scholarly journals Cerebrospinal fluid pulse wave velocity measurements: In vitro and in vivo evaluation of a novel multiband cine phase‐contrast MRI sequence

2020 ◽  
Vol 85 (1) ◽  
pp. 197-208
Author(s):  
Kristina Sonnabend ◽  
Gerrit Brinker ◽  
David Maintz ◽  
Alexander C. Bunck ◽  
Kilian Weiss
Keyword(s):  
Cerebrospinal Fluid ◽  
Pulse Wave Velocity ◽  
Phase Contrast ◽  
Pulse Wave ◽  
Velocity Measurements ◽  
Phase Contrast Mri ◽  
In Vivo Evaluation ◽  
Cine Phase Contrast

Design and Functional Testing of a Novel Blood Pulse Wave Velocity Sensor

2017 ◽  
Vol 12 (1) ◽  
Author(s):  
Marit H. N. van Velzen ◽  
Arjo J. Loeve ◽  
Egbert G. Mik ◽  
Sjoerd P. Niehof
Keyword(s):  
Pilot Study ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Maximum Deviation ◽  
Functional Testing ◽  
Flow Mediated Dilation ◽  
Normal Range

The multiphotodiode array (MPA) is a novel transmission photoplethysmography (PPG) sensor to measure pulse wave velocity (PWV) in the finger. To validate the MPA, a setup was built to generate a red laser dot traveling over the MPA with known and constant scanning velocities. These scanning velocities were chosen to include speeds at least twice as high as those found in the normal range of PWV in healthy populations and were set at 12.9, 25.8, 36, or 46.7 m/s. The aim of this study was to verify the functionality of the MPA: performing local noninvasive PWV measurements. To illustrate the applicability of the MPA in clinical practice, an in vivo pilot study was conducted using the flow-mediated dilation (FMD) technique. The in vitro accuracy of the MPA was ±0.2%, 0.3%, 0.5%, and 0.6% at the applied scanning velocities. The MPA can measure PWVs with a maximum deviation of 3.0%. The in vivo pilot study showed a PWV before the FMD of 1.1±0.2 m/s. These results suggest that this novel MPA can reliably and accurately measure PWV within clinically relevant ranges and even well beyond.

Quantification of vessel wall motion and cyclic strain using cine phase contrast MRI: In vivo validation in the porcine aorta

2004 ◽  
Vol 52 (2) ◽  
pp. 286-295 ◽  
Author(s):  
Mary T. Draney ◽  
Frank R. Arko ◽  
Marcus T. Alley ◽  
Michael Markl ◽  
Robert J. Herfkens ◽  
...  
Keyword(s):  
Vessel Wall ◽  
Phase Contrast ◽  
Wall Motion ◽  
Cyclic Strain ◽  
Phase Contrast Mri ◽  
Cine Phase Contrast ◽  
In Vivo Validation

scholarly journals Noninvasive Method for Measuring Local Pulse Wave Velocity by Dual Pulse Wave Doppler: In Vitro and In Vivo Studies

PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0120482 ◽  
Author(s):  
Zhen Wang ◽  
Yong Yang ◽  
Li-jun Yuan ◽  
Jie Liu ◽  
Yun-you Duan ◽  
...  
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
In Vivo Studies ◽  
Noninvasive Method

scholarly journals Direction and magnitude of cerebrospinal fluid flow vary substantially across central nervous system diseases

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Per Kristian Eide ◽  
Lars Magnus Valnes ◽  
Erika Kristina Lindstrøm ◽  
Kent-Andre Mardal ◽  
Geir Ringstad
Keyword(s):  
Central Nervous System ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Phase Contrast ◽  
Flow Volume ◽  
Nervous System Diseases ◽  
Central Nervous System Diseases ◽  
Csf Flow ◽  
Phase Contrast Mri

Abstract Background Several central nervous system diseases are associated with disturbed cerebrospinal fluid (CSF) flow patterns and have typically been characterized in vivo by phase-contrast magnetic resonance imaging (MRI). This technique is, however, limited by its applicability in space and time. Phase-contrast MRI has yet to be compared directly with CSF tracer enhanced imaging, which can be considered gold standard for assessing long-term CSF flow dynamics within the intracranial compartment. Methods Here, we studied patients with various CSF disorders and compared MRI biomarkers of CSF space anatomy and phase-contrast MRI at level of the aqueduct and cranio-cervical junction with dynamic intrathecal contrast-enhanced MRI using the contrast agent gadobutrol as CSF tracer. Tracer enrichment of cerebral ventricles was graded 0–4 by visual assessment. An intracranial pressure (ICP) score was used as surrogate marker of intracranial compliance. Results The study included 94 patients and disclosed marked variation of CSF flow measures across disease categories. The grade of supra-aqueductal reflux of tracer varied, with strong reflux (grades 3–4) in half of patients. Ventricular tracer reflux correlated with stroke volume and aqueductal CSF pressure gradient. CSF flow in the cerebral aqueduct was retrograde (from 4th to 3rd ventricle) in one third of patients, with estimated CSF net flow volume about 1.0 L/24 h. In the cranio-cervical junction, net flow was cranially directed in 78% patients, with estimated CSF net flow volume about 4.7 L/24 h. Conclusions The present observations provide in vivo quantitative evidence for substantial variation in direction and magnitude of CSF flow, with re-direction of aqueductal flow in communicating hydrocephalus, and significant extra-cranial CSF production. The grading of ventricular reflux of tracer shows promise as a clinical useful method to assess CSF flow pattern disturbances in patients. Graphic abstract

Assessment of carotid stiffness by measuring carotid pulse wave velocity using a single‐slice oblique‐sagittal phase‐contrast MRI

2021 ◽  
Author(s):  
Soroush Heidari Pahlavian ◽  
Steven Yong Cen ◽  
Xiaoming Bi ◽  
Danny J. J. Wang ◽  
Helena Chang Chui ◽  
...  
Keyword(s):  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Phase Contrast ◽  
Pulse Wave ◽  
Phase Contrast Mri ◽  
Single Slice ◽  
Carotid Stiffness
Sign in / Sign up

Export Citation Format

Share Document