scholarly journals Motion‐robust, high‐SNR liver fat quantification using a 2D sequential acquisition with a variable flip angle approach

2020 ◽  
Vol 84 (4) ◽  
pp. 2004-2017
Author(s):  
Ruiyang Zhao ◽  
Yuxin Zhang ◽  
Xiaoke Wang ◽  
Timothy J. Colgan ◽  
Jennifer L. Rehm ◽  
...  
Keyword(s):  
Flip Angle ◽  
Liver Fat ◽  
Variable Flip Angle ◽  
Fat Quantification ◽  
Sequential Acquisition ◽  
Liver Fat Quantification

scholarly journals Accuracy of Liver Fat Quantification With Advanced CT, MRI, and Ultrasound Techniques: Prospective Comparison With MR Spectroscopy

2017 ◽  
Vol 208 (1) ◽  
pp. 92-100 ◽  
Author(s):  
Harald Kramer ◽  
Perry J. Pickhardt ◽  
Mark A. Kliewer ◽  
Diego Hernando ◽  
Guang-Hong Chen ◽  
...  
Keyword(s):  
Mr Spectroscopy ◽  
Liver Fat ◽  
Fat Quantification ◽  
Prospective Comparison ◽  
Liver Fat Quantification

scholarly journals Improved Folch Method for Liver-Fat Quantification

2021 ◽  
Vol 7 ◽  
Author(s):  
Ramgopal Mopuri ◽  
Mugagga Kalyesubula ◽  
Alexander Rosov ◽  
Nir Edery ◽  
Uzi Moallem ◽  
...  
Keyword(s):  
Fat Content ◽  
Liver Fat ◽  
Fat Quantification ◽  
Accuracy And Precision ◽  
Folch Method ◽  
Pregnancy Toxemia ◽  
Tissue Lipids ◽  
Hepatic Fat ◽  
Reported Data ◽  
Liver Fat Quantification

Fatty liver represents a significant metabolic pathology of excess intrahepatic fat in domestic animals and humans. Quantification of hepatic-fat content is therefore essential for diagnosis and investigation of liver and metabolic disease. However, the reproducibility of hepatic steatosis analysis is often low due to subjective and technical factors. We hypothesized that improvement in tissue-lipids extraction efficiency would contribute to the accuracy and precision of liver-fat determination. To test it, we investigated the effect of standardized tissue sonication on liver-fat quantification by the Folch method in sheep. Liver samples from grownup lambs of lean (n = 16) and fatty (n = 15) livers, and from pregnant ewes (n = 6) who died from pregnancy toxemia (PT), were used for hepatic-fat content determination with or without tissue sonication. In the grown lambs, an average hepatic-fat content of 6.6% was determined in sonicated compared to 5.1% in non-sonicated specimens (P = 0.0002). Similarly, in ewes with PT, an average of 12.5% was determined with sonication compared to 10.8% without it (P = 0.0006), and the reproducibility was higher with sonication (CV of 3.1 vs. 6.1%, respectively). Thus, tissue sonication improved the efficiency of liver-lipids extraction and was significant to the accuracy and precision of hepatic-fat determination. Enzymatic quantification of triglycerides was moderately correlated with the results obtained gravimetrically (r = 0.632, P < 0.005). The reported data provide reliable reference values for pregnancy toxemic sheep. The significant improvement in liver-fat quantification observed with the reported revised protocol is likely applicable to most mammals and humans.

scholarly journals Free-breathing liver fat quantification using a multiecho 3D stack-of-radial technique

2017 ◽  
Vol 79 (1) ◽  
pp. 370-382 ◽  
Author(s):  
Tess Armstrong ◽  
Isabel Dregely ◽  
Alto Stemmer ◽  
Fei Han ◽  
Yutaka Natsuaki ◽  
...  
Keyword(s):  
Free Breathing ◽  
Liver Fat ◽  
Fat Quantification ◽  
Liver Fat Quantification

Liver fat quantification using fast kVp-switching dual energy CT

2011 ◽  
Author(s):  
Andras Kriston ◽  
Paulo Mendonça ◽  
Alvin Silva ◽  
Robert G. Paden ◽  
William Pavlicek ◽  
...  
Keyword(s):  
Dual Energy ◽  
Liver Fat ◽  
Dual Energy Ct ◽  
Fat Quantification ◽  
Liver Fat Quantification

scholarly journals MRI liver fat quantification in an oncologic population: the added value of complex chemical shift-encoded MRI

2018 ◽  
Vol 52 ◽  
pp. 193-199 ◽  
Author(s):  
Giuseppe Corrias ◽  
Simone Krebs ◽  
Sarah Eskreis-Winkler ◽  
Davinia Ryan ◽  
Junting Zheng ◽  
...  
Keyword(s):  
Chemical Shift ◽  
Added Value ◽  
Liver Fat ◽  
Fat Quantification ◽  
Complex Chemical ◽  
Liver Fat Quantification

Liver fat quantification: Comparison of dual-echo and triple-echo chemical shift MRI to MR spectroscopy

2015 ◽  
Vol 84 (8) ◽  
pp. 1452-1458 ◽  
Author(s):  
Janakan Satkunasingham ◽  
Cecilia Besa ◽  
Octavia Bane ◽  
Ami Shah ◽  
André de Oliveira ◽  
...  
Keyword(s):  
Chemical Shift ◽  
Mr Spectroscopy ◽  
Liver Fat ◽  
Fat Quantification ◽  
Chemical Shift Mri ◽  
Dual Echo ◽  
Liver Fat Quantification

Liver Fat Quantification by Dual-echo MR Imaging Outperforms Traditional Histopathological Analysis

2012 ◽  
Vol 19 (10) ◽  
pp. 1208-1214 ◽  
Author(s):  
Michael A. Fischer ◽  
Dimitri A. Raptis ◽  
Matteo Montani ◽  
Rolf Graf ◽  
Pierre-Alain Clavien ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Liver Fat ◽  
Histopathological Analysis ◽  
Fat Quantification ◽  
Dual Echo ◽  
Liver Fat Quantification
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