ◽  
G. P. Hosking ◽  
R. H. T. Edwards
Keyword(s):  
Maximum Voluntary Contraction ◽  
Central Fatigue ◽  
Quadriceps Muscle ◽  
Surface Emg ◽  
Voluntary Contraction ◽  
Peripheral Fatigue ◽  
Emg Activity ◽  
Limiting Factor ◽  
Extra Effort ◽  
Voluntary Contractions

1. The fatigue of force that occurs during the first 60 s of a maximum voluntary contraction of the human quadriceps has been examined by comparing the voluntary force with that obtained by brief tetanic stimulation at 50 Hz in nine healthy subjects. In three subjects the voluntary force declined in parallel with the tetanic force whereas in the remainder it fell more rapidly, suggesting that central fatigue was present. 2. For those subjects who showed little or no central fatigue, surface electromyograph (EMG) activity remained approximately constant while the force declined by about 60%. In the others, EMG activity and force declined in parallel but when an extra effort was made the subjects could briefly increase their force and this was accompanied by a proportionately greater increase in EMG activity (generally up to the original value). 3. It is concluded that in sustained maximum voluntary contractions of the quadriceps (a) central fatigue may account for an appreciable proportion of the force loss, (b) surface EMG recordings provide no evidence that neuromuscular junction failure is the limiting factor determining the loss of force in this muscle.

scholarly journals Mechanisms of neuromuscular fatigue and recovery in unilateral versus bilateral maximal voluntary contractions

2020 ◽  
Vol 128 (4) ◽  
pp. 785-794
Author(s):  
Jérôme Koral ◽  
Dustin J. Oranchuk ◽  
James G. Wrightson ◽  
Rosie Twomey ◽  
Guillaume Y. Millet
Keyword(s):  
Peripheral Nerve ◽  
Nerve Stimulation ◽  
Maximal Voluntary Contraction ◽  
Neuromuscular Function ◽  
Voluntary Contraction ◽  
Submaximal Exercise ◽  
Neuromuscular Fatigue ◽  
Corticospinal Excitability ◽  
Peripheral Fatigue ◽  
Knee Extensors

The aim of this study was to investigate differences in neuromuscular function and corticospinal excitability in response to sustained unilateral (UNIL) and bilateral (BIL) isometric maximal voluntary contraction (IMVC) of the knee extensors. Eleven men performed a 1-min sustained IMVC of the knee extensors with one or both legs. Central and peripheral measures of neuromuscular function and corticospinal excitability were assessed via surface electromyography (EMG), peripheral nerve stimulation, and transcranial magnetic stimulation before, immediately after, and during recovery from IMVC. IMVC force and root-mean-squared EMG decreased during the fatiguing 1-min IMVC, with a larger decrease in EMG during BIL. All neuromuscular function indexes decreased significantly after the IMVC ( P < 0.005), but the magnitude of these decreases did not differ between conditions. Changes in corticospinal excitability (motor evoked potential) and inhibition (silent period) did not differ between conditions. In contrast to previous studies utilizing submaximal exercise, no more peripheral fatigue was found after UNIL vs. BIL conditions, even though central drive was lower after BIL 1-min IMVC. Corticospinal excitability and inhibition were not found to be different between UNIL and BIL conditions, in line with maximal voluntary activation. NEW & NOTEWORTHY The present experiment used peripheral nerve stimulation and transcranial magnetic stimulations during a sustained isometric maximal voluntary contraction to investigate the influence of muscle mass on neuromuscular fatigue. Contrary to previous studies that used submaximal exercise, peripheral fatigue was not found to be greater in unilateral vs. bilateral knee extensions even though central drive was lower during bilateral contractions. Corticospinal excitability and inhibition were not found to be different between unilateral and bilateral conditions.

scholarly journals Feasibility of an Isometric Maximal Voluntary Contraction Test in Hematological Cancer Patients during Thrombocytopenia

