Optimization of adiabatic pulses for pulsed arterial spin labeling at 7 tesla: Comparison with pseudo‐continuous arterial spin labeling

2021 ◽  
Vol 85 (6) ◽  
pp. 3227-3240
Author(s):  
Kai Wang ◽  
Xingfeng Shao ◽  
Lirong Yan ◽  
Samantha J. Ma ◽  
Jin Jin ◽  
...  
Keyword(s):  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
7 Tesla ◽  
Adiabatic Pulses ◽  
Continuous Arterial Spin Labeling

scholarly journals Hybrid ‐shimming and gradient adaptions for improved pseudo‐continuous arterial spin labeling at 7 Tesla

2021 ◽  
Author(s):  
Christian R. Meixner ◽  
Christian K. Eisen ◽  
Sebastian Schmitter ◽  
Max Müller ◽  
Jürgen Herrler ◽  
...  
Keyword(s):  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
7 Tesla ◽  
Continuous Arterial Spin Labeling

scholarly journals Laminar perfusion imaging with zoomed arterial spin labeling at 7 Tesla

2021 ◽  
Author(s):  
Xingfeng Shao ◽  
Fanhua Guo ◽  
Qinyang Shou ◽  
Kai Wang ◽  
Kay Jann ◽  
...  
Keyword(s):  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
7 Tesla ◽  
Pial Arteries ◽  
Cortical Input ◽  
Thalamic Input ◽  
Specificity And Sensitivity ◽  
Deep Layers ◽  
Arterial Transit Time ◽  
Continuous Arterial Spin Labeling

Laminar fMRI based on BOLD and CBV contrast at ultrahigh magnetic fields has been applied for studying the dynamics of mesoscopic brain networks. However, the quantitative interpretations of BOLD/CBV fMRI results are confounded by different baseline physiology across cortical layers. Here we introduce a novel 3D zoomed pseudo-continuous arterial spin labeling technique at 7T that offers the unique capability for quantitative measurements of laminar cerebral blood flow (CBF) both at rest and during task activation with high spatial specificity and sensitivity. We found arterial transit time in superficial layers is ~100 msec shorter than in middle/deep layers revealing the dynamics of labeled blood flowing from pial arteries to downstream microvasculature. Resting state CBF peaked in the middle layers which is highly consistent with microvascular density measured from human cortex specimens. Finger tapping induced a robust two-peak laminar profile of CBF increases in the superficial (somatosensory and premotor input) and deep (spinal output) layers of M1, while finger brushing task induced a weaker CBF increase in superficial layers (somatosensory input). We further demonstrated that top-down attention induced a predominant CBF increase in deep layers and a smaller CBF increase on top of the lower baseline CBF in superficial layers of V1 (feedback cortical input), while bottom-up stimulus driven activity peaked in the middle layers (feedforward thalamic input). These quantitative laminar profiles of perfusion activity suggest an important role of M1 superficial layers for the computation of finger movements, and that visual attention may amplify deep layer output to the subcortex.

Vessel-selective 4D-MR angiography using super-selective pseudo-continuous arterial spin labeling may be a useful tool for assessing brain AVM hemodynamics

2020 ◽  
Vol 30 (12) ◽  
pp. 6452-6463 ◽  
Author(s):  
Osamu Togao ◽  
Makoto Obara ◽  
Michael Helle ◽  
Koji Yamashita ◽  
Kazufumi Kikuchi ◽  
...  
Keyword(s):  
Arterial Spin Labeling ◽  
Mr Angiography ◽  
Spin Labeling ◽  
Brain Avm ◽  
Continuous Arterial Spin Labeling

Assessment of glioma response to radiotherapy using 3D pulsed-continuous arterial spin labeling and 3D segmented volume

2016 ◽  
Vol 85 (11) ◽  
pp. 1987-1992 ◽  
Author(s):  
Peng Wang ◽  
Jianrui Li ◽  
Qiang Diao ◽  
YuanKai Lin ◽  
Jun Zhang ◽  
...  
Keyword(s):  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Continuous Arterial Spin Labeling ◽  
Segmented Volume
Sign in / Sign up

Export Citation Format

Share Document