Identifying Patient-Reported Outcomes in Rheumatoid Arthritis: The Impact of Foot Symptoms on Self-Perceived Quality of Life

2012 ◽  
Vol 10 (2) ◽  
pp. 65-75 ◽  
Author(s):  
S. J. Otter ◽  
K. Lucas ◽  
K. Springett ◽  
A. Moore ◽  
K. Davies ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Patient Reported Outcomes ◽  
Perceived Quality ◽  
Perceived Quality Of Life ◽  
Patient Reported ◽  
The Impact

OP0160 The Impact of Rheumatoid Arthritis on Patient Reported Outcomes and Quality of Life Prior to Biologic Initiation

2015 ◽  
Vol 74 (Suppl 2) ◽  
pp. 129.2-130
Author(s):  
L.R. Harrold ◽  
K.K. Gandhi ◽  
C.J. Etzel ◽  
A. Nadkarni ◽  
K.C. Saunders ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Patient Reported Outcomes ◽  
Patient Reported ◽  
The Impact

P–499 infertility impact on perceived quality of life and sexual satisfaction in Spanish women with primary and secondary infertility

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
N Uriart. Beitia ◽  
P Guerr. Mora ◽  
M Penad. Abilleira
Keyword(s):  
Quality Of Life ◽  
Sexual Satisfaction ◽  
Measurement Instrument ◽  
Perceived Quality ◽  
Secondary Infertility ◽  
Infertile Women ◽  
Fertility Treatments ◽  
Perceived Quality Of Life ◽  
The Impact

Abstract Study question Are there any differences relating to the perceived quality of life (QoL) and sexual satisfaction among infertile women? Summary answer There were no differences between women who already had a baby and those who did not relating to the perceived QoL and sexual satisfaction. What is known already Infertility is a medical disease with a high social component with a 16% prevalence. There have been many investigations regarding to the physical part of the infertility but the sexual and marital satisfaction has not been as intensively investigated. The importance of the psychological counseling in fertility treatments has already been proven, but the significance of sexual satisfaction on individual’s perception on QoL has not been as deeply studied. Study design, size, duration A transversal descriptive study was done. 313 heterosexual married women with fertility problems were recruited in collaboration with the Spanish patient association “Red Nacional de Infértiles”. The Fertility quality of life tool (FertiQoL) was selected to measure the perceived QoL and the Index of Sexual Satisfaction (ISS) was chosen to study the degree of sexual satisfaction. The data collection was made between January and February 2020 and all the information was gathered online. Participants/materials, setting, methods 313 women filled the questionnaire which had 4 different modules: A sociodemographic module (sex, age, studies, time trying to conceive, moment of treatment and offspring), two modules for each measurement instrument and a last module in which they could write their personal experiences regarding to the infertility journey. ANOVA and t-Student statistical analyses were done to compare the different independent variables. To see if FertiQoL could explain the sexual satisfaction a regression analysis was made. Main results and the role of chance To achieve 95% power (α = 0.05) and an effect size of 0.25, a minimum sample size of 210 was needed and a sample of 313 women was recruited. There were no statistical differences between women with previous offspring and those who did not in neither of the FertiQoL subscales (Emotional: 7,4 ± 3,884 vs. 7,34 ± 4,235; Mind/Body: 9,65 ± 5,098 vs. 8,66 ± 4,979; Relational: 16,88 ± 4,807 vs. 16,3 ± 4,956; Social: 10,52 ± 5,02 vs. 10,1 ± 4,801; Tolerability: 5,91 ± 4,114 vs. 6,65 ± 3,357; Environment: 12,71 ± 5,02 vs. 11,42 ± 4,963) nor in the ISS questionnaire (47,48 ± 6,488 vs. 47,22 ± 7,35). Regarding to the power of the FertiQoL instrument and the perceived QoL to predict the sexual satisfaction, the regression model showed that the sexual satisfaction could be explained in 26,3% of the cases by the relational and mind/body subscales of the FertiQol tool. This model showed the inherent relationship between marital and personal wellbeing in order to obtain a better sexual satisfaction. Limitations, reasons for caution As the study had a transversal design, no cause-effect relationships could be done. It would be desirable to establish a longitudinal study in order to determine a more accurate relationship between the studied variables. Wider implications of the findings: This study showed that the impact of infertility in women with secondary infertility diagnose could be at least as high as in women with primary infertility diagnose. FertiQoL would be a reasonable instrument to estimate the sexual satisfaction of infertile women. Sexology should be part of the infertility counselling programs. Trial registration number Not applicable

scholarly journals Impact of Medium Cut-Off Dialyzers on Patient-Reported Outcomes: COREXH Registry