2013 ◽  
Vol 2013 ◽  
pp. 1-6
Author(s):  
Philipp Zimmer ◽  
Freerk T. Baumann ◽  
Janis Ebel ◽  
Eva Maria Zopf ◽  
Wilhelm Bloch ◽  
...  
Keyword(s):  
Resistance Training ◽  
Maximal Voluntary Contraction ◽  
Brief Pain Inventory ◽  
Quadriceps Muscle ◽  
Voluntary Contraction ◽  
Resistance Training Program ◽  
Repetition Maximum ◽  
Maximum Test ◽  
Oncological Patients ◽  
The One

Introduction. Resistance training is rarely offered to hemato-oncological patients in the daily clinical routine due to its potential harmful impact on the cardiovascular system and the long periods of thrombocytopenia experienced by these patients. Therefore, it is important to determine a valid assessment to define and control resistance training. In this study, the feasibility of a maximal voluntary contraction (MVC) test was investigated in hemato-oncological patients. This inexpensive assessment may be a practicable alternative to the one repetition maximum test which is currently described as the gold standard.Methods. 29 hemato-oncological patients with platelet counts between 30000/μL and 70000/μL were recruited for this pilot study. Complications like petechial bleedings, muscle convulsion, and pain were assessed using the Brief Pain Inventory before and 48 hours after the MVC test, which was performed unidirectionally for the quadriceps muscle.Results. We did not detect any statistically significant test-related exacerbations or pain development.Discussion. MVC testing seems to be a feasible method to control a resistance training program in hemato-oncological patients. Further studies need to extend their methods and, for example, compare the MVC test with the one repetition maximum test.

Effects of two nights of sleep deprivation on executive function and central and peripheral fatigue during maximal voluntary contraction lasting 60s

2021 ◽  
Vol 229 ◽  
pp. 113226
Author(s):  
Albertas Skurvydas ◽  
Diana Kazlauskaite ◽  
Laura Zlibinaite ◽  
Agne Cekanauskaite ◽  
Dovile Valanciene ◽  
...  
Keyword(s):  
Executive Function ◽  
Sleep Deprivation ◽  
Maximal Voluntary Contraction ◽  
Voluntary Contraction ◽  
Peripheral Fatigue

Neuromuscular Fatigue in Individuals With Intellectual Disability: Comparison Between Sedentary Individuals and Athletes

Motor Control ◽  
2021 ◽  
Vol 25 (2) ◽  
pp. 264-282
Author(s):  
Rihab Borji ◽  
Firas Zghal ◽  
Nidhal Zarrouk ◽  
Sonia Sahli ◽  
Haithem Rebai
Keyword(s):  
Intellectual Disability ◽  
Recovery Period ◽  
Voluntary Contraction ◽  
Neuromuscular Fatigue ◽  
Voluntary Activation ◽  
Peripheral Fatigue ◽  
Typical Development ◽  
Activation Level ◽  
Voluntary Activation Level ◽  
Voluntary Contractions

The authors explored neuromuscular fatigue in athletes with intellectual disability (AID) compared with sedentary individuals with intellectual disability (SID) and individuals with typical development. Force, voluntary activation level, potentiated resting twitch, and electromyography signals were assessed during isometric maximal voluntary contractions performed before and immediately after an isometric submaximal exhaustive contraction (15% isometric maximal voluntary contractions) and during recovery period. AID presented shorter time to task failure than SID (p < .05). The three groups presented similar isometric maximal voluntary contraction decline and recovery kinetic. Both groups with intellectual disability presented higher voluntary activation level and root mean square normalized to peak-to-peak M-wave amplitude declines (p < .05) compared with individuals with typical development. These declines were more pronounced in SID (p < .05) than in AID. The AID recovered their initial voluntary activation level later than controls, whereas SID did not. SID presented lower potentiated resting twitch decline compared with AID and controls with faster recovery (p < .05). AID presented attenuated central fatigue and accentuated peripheral fatigue compared with their sedentary counterparts, suggesting a neuromuscular profile close to that of individuals with typical development.

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