Lack of human muscle architectural adaptation after short-term strength training

2007 ◽  
Vol 35 (1) ◽  
pp. 78-86 ◽  
Author(s):  
Anthony J. Blazevich ◽  
Nicholas D. Gill ◽  
Nathan Deans ◽  
Shi Zhou
Keyword(s):  
Strength Training ◽  
Human Muscle ◽  
Term Strength ◽  
Short Term ◽  
Short Term Strength

scholarly journals Strength exercise reduces hepatic pyruvate carboxylase and gluconeogenesis in DIO mice

2020 ◽  
Vol 247 (2) ◽  
pp. 127-138
Author(s):  
Rodrigo Martins Pereira ◽  
Kellen Cristina da Cruz Rodrigues ◽  
Marcella Ramos Sant’Ana ◽  
Guilherme Francisco Peruca ◽  
Ana Paula Morelli ◽  
...  
Keyword(s):  
Strength Training ◽  
Pyruvate Carboxylase ◽  
Hepatic Glucose Production ◽  
Glucose Production ◽  
Mrna Levels ◽  
Strength Exercise ◽  
Term Strength ◽  
Short Term ◽  
Hepatic Glucose ◽  
Short Term Strength

Obesity is linked to a reduction in the control of hepatic glucose production, which is the primary mechanism related to fasting hyperglycemia and the development of type 2 diabetes mellitus (T2DM). The main system involved in hepatic gluconeogenesis synthesis is controlled by pyruvate carboxylase (PC), which increases in obesity conditions. Recently, we showed that short-term strength training is an important tool against obesity-induced hyperglycemia. As aerobic exercise can reduce the hepatic PC content of obese animals, we hypothesized that strength exercise can also decrease this gluconeogenic enzyme. Therefore, this study investigated whether the metabolic benefits promoted by short-term strength training are related to changes in hepatic PC content. Swiss mice were divided into three groups: lean control (Ctl), obese sedentary (ObS), and obese short-term strength training (STST). The STST protocol was performed through one session/day for 15 days. The obese exercised animals had reduced hyperglycemia and insulin resistance. These results were related to better control of hepatic glucose production and hepatic insulin sensitivity. Our bioinformatics analysis showed that hepatic PC mRNA levels have positive correlations with glucose levels and adiposity, and negative correlations with locomotor activity and muscle mass. We also found that hepatic mRNA levels are related to lipogenic markers in the liver. Finally, we observed that the obese animals had an increased hepatic PC level; however, STST was efficient in reducing its amount. In conclusion, we provide insights into new biomolecular mechanisms by showing how STST is an efficient tool against obesity-related hyperglycemia and T2DM, even without body weight changes.

scholarly journals Short-term strength training reduces gluconeogenesis and NAFLD in obese mice

2019 ◽  
Vol 241 (1) ◽  
pp. 59-70 ◽  
Author(s):  
Rodrigo Martins Pereira ◽  
Kellen Cristina da Cruz Rodrigues ◽  
Chadi Pellegrini Anaruma ◽  
Marcella Ramos Sant’Ana ◽  
Thaís Dantis Pereira de Campos ◽  
...  
Keyword(s):  
Weight Loss ◽  
Insulin Sensitivity ◽  
Strength Training ◽  
Term Strength ◽  
Obese Mice ◽  
Short Term ◽  
Fat Accumulation ◽  
Hepatic Insulin Sensitivity ◽  
Short Term Strength ◽  
Hepatic Fat

Non-alcoholic fatty liver disease (NAFLD) has a positive correlation with obesity, insulin resistance and type 2 diabetes mellitus (T2D). The aerobic training is an important tool in combating NAFLD. However, no studies have demonstrated the molecular effects of short-term strength training on the accumulation of hepatic fat in obese mice. This study aimed to investigate the effects of short-term strength training on the mechanisms of oxidation and lipid synthesis in the liver of obese mice. The short duration protocol was used to avoid changing the amount of adipose tissue. Swiss mice were separated into three groups: lean control (CTL), sedentary obese (OB) and strength training obese (STO). The obese groups were fed a high-fat diet (HFD) and the STO group performed the strength training protocol 1 session/day for 15 days. The short-term strength training reduced hepatic fat accumulation, increasing hepatic insulin sensitivity and controlling hepatic glucose production. The obese animals increased the mRNA of lipogenic genes Fasn and Scd1 and reduced the oxidative genes Cpt1a and Ppara. On the other hand, the STO group presented the opposite results. Finally, the obese animals presented higher levels of lipogenic proteins (ACC and FAS) and proinflammatory cytokines (TNF-α and IL-1β), but the short-term strength training was efficient in reducing this condition, regardless of body weight loss. In conclusion, there was a reduction of obesity-related hepatic lipogenesis and inflammation after short-term strength training, independent of weight loss, leading to improvements in hepatic insulin sensitivity and glycemic homeostasis in obese mice. Key points: (1) Short-term strength training (STST) reduced fat accumulation and inflammation in the liver; (2) Hepatic insulin sensitivity and HPG control were increased with STST; (3) The content and activity of ACC and content of FAS were reduced with STST; (4) STST improved hepatic fat accumulation and glycemic homeostasis; (5) STST effects were observed independently of body weight change.

scholarly journals Effects of single vs. multiple-set short-term strength training in elderly women

AGE ◽  
2014 ◽  
Vol 36 (6) ◽  
Author(s):  
Regis Radaelli ◽  
Eurico N. Wilhelm ◽  
Cíntia E. Botton ◽  
Anderson Rech ◽  
Martim Bottaro ◽  
...  
Keyword(s):  
Strength Training ◽  
Elderly Women ◽  
Term Strength ◽  
Short Term ◽  
Short Term Strength

Effects of Short-Term Strength Training on Maximal Velocity Parameters and Rate of Muscle Activation

2016 ◽  
Vol 48 ◽  
pp. 476
Author(s):  
Cameron S. Mackey ◽  
Garrett M. Hester ◽  
Zachary K. Pope ◽  
Frank M. Benik ◽  
Ryan J. Colquhoun ◽  
...  
Keyword(s):  
Strength Training ◽  
Muscle Activation ◽  
Maximal Velocity ◽  
Term Strength ◽  
Short Term ◽  
Short Term Strength

Identification Of Proteins Of Human Serum And Skeletal Muscle By Short-term Strength Training In Elite Korean Speed Skaters

2011 ◽  
Vol 43 (Suppl 1) ◽  
pp. 304
Author(s):  
Ester Chae ◽  
Hee Jeong Son ◽  
Hyo Jeong Kim ◽  
Joon Yong Cho ◽  
Yoon Man Kim ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Strength Training ◽  
Human Serum ◽  
Term Strength ◽  
Short Term ◽  
Short Term Strength

Short-Term Strength Training Does Not Alter Skeletal Muscle Capillarization In Young Or Older Women

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S54
Author(s):  
Gregory Martel ◽  
Briana Aiken ◽  
Michelle Brill ◽  
Stephen M. Roth ◽  
Ben F. Hurley ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Strength Training ◽  
Older Women ◽  
Term Strength ◽  
Short Term ◽  
Short Term Strength
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