scholarly journals Cerebral oxygen extraction fraction: Comparison of dual‐gas challenge calibrated BOLD with CBF and challenge‐free gradient echo QSM+qBOLD

2020 ◽  
Vol 85 (2) ◽  
pp. 953-961
Author(s):  
Junghun Cho ◽  
Yuhan Ma ◽  
Pascal Spincemaille ◽  
Gilbert Bruce Pike ◽  
Yi Wang
Keyword(s):  
Oxygen Extraction Fraction ◽  
Oxygen Extraction ◽  
Cerebral Oxygen ◽  
Gradient Echo ◽  
Extraction Fraction ◽  
Fraction Comparison

scholarly journals Quantitative Measurement of Cerebral Oxygen Extraction Fraction Using MRI in Patients with MELAS

PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e79859 ◽  
Author(s):  
Lei Yu ◽  
Sheng Xie ◽  
Jiangxi Xiao ◽  
Zhaoxia Wang ◽  
Xiaodong Zhang
Keyword(s):  
Quantitative Measurement ◽  
Oxygen Extraction Fraction ◽  
Oxygen Extraction ◽  
Cerebral Oxygen ◽  
Extraction Fraction

scholarly journals Identification of Collaterally Perfused Areas following Focal Cerebral Ischemia in the Rat by Comparison of Gradient Echo and Diffusion-Weighted MRI

1995 ◽  
Vol 15 (4) ◽  
pp. 578-586 ◽  
Author(s):  
S. A. Roussel ◽  
N. van Bruggen ◽  
M. D. King ◽  
D. G. Gadian
Keyword(s):  
Signal Intensity ◽  
Magnetic Resonance Images ◽  
Core Area ◽  
Oxygen Extraction Fraction ◽  
Oxygen Extraction ◽  
Great Promise ◽  
Gradient Echo ◽  
The Core ◽  
Extraction Fraction ◽  
Diffusion Weighted

Diffusion-weighted (DW) and gradient echo (GE) magnetic resonance images were acquired before and after occlusion of the middle cerebral artery (MCA) in the rat. Upon occlusion, an increase in DW imaging signal intensity was observed in a core area within the MCA territory, most likely reflecting cytotoxic edema. The signal from GE images, which is sensitive to changes in the absolute amount of deoxyhemoglobin, decreased following ischemia within a region that extended beyond the core area observed with DW imaging. This hypointensity is attributed to increases in blood volume and/or oxygen extraction fraction, which result from a decrease in perfusion pressure in the collaterally perfused area. The evolution of the GE imaging signal intensity from different regions was studied for 3.5 h following the occlusion. In the core area, the GE imaging signal returned towards baseline values after ∼1–2 h, while it remained stable in the surrounding area. This feature may reflect a decrease in hematocrit due to microcirculatory defect and/or a decrease in the oxygen extraction fraction due to ongoing infarction of the tissue and may indicate that tissue recovery is severely compromised. The combined use of DW and GE imaging offers great promise for the noninvasive identification of specific pathological events with high spatial resolution.

scholarly journals Mapping of Cerebral Oxygen Extraction Fraction Changes with Susceptibility-weighted Phase Imaging

Radiology ◽  
2011 ◽  
Vol 261 (3) ◽  
pp. 930-936 ◽  
Author(s):  
Yuri Zaitsu ◽  
Kohsuke Kudo ◽  
Satoshi Terae ◽  
Rie Yazu ◽  
Kinya Ishizaka ◽  
...  
Keyword(s):  
Oxygen Extraction Fraction ◽  
Oxygen Extraction ◽  
Phase Imaging ◽  
Cerebral Oxygen ◽  
Extraction Fraction
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