Conduction velocity distribution in neurologically well-recovered but fatigued Guillain–Barré syndrome patients

2006 ◽  
Vol 33 (2) ◽  
pp. 177-182 ◽  
Author(s):  
Marcel P. J. Garssen ◽  
Joleen H. Blok ◽  
Pieter A. van Doorn ◽  
Gerhard H. Visser
Keyword(s):  
Velocity Distribution ◽  
Conduction Velocity ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Conduction Velocity Distribution ◽  
Guillain Barré

scholarly journals Neurophysiology of Guillain-Barré syndrome in children

2018 ◽  
Vol 9 (4) ◽  
pp. 50-57
Author(s):  
Vladislav B. Voitenkov ◽  
Natalia V. Skripchenko ◽  
Andrey V. Klimkin ◽  
Stepan G. Grigoriyev
Keyword(s):  
Action Potential ◽  
Median Nerve ◽  
Conduction Velocity ◽  
Peroneal Nerve ◽  
H Reflex ◽  
Guillain Barre Syndrome ◽  
Motor Conduction Velocity ◽  
Early Recovery ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Our aim was to evaluate sensitivity and specificity of conduction studies parameters for prognosis and differential diag nosis in children with acute motor axonal neuropathy (AMAN) & acute inflammatory demyelinating polyneuropathy (AIDP). Methods. 40 children were included: 20 healthy controls (7-14 years) and 20 patients (8-15 years) with AIDP or AMAN. All underwent conduction studies on 3-7 day since the clinical symptoms onset. We registered and evaluated motor conduction velocity, compound muscle action potential (CMAP) amplitude of nn. tibialis, peroneus, medianus, ulnaris; sensory conduction velocity & sensory nerve action potential (SNAP) amplitude for nn. medianus, suralis, peroneus superficialis, ulnaris, H-reflex threshold & latency, reactivity of neural conductivity (RNC) in short-term hand ischemia in acute phase (3-14 day since the disease onset) and in early recovery period (15-30 day since the symptoms onset). ROC-analysis was performed. Results. In 95% of the patients with Guillain-Barré syndrome H-reflex was absent. In first 10 days SNAP amplitude of median nerve >8.9 µV, peroneal nerve >3.6 µV, CMAP of peroneal nerve ≤0,4 µV with normal motor conduction velocity indicates AMAN presence. Motor axons of peripheral nerves in children in acute and recovery phase of AIDP are resistant towards ischemia. Prognostic criteria for long period of walk recovery (more than 30 days) in these patients are RNC on 10th minute of local ischemia ≤2.5%, ulnar nerve CMAP amplitude ≤1,1 mV and distal CMAP amplitude from median nerve ≤1.6 mV. Conclusions. Conduction studies may be implemented on all phases of Guillain-Barré syndrome in children for prognosis and differential diagnosis between its axonal and demyelinating forms. H-reflex absence in children in the first 5 days of acute polyneuropathy may serve as additional diagnostic criteria for Guillain-Barré syndrome. RNC parameters may be implemented for the prognosis of the walk period recovery duration.

scholarly journals Integrated Chinese and western medicine for acute guillain-barré syndrome treatment

2020 ◽  
Vol 11 (1) ◽  
pp. 38-47
Author(s):  
Liu Yang ◽  
Xiumin Zhao
Keyword(s):  
Conduction Velocity ◽  
Western Medicine ◽  
Nerve Conduction ◽  
Motor Nerve ◽  
Sensory Nerve ◽  
Guillain Barre Syndrome ◽  
Functional Score ◽  
Control Group ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

AbstractIntroductionGuillain-Barré syndrome (GBS) is a worldwide demyelinating polyradiculopathy and polyneuropathy. Currently, there is no specific drug for GBS, and established treatment is generally based on immune-modulating treatment with plasma exchange or intravenous immunoglobulin in combination with supportive care. This study aimed to investigate the efficiency of integrated Chinese and Western medicine for acute GBS treatment.MethodsWe enrolled 73 subjects, and randomly divided them into two groups: 35 cases in the traditional Chinese medicine (TCM) group, and 28 in the Control group. The Control group was treated with the common Western medicine for one month; and the TCM group was administrated with one month of common treatment combined with TCM medication.ResultsCompared to the controls, TCM significantly enhanced the treatment efficiency in symptom expression, including the TCM syndrome score, the activity of daily living score, Hughes functional score and sensory dysfunction assessment. The total effective rate of the TCM group was 94.29%, significantly better than controls (78.59%). Moreover, TCM provide better improvement in motor nerve conduction functions (distal motor latency and motor conduction velocity) and sensory nerve conduction functions (sensory conduction velocity and sensory nerve action potential) in median nerve, ulnar nerve, and common fibular nerve.ConclusionWhen combined with TCM administration, the GBS treatment could acquire better outcomes.

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