scholarly journals Absolute choline tissue concentration mapping for prostate cancer localization and characterization using 3D 1 H MRSI without water‐signal suppression

2021 ◽  
Author(s):  
Nassim Tayari ◽  
Alan J. Wright ◽  
Arend Heerschap
Keyword(s):  
Prostate Cancer ◽  
Tissue Concentration ◽  
Signal Suppression ◽  
Water Signal ◽  
Concentration Mapping

scholarly journals Whole-body magnetic resonance imaging (WB-MRI) with diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) in prostate cancer: Prevalence and clinical significance of incidental findings

2021 ◽  
pp. 20210459
Author(s):  
Soma Kumasaka ◽  
Shunichi Motegi ◽  
Yuka Kumasaka ◽  
Tatsuya Nishikata ◽  
Masami Otomo ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Incidental Findings ◽  
Whole Body ◽  
Whole Body Imaging ◽  
Resonance Imaging ◽  
Body Imaging ◽  
Signal Suppression ◽  
Body Magnetic Resonance Imaging ◽  
Clinically Significant

Objective: Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) is now recommended as a first-line staging modality in prostate cancer patients, and the widespread use of DWIBS may lead to an increased frequency of incidental findings. The aim of this study was to evaluate the prevalence and clinical significance of incidental findings on whole-body magnetic resonance imaging (WB-MRI) with DWIBS. Methods: Data from 124 patients with prostate cancer (age, 76.5 ± 5.6 years), who underwent 1.5 T WB-MRI with STIR, TSE-T2, TSE-T1, In/Out GRE, and DWIBS sequences, were retrospectively analyzed. Findings unrelated to prostate cancer were considered as incidental findings and categorized into two groups based on their clinical implications, as follow: imaging follow-up or additional examinations was required (significant incidental findings) and no need to additional work-up (non-significant incidental findings). A Chi-square test was performed to compare the differences in the prevalence of significant incidental findings based on age (≤75 and>75 years old). Results: A total of 334 incidental findings were found, with 8.1% (n = 27) as significant incidental findings. Significant incidental findings were more frequent in patients over 75 years old than those of 75 years old or younger (28.6% vs  11.1%, p = 0.018). Conclusion: Clinically significant incidental findings, which required imaging follow-up or additional examinations, were commonly observed in prostate cancer patients on WB-MRI/DWIBS. Advances in knowledge: Some incidental findings were clinically significant which may lead to changes in treatment strategy. Checking the entire organ carefully for abnormalities, and reporting any incidental findings detected are important.

scholarly journals Robust NMR water signal suppression for demanding analytical applications

The Analyst ◽  
2016 ◽  
Vol 141 (1) ◽  
pp. 236-242 ◽  
Author(s):  
Juan A. Aguilar ◽  
Simon. J. Kenwright
Keyword(s):  
Pulse Sequences ◽  
General Purpose ◽  
Analytical Applications ◽  
Signal Suppression ◽  
Water Signal ◽  
Design And Application

We describe the design and application of robust, general-purpose water signal suppression pulse sequences well suited to chemometric work.

Water signal suppression via self-refocused excitation sequences

1991 ◽  
Vol 91 (1) ◽  
pp. 120-127
Author(s):  
Ladislav Půček ◽  
Edmond Wang ◽  
Juli Feigon ◽  
Zenon Starčuk ◽  
Vladimír Sklenář
Keyword(s):  
Signal Suppression ◽  
Water Signal

scholarly journals Whole-body magnetic resonance imaging (WB-MRI) with diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) in prostate cancer: Prevalence and clinical significance of incidental findings

2021 ◽  
Author(s):  
Soma Kumasaka ◽  
Shunichi Motegi ◽  
Yuka Kumasaka ◽  
Tatsuya Nishikata ◽  
Masami Otomo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Incidental Findings ◽  
Whole Body ◽  
Whole Body Imaging ◽  
Resonance Imaging ◽  
Body Imaging ◽  
Signal Suppression ◽  
Body Magnetic Resonance Imaging

