Macromolecular proton fraction mapping based on spin‐lock magnetic resonance imaging

2020 ◽  
Vol 84 (6) ◽  
pp. 3157-3171
Author(s):  
Jian Hou ◽  
Vincent Wai‐Sun Wong ◽  
Baiyan Jiang ◽  
Yi‐Xiang Wang ◽  
Grace Lai‐Hung Wong ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Spin Lock

Three-dimensional spin-lock magnetic resonance imaging of the shoulder joint at 3 T: initial experience

2007 ◽  
Vol 36 (12) ◽  
pp. 1171-1175 ◽  
Author(s):  
Renata La Rocca Vieira ◽  
Sait Kubilay Pakin ◽  
Conrado Furtado de Albuquerque Cavalcanti ◽  
Mark Schweitzer ◽  
Ravinder Regatte
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Shoulder Joint ◽  
Three Dimensional ◽  
Initial Experience ◽  
Resonance Imaging ◽  
Spin Lock

Spin-Lock Magnetic Resonance Imaging of Muscle in Patients With Autosomal Recessive Limb Girdle Muscular Dystrophy

2000 ◽  
Vol 10 (2) ◽  
pp. 73-77 ◽  
Author(s):  
Malgorzata B Franczak ◽  
John L Ulmer ◽  
Safwan Jaradeh ◽  
James D McDaniel ◽  
Leighton P Mark ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Muscular Dystrophy ◽  
Autosomal Recessive ◽  
Limb Girdle Muscular Dystrophy ◽  
Resonance Imaging ◽  
Spin Lock

scholarly journals Mapping Brain Glucose Uptake with Chemical Exchange-Sensitive Spin-Lock Magnetic Resonance Imaging

2014 ◽  
Vol 34 (8) ◽  
pp. 1402-1410 ◽  
Author(s):  
Tao Jin ◽  
Hunter Mehrens ◽  
Kristy S Hendrich ◽  
Seong-Gi Kim
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Chemical Exchange ◽  
Resonance Imaging ◽  
Spin Lock ◽  
Intravenous Injections ◽  
Glucose Levels ◽  
Metabolic Properties ◽  
Magnetic Resonance Imaging Mri

Uptake of administered D-glucose (Glc) or 2-deoxy-D-glucose (2DG) has been indirectly mapped through the chemical exchange (CE) between glucose hydroxyl and water protons using CE-dependent saturation transfer (glucoCEST) magnetic resonance imaging (MRI). We propose an alternative technique—on-resonance CE-sensitive spin-lock (CESL) MRI—to enhance responses to glucose changes. Phantom data and simulations suggest higher sensitivity for this ‘glucoCESL’ technique (versus glucoCEST) in the intermediate CE regime relevant to glucose. Simulations of CESL signals also show insensitivity to B0-fluctuations. Several findings are apparent from in vivo glucoCESL studies of rat brain at 9.4 Tesla with intravenous injections. First, dose-dependent responses are nearly linearly for 0.25-, 0.5-, and 1-g/kg Glc administration (obtained with 12-second temporal resolution), with changes robustly detected for all doses. Second, responses at a matched dose of 1 g/kg are much larger and persist for a longer duration for 2DG versus Glc administration, and are minimal for mannitol as an osmolality control. And third, with similar increases in steady-state blood glucose levels, glucoCESL responses are ~2.2 times higher for 2DG versus Glc, consistent with their different metabolic properties. Overall, we show that glucoCESL MRI could be a highly sensitive and quantifiable tool for glucose transport and metabolism studies.

Spin-lock imaging in contrast enhanced magnetic resonance imaging of human gliomas

1996 ◽  
Vol 3 ◽  
pp. S170-S172 ◽  
Author(s):  
Hannu J. Aronen ◽  
Teemu K. Peltonen ◽  
Jukka I. Tanttu ◽  
Leena M. Sipilä ◽  
Marko T. Ruhala ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Human Gliomas ◽  
Spin Lock ◽  
Contrast Enhanced

Spin lock magnetic resonance imaging in the differentiation of hepatic haemangiomas and metastases

1995 ◽  
Vol 68 (815) ◽  
pp. 1198-1203 ◽  
Author(s):  
J T Halavaara ◽  
A E Lamminen ◽  
S Bondestam ◽  
R E Sepponen ◽  
J I Tanttu
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Spin Lock

Functional information from magnetic resonance imaging

1995 ◽  
Vol 53 ◽  
pp. 84-85
Author(s):  
Alan P. Koretsky ◽  
Afonso Costa e Silva ◽  
Yi-Jen Lin
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Cancer Biology ◽  
Imaging Modality ◽  
Magnetic Resonance Images ◽  
Great Success ◽  
Functional Information ◽  
Resonance Imaging ◽  
High Resolution Mri

Magnetic resonance imaging (MRI) has become established as an important imaging modality for the clinical management of disease. This is primarily due to the great tissue contrast inherent in magnetic resonance images of normal and diseased organs. Due to the wide availability of high field magnets and the ability to generate large and rapidly switched magnetic field gradients there is growing interest in applying high resolution MRI to obtain microscopic information. This symposium on MRI microscopy highlights new developments that are leading to increased resolution. The application of high resolution MRI to significant problems in developmental biology and cancer biology will illustrate the potential of these techniques.In combination with a growing interest in obtaining high resolution MRI there is also a growing interest in obtaining functional information from MRI. The great success of MRI in clinical applications is due to the inherent contrast obtained from different tissues leading to anatomical information.

Functional Magnetic Resonance Imaging Measures of Blood Flow Patterns in the Human Auditory Cortex in Response to Sound

1998 ◽  
Vol 41 (3) ◽  
pp. 538-548 ◽  
Author(s):  
Sean C. Huckins ◽  
Christopher W. Turner ◽  
Karen A. Doherty ◽  
Michael M. Fonte ◽  
Nikolaus M. Szeverenyi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Blood Flow ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Speech Stimuli ◽  
Complex Stimuli ◽  
Scanning Session ◽  
Auditory Research

Functional Magnetic Resonance Imaging (fMRI) holds exciting potential as a research and clinical tool for exploring the human auditory system. This noninvasive technique allows the measurement of discrete changes in cerebral cortical blood flow in response to sensory stimuli, allowing determination of precise neuroanatomical locations of the underlying brain parenchymal activity. Application of fMRI in auditory research, however, has been limited. One problem is that fMRI utilizing echo-planar imaging technology (EPI) generates intense noise that could potentially affect the results of auditory experiments. Also, issues relating to the reliability of fMRI for listeners with normal hearing need to be resolved before this technique can be used to study listeners with hearing loss. This preliminary study examines the feasibility of using fMRI in auditory research by performing a simple set of experiments to test the reliability of scanning parameters that use a high resolution and high signal-to-noise ratio unlike that presently reported in the literature. We used consonant-vowel (CV) speech stimuli to investigate whether or not we could observe reproducible and consistent changes in cortical blood flow in listeners during a single scanning session, across more than one scanning session, and in more than one listener. In addition, we wanted to determine if there were differences between CV speech and nonspeech complex stimuli across listeners. Our study shows reproducibility within and across listeners for CV speech stimuli. Results were reproducible for CV speech stimuli within fMRI scanning sessions for 5 out of 9 listeners and were reproducible for 6 out of 8 listeners across fMRI scanning sessions. Results of nonspeech complex stimuli across listeners showed activity in 4 out of 9 individuals tested.

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