Investigating the origin of pH‐sensitive magnetization transfer ratio asymmetry MRI contrast during the acute stroke: Correction of T
            1
            change reveals the dominant amide proton transfer MRI signal

Limin Wu; Liang Jiang; Phillip Zhe Sun

doi:10.1002/mrm.28313

Investigating the origin of pH‐sensitive magnetization transfer ratio asymmetry MRI contrast during the acute stroke: Correction of T 1 change reveals the dominant amide proton transfer MRI signal

Magnetic Resonance in Medicine ◽

10.1002/mrm.28313 ◽

2020 ◽

Vol 84 (5) ◽

pp. 2702-2712 ◽

Cited By ~ 1

Author(s):

Limin Wu ◽

Liang Jiang ◽

Phillip Zhe Sun

Keyword(s):

Proton Transfer ◽

Acute Stroke ◽

Magnetization Transfer ◽

Ph Sensitive ◽

Amide Proton ◽

Magnetization Transfer Ratio ◽

Mri Contrast ◽

Transfer Ratio ◽

Amide Proton Transfer

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Accuracy and uncertainty of asymmetric magnetization transfer ratio quantification for amide proton transfer (APT) imaging at 3T: A Monte Carlo study

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) ◽

10.1109/embc.2013.6610705 ◽

2013 ◽

Author(s):

Jing Yuan ◽

Qinwei Zhang ◽

Yi-Xiang Wang ◽

Juan Wei ◽

Jinyuan Zhou

Keyword(s):

Monte Carlo ◽

Proton Transfer ◽

Magnetization Transfer ◽

Monte Carlo Study ◽

Amide Proton ◽

Magnetization Transfer Ratio ◽

Transfer Ratio ◽

Amide Proton Transfer ◽

Apt Imaging

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pH-sensitive MRI demarcates graded tissue acidification during acute stroke ― pH specificity enhancement with magnetization transfer and relaxation-normalized amide proton transfer (APT) MRI

NeuroImage ◽

10.1016/j.neuroimage.2016.07.025 ◽

2016 ◽

Vol 141 ◽

pp. 242-249 ◽

Cited By ~ 29

Author(s):

Yingkun Guo ◽

Iris Yuwen Zhou ◽

Suk-Tak Chan ◽

Yu Wang ◽

Emiri T. Mandeville ◽

...

Keyword(s):

Proton Transfer ◽

Acute Stroke ◽

Magnetization Transfer ◽

Ph Sensitive ◽

Amide Proton ◽

Amide Proton Transfer

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Improving the detection sensitivity of pH-weighted amide proton transfer MRI in acute stroke patients using extrapolated semisolid magnetization transfer reference signals

Magnetic Resonance in Medicine ◽

10.1002/mrm.26799 ◽

2017 ◽

Vol 78 (3) ◽

pp. 871-880 ◽

Cited By ~ 26

Author(s):

Hye-Young Heo ◽

Yi Zhang ◽

Tina M. Burton ◽

Shanshan Jiang ◽

Yansong Zhao ◽

...

Keyword(s):

Proton Transfer ◽

Acute Stroke ◽

Magnetization Transfer ◽

Detection Sensitivity ◽

Amide Proton ◽

Stroke Patients ◽

Amide Proton Transfer ◽

Reference Signals

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Demonstration of magnetization transfer and relaxation normalized pH‐specific pulse‐amide proton transfer imaging in an animal model of acute stroke

Magnetic Resonance in Medicine ◽

10.1002/mrm.28223 ◽

2020 ◽

Vol 84 (3) ◽

pp. 1526-1533 ◽

Cited By ~ 3

Author(s):

Phillip Zhe Sun

Keyword(s):

Animal Model ◽

Proton Transfer ◽

Acute Stroke ◽

Magnetization Transfer ◽

Amide Proton ◽

Amide Proton Transfer ◽

Amide Proton Transfer Imaging

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pH-sensitive amide proton transfer effect dominates the magnetization transfer asymmetry contrast during acute ischemia-quantification of multipool contribution to in vivo CEST MRI

Magnetic Resonance in Medicine ◽

10.1002/mrm.26829 ◽

2017 ◽

Vol 79 (3) ◽

pp. 1602-1608 ◽

Cited By ~ 14

Author(s):

Yin Wu ◽

Iris Yuwen Zhou ◽

Dongshuang Lu ◽

Emiri Manderville ◽

Eng H. Lo ◽

...

Keyword(s):

Proton Transfer ◽

Magnetization Transfer ◽

Transfer Effect ◽

Ph Sensitive ◽

Amide Proton ◽

Acute Ischemia ◽

Amide Proton Transfer ◽

Cest Mri

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Fast correction of B 0 field inhomogeneity for pH‐specific magnetization transfer and relaxation normalized amide proton transfer imaging of acute ischemic stroke without Z‐spectrum

Magnetic Resonance in Medicine ◽

10.1002/mrm.28040 ◽

2019 ◽

Vol 83 (5) ◽

pp. 1688-1697 ◽

Cited By ~ 6

Author(s):

Phillip Zhe Sun

Keyword(s):

Ischemic Stroke ◽

Proton Transfer ◽

Acute Ischemic Stroke ◽

Magnetization Transfer ◽

Amide Proton ◽

Specific Magnetization ◽

Field Inhomogeneity ◽

Amide Proton Transfer ◽

Amide Proton Transfer Imaging

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Mapping tissue pH in an experimental model of acute stroke – Determination of graded regional tissue pH changes with non-invasive quantitative amide proton transfer MRI

NeuroImage ◽

10.1016/j.neuroimage.2019.02.022 ◽

2019 ◽

Vol 191 ◽

pp. 610-617 ◽

Cited By ~ 13

Author(s):

Enfeng Wang ◽

Yin Wu ◽

Jerry S. Cheung ◽

Takahiro Igarashi ◽

Limin Wu ◽

...

Keyword(s):

Proton Transfer ◽

Acute Stroke ◽

Experimental Model ◽

Amide Proton ◽

Tissue Ph ◽

Ph Changes ◽

Non Invasive ◽

Amide Proton Transfer

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Assessing Amide Proton Transfer (APT) MRI Contrast Origins in 9 L Gliosarcoma in the Rat Brain Using Proteomic Analysis

Molecular Imaging and Biology ◽

10.1007/s11307-015-0828-6 ◽

2015 ◽

Vol 17 (4) ◽

pp. 479-487 ◽

Cited By ~ 52

Author(s):

Kun Yan ◽

Zongming Fu ◽

Chen Yang ◽

Kai Zhang ◽

Shanshan Jiang ◽

...

Keyword(s):

Proton Transfer ◽

Rat Brain ◽

Proteomic Analysis ◽

Amide Proton ◽

Mri Contrast ◽

Amide Proton Transfer

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Amide proton transfer imaging with improved robustness to magnetic field inhomogeneity and magnetization transfer asymmetry using saturation with frequency alternating RF irradiation

Magnetic Resonance in Medicine ◽

10.1002/mrm.22912 ◽

2011 ◽

Vol 66 (5) ◽

pp. 1275-1285 ◽

Cited By ~ 76

Author(s):

Rachel Scheidegger ◽

Elena Vinogradov ◽

David C. Alsop

Keyword(s):

Magnetic Field ◽

Proton Transfer ◽

Magnetization Transfer ◽

Amide Proton ◽

Magnetic Field Inhomogeneity ◽

Field Inhomogeneity ◽

Amide Proton Transfer ◽

Amide Proton Transfer Imaging

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Quantitative assessment of amide proton transfer (APT) and nuclear overhauser enhancement (NOE) imaging with extrapolated semi-solid magnetization transfer reference (EMR) signals: Application to a rat glioma model at 4.7 tesla

Magnetic Resonance in Medicine ◽

10.1002/mrm.25581 ◽

2015 ◽

Vol 75 (1) ◽

pp. 137-149 ◽

Cited By ~ 69

Author(s):

Hye-Young Heo ◽

Yi Zhang ◽

Dong-Hoon Lee ◽

Xiaohua Hong ◽

Jinyuan Zhou

Keyword(s):

Proton Transfer ◽

Quantitative Assessment ◽

Magnetization Transfer ◽

Amide Proton ◽

Rat Glioma ◽

Nuclear Overhauser Enhancement ◽

Amide Proton Transfer ◽

Glioma Model ◽

Nuclear Overhauser ◽

Semi Solid

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