Abstract Background Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) is now recommended as a first-line staging modality in prostate cancer patients, and the widespread use of DWIBS may lead to an increased frequency of incidental findings. The aim of this study is to evaluate the prevalence and clinical significance of incidental findings detected on whole-body magnetic resonance imaging (WB-MRI) with DWIBS in patients with prostate cancer. Methods Data from 124 patients (age, 76.5 ± 5.6 years; range, 60–90) with pathologically confirmed prostate cancer, who underwent WB-MRI between December 2016 and April 2020, were retrospectively analyzed. Findings unrelated to prostate cancer were considered as incidental findings and categorized into two groups based on their clinical implications, as follow: imaging follow-up or additional examinations was required (significant incidental findings) and no need to additional work-up (non-significant incidental findings). A Chi-square test was performed to compare the differences in the prevalence of significant incidental findings based on age (≤ 75 and > 75 years old). Results A total of 334 incidental findings were found, with 8.1% (n = 27) as significant incidental findings and 91.9% (n = 307) as non-significant incidental findings. Significant incidental findings were more frequent in patients over 75 years old than those of 75 years old or younger (28.6% vs 11.1%, p = 0.018). Nineteen of the 27 significant incidental findings (70.4%) were observed on non-DWIBS sequences. Conclusion Clinically significant incidental findings, which required imaging follow-up or additional examinations, were commonly observed in patients with prostate cancer on WB-MRI/DWIBS.

scholarly journals On the measurement of 15N–{1H} nuclear Overhauser effects. 2. Effects of the saturation scheme and water signal suppression

2010 ◽  
Vol 207 (2) ◽  
pp. 294-303 ◽  
Author(s):  
Fabien Ferrage ◽  
Amy Reichel ◽  
Shibani Battacharya ◽  
David Cowburn ◽  
Ranajeet Ghose
Keyword(s):  
Signal Suppression ◽  
Water Signal ◽  
Nuclear Overhauser ◽  
Nuclear Overhauser Effects

Water signal suppression by T2-relaxation enhancement promoted by Dy(III) complexes

1991 ◽  
Vol 29 (13) ◽  
pp. S85-S88 ◽  
Author(s):  
Silvio Aime ◽  
Mauro Botta ◽  
Luca Barbero ◽  
Fulvio Uggeri ◽  
Franco Fedeli
Keyword(s):  
T2 Relaxation ◽  
Signal Suppression ◽  
Water Signal

scholarly journals Whole-body MRI: detecting bone metastases from prostate cancer

2021 ◽  
Author(s):  
Katsuyuki Nakanishi ◽  
Junichiro Tanaka ◽  
Yasuhiro Nakaya ◽  
Noboru Maeda ◽  
Atsuhiko Sakamoto ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Bone Metastases ◽  
Automatic Segmentation ◽  
Whole Body ◽  
Therapeutic Effects ◽  
Imaging Protocol ◽  
Adc Value ◽  
Signal Suppression ◽  
Apparent Diffusion ◽  
Body Magnetic Resonance Imaging

AbstractWhole-body magnetic resonance imaging (WB-MRI) is currently used worldwide for detecting bone metastases from prostate cancer. The 5-year survival rate for prostate cancer is > 95%. However, an increase in survival time may increase the incidence of bone metastasis. Therefore, detecting bone metastases is of great clinical interest. Bone metastases are commonly located in the spine, pelvis, shoulder, and distal femur. Bone metastases from prostate cancer are well-known representatives of osteoblastic metastases. However, other types of bone metastases, such as mixed or inter-trabecular type, have also been detected using MRI. MRI does not involve radiation exposure and has good sensitivity and specificity for detecting bone metastases. WB-MRI has undergone gradual developments since the last century, and in 2004, Takahara et al., developed diffusion-weighted Imaging (DWI) with background body signal suppression (DWIBS). Since then, WB-MRI, including DWI, has continued to play an important role in detecting bone metastases and monitoring therapeutic effects. An imaging protocol that allows complete examination within approximately 30 min has been established. This review focuses on WB-MRI standardization and the automatic calculation of tumor total diffusion volume (tDV) and mean apparent diffusion coefficient (ADC) value. In the future, artificial intelligence (AI) will enable shorter imaging times and easier automatic segmentation.

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