2020 ◽  
pp. 1-9
Author(s):  
Juan Carlos Alarcon ◽  
Alfonso Bunch ◽  
Freddy Ardila ◽  
Eduardo Zuñiga ◽  
Jasmin I. Vesga ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Kidney Disease ◽  
Repeated Measures ◽  
Patient Reported Outcomes ◽  
Short Form ◽  
High Flux ◽  
Middle Molecules ◽  
Patient Reported ◽  
The Impact

<b><i>Introduction:</i></b> A new generation of hemodialysis (HD) membranes called medium cut-off (MCO) membranes possesses enhanced capacities for middle molecule clearance, which have been associated with adverse outcomes in this population. These improvements could potentially positively impact patient-reported outcomes (PROs). <b><i>Objective:</i></b> The objective of this study was to evaluate the impact of MCO membranes on PROs in a cohort of HD patients in Colombia. <b><i>Methods:</i></b> This was a prospective, multicenter, observational cohort study of 992 patients from 12 renal clinics in Colombia who were switched from high-flux HD to MCO therapy and observed for 12 months. Changes in Kidney Disease Quality of Life 36-Item Short Form Survey (KDQoL-SF36) domains, Dialysis Symptom Index (DSI), and restless legs syndrome (RLS) 12 months after switching to MCO membranes were compared with time on high-flux membranes. Repeated measures of ANOVA were used to evaluate changes in KDQoL-SF36 scores; severity scoring was used to assess DSI changes over time; Cochran’s Q test was used to evaluate changes in frequency of diagnostic criteria of RLS. <b><i>Results:</i></b> During 12 months of follow-up, 3 of 5 KDQoL-SF36 domains improved compared with baseline: symptoms (<i>p</i> &#x3c; 0.0001), effects of kidney disease (<i>p</i> &#x3c; 0.0001), and burden of kidney disease (<i>p</i> &#x3c; 0.001). The proportion of patients diagnosed with RLS significantly decreased from 22.1% at baseline to 10% at 12 months (<i>p</i> &#x3c; 0.0001). No significant differences in the number of symptoms (DSI, <i>p =</i> 0.1) were observed, although their severity decreased (<i>p</i> = 0.009). <b><i>Conclusions:</i></b> In conventional HD patients, the expanded clearance of large middle molecules with MCO-HD membranes was associated with higher health-related quality of life scores and a decrease in the prevalence of RLS.

scholarly journals Gastrointestinal Symptoms of and Psychosocial Changes in Inflammatory Bowel Disease: A Nursing-Led Cross-Sectional Study of Patients in Clinical Remission

Medicina ◽  
2020 ◽  
Vol 56 (1) ◽  
pp. 45 ◽  
Author(s):  
Rosellina Margherita Mancina ◽  
Raffaele Pagnotta ◽  
Caterina Pagliuso ◽  
Vincenzo Albi ◽  
Daniela Bruno ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Patient Reported Outcomes ◽  
Gastrointestinal Symptoms ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Patient Reported ◽  
Inflammatory Bowel ◽  
The Impact

Background and Objectives: Nursing management in Inflammatory Bowel Disease (IBD) is focused on global patient care. Starting from basic knowledge of diagnostic and therapeutic management, nurses can assess the impact of IBD on patients’ quality of life not only at the physical level, but also at the psychological, social, and emotional levels. The aim of this study was to evaluate the impact of gastrointestinal symptoms on psychosocial changes in IBD patients in remission through nursing-led Patient-Reported Outcomes. Materials and Methods: We performed a cross-sectional study of 109 IBD patients in clinical and endoscopic remission. Specialist nurses invited patients to complete questionnaires on gastrointestinal symptoms and quality of life through the Patient-Reported Outcomes Measurement Information System (PROMIS). Results: We found that the gastrointestinal symptoms that the patients reported had a significant impact on the analyzed aspects of health. More specifically, belly pain, diarrhea, and bloating were associated with depressive symptoms (p < 0.001), anxiety (p < 0.001), fatigue (p < 0.001), and sleep disturbances (p < 0.001). Moreover, these symptoms also significantly affected patients’ social dimension in terms of satisfaction with participation in social roles (p < 0.001, p < 0.05, and p < 0.001 for belly pain, diarrhea, and bloating, respectively) and physical functions (p < 0.001). The results were virtually the same in a multivariable analysis adjusted by age, gender, body mass index (BMI), and disease duration. Conclusions: Even during remission, gastrointestinal symptoms are the main factors that influence quality of life in IBD patients. This exploratory study highlights the need to adopt validated questionnaires in clinical practice, and demonstrates that PROMIS is a valid, objective, and standardized instrument that can help nursing staff to better define the consequences of the disease in a patient’s daily life.

The Impact of Asthma on Quality-of-Life (QoL) and Other Patient-Reported Outcomes: The Patient's Perspective

2006 ◽  
Vol 117 (2) ◽  
pp. S270
Author(s):  
S.P. McKenna ◽  
D.M. Meads ◽  
K.M. Beusterien ◽  
R. Flood ◽  
H. Lau ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Patient Reported Outcomes ◽  
Patient’S Perspective ◽  
Patient Reported ◽  
The Impact

scholarly journals The Effect of Sports on Perceived Quality of Life of People with Visual Disability

2018 ◽  
Vol 20 (4) ◽  
pp. 289
Author(s):  
Ronailde Braga Guerra ◽  
Jaqueline Freitas de Oliveira Neiva ◽  
Pedro Manoel dos Santos ◽  
Ericson Oliveira de Aragão ◽  
Leonardo Pimenta ◽  
...  
Keyword(s):  
Quality Of Life ◽  
General Health ◽  
Perceived Quality ◽  
Visual Disability ◽  
Visual Disorder ◽  
Perceived Quality Of Life ◽  
Different Characteristics ◽  
The Impact ◽  
Physically Inactive

A prática esportiva melhora a qualidade de vida de pessoas com diferentes características, mas ainda não há informações sobre o impacto do esporte na qualidade de vida de pessoas com deficiência visual. O objetivo deste estudo foi identificar a percepção da qualidade de vida de atletas cegos de futebol de cinco e de goalball e compará-la com a qualidade de vida percebida de pessoas com deficiência visual fisicamente inativas. Trinta e sete homens com deficiência visual, separados em três grupos: 12 atletas de futebol de cinco (idade: M = 27,3 anos, DP = 10,2), 13 atletas de goalball (idade: M = 30,3 anos, DP = 7,0) e 12 pessoas fisicamente inativas (idade: M = 25,3 anos, DP = 2,3), responderam ao questionário WHOQOL-Bref. Atletas com deficiência visual obtiveram maior pontuação na Qualidade de Vida Global e Saúde Geral e em todos os domínios do WHOQOL-Bref do que pessoas fisicamente inativas. Não houve diferença entre a qualidade de vida percebida dos atletas de futebol e de goalball. Portanto, a despeito do tipo de esporte, sua prática está relacionada a uma melhor qualidade de vida de pessoas com deficiência visual.Palavras-chave: Cego. Futebol de Cegos. Futebol de Cinco. Goalball. WHOQOL-Bref.AbstractSports practice improves quality of life of people with different characteristics, but there is still no information about the impact of sport on quality of life among people with visual disorder. The aim of this study was to identify the perceived quality of life of blind football and goalball athletes and to compare it to perceived quality of life of physically inactive people with visual disorder. Thirty seven men with visual disorder, separated into three groups: 12 blind football athletes (age: M = 27.3 years, SD = 10.2), 13 goalball athletes (age: M = 30.3 years, SD = 7.0) and 12 physically inactive people (age: M = 25.3 years, SD = 2.3), answered the WHOQOL-Bref questionnaire. Athletes with visual disorder obtained a higher score in the Overall Quality of Live and General Health and in all domains of the WHOQOL-Bref than physically inactive people. There was no difference between the perceived quality of life of football and goalball athletes. Therefore, despite the type of sport, its practice is related to a better quality of life of people with visual disorder.Keywords: Blind. Blind Football. Football Five-a-side. Goalball. WHOQOL-Bref.

scholarly journals The Relationship Between Responsible Tourism Practice, Destination Sustainability and Quality of Life: Perspective of Marine National Park Communities

2021 ◽  
Vol 16 (5) ◽  
pp. 895-901
Author(s):  
Thanin Sangkhaduang ◽  
Parichart Visuthismajarn ◽  
Noodchanath Kongchouy
Keyword(s):  
Quality Of Life ◽  
National Park ◽  
Structural Equation ◽  
Perceived Quality ◽  
Ethical Consumption ◽  
Equation Modeling ◽  
Perceived Quality Of Life ◽  
The Impact ◽  
Responsible Tourism

An ideal responsible tourism practice has become the most significant role and principle for modern sustainable tourism development concept. Responsible tourism practice promotes better for tourists visit and enhances the quality of life of host communities in the destination by encouraging ethical consumption and production in all stakeholders. This paper attempted to determine the impact of host communities’ perceived responsible tourism practice on perceived destination sustainability and their quality of life as well as the impact of host communities’ perceived destination sustainability on perceived quality of life. The study was conducted with 355 participants from host communities in Haad Chao Mai Marine National Park, Thailand. Self-administered questionnaires were used to collect the data. The collected data were analyzed by using structural equation modeling (SEM). The results revealed that perceived responsible tourism practice had a significant impact on perceived destination sustainability and perceived quality of life. Additionally, perceived destination sustainability influenced perceived quality of life. As such, embedding responsible tourism practice in destination development plan can enable destination sustainability and better quality of life of host communities and it might make the park successful ecotourism destination.

Health-related quality of life/patient-reported outcomes in relapsed ovarian cancer: Results from a randomized phase III study of trabectedin with pegylated liposomal doxorubicin (PLD) versus PLD alone

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. 5526-5526
Author(s):  
C. N. Krasner ◽  
A. Poveda ◽  
T. Herzog ◽  
J. Vermorken ◽  
B. Monk ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Ovarian Cancer ◽  
Health Status ◽  
Patient Reported Outcomes ◽  
Phase Iii ◽  
Gi Symptoms ◽  
Patient Reported ◽  
Phase Iii Study ◽  
The Impact

5526 Background: In an open-label, multicenter, randomized phase III study comparing the combination of trabectedin and PLD to PLD alone in patients with relapsed ovarian cancer, the combination demonstrated significantly improved progression free survival and response rates, manageable non-cumulative toxicity, and fewer PLD-associated adverse events. We studied the impact of the combination of trabectedin with PLD on the quality of life (QoL)/patient-reported outcomes (PRO) evaluated as part of the trial. Methods: QoL/PRO questionnaires, EORTC-QLQ C30, OV28, and EQ-5D were completed by patients at screening and on Day 1 of every other treatment cycle starting with Cycle 1, and at the end-of-treatment visit. Global health status/QoL, fatigue, rain subscales from QLQ C30, and abdominal pain/GI symptoms scale from OV28 were chosen a priori for primary analyses. Other scales of the three questionnaires were analyzed on a supportive basis. Results: A total of 672 patients were randomized. 663 (98%) completed at least the baseline questionnaires. Median cycles of treatment was 6 (131 days) for the combination arm and 5 (143 days) for the monotherapy arm. Mixed effects models (using a covariance structure of AR[1]) predicting the score at baseline and follow-up scores as a function of treatment, days after baseline, and interaction between treatment and days after baseline showed no significant differences between the treatment arms for any of the prespecified scales. Similar analyses of other scales, including EQ-5D Health Index scores and Health State on the Visual Analog Scale, support the findings. Conclusions: The addition of trabectedin to PLD results in superior efficacy in patients with relapsed ovarian cancer, with no added decrement to overall health status as assessed by PRO. [Table: see text]

Sign in / Sign up

Export Citation Format

Share